A5030865785- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal disorders and treatments
- COVID-19 and healthcare impacts
- Appendicitis Diagnosis and Management
- Thyroid Cancer Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Diverticular Disease and Complications
- Intestinal and Peritoneal Adhesions
- Abdominal Surgery and Complications
- Gastrointestinal Bleeding Diagnosis and Treatment
- Curcumin's Biomedical Applications
- Esophageal and GI Pathology
- Global Health and Surgery
- Abdominal Trauma and Injuries
- Artificial Intelligence in Healthcare and Education
- Hernia repair and management
- Trauma and Emergency Care Studies
- Diversity and Career in Medicine
- Intestinal Malrotation and Obstruction Disorders
- Abdominal vascular conditions and treatments
- Gastrointestinal Tumor Research and Treatment
- Colorectal and Anal Carcinomas
- Radiomics and Machine Learning in Medical Imaging
- Frailty in Older Adults
- Surgical site infection prevention
Sağlık Bilimleri Üniversitesi
2020-2024
Bağcılar Eğitim ve Araştırma Hastanesi
2016-2024
University of Health Sciences
2022-2023
Istanbul University
2023
University of Health Science
2023
Harvard University
2018-2022
Massachusetts General Hospital
2020-2022
United States University
2022
Beykent University
2021
Bursa Uludağ Üni̇versi̇tesi̇
2011-2018
Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global priority not fully understood. We quantified burden SSI after gastrointestinal surgery in countries all parts world.
Abstract Background Severe complicated intra-abdominal sepsis (SCIAS) has an increasing incidence with mortality rates over 80% in some settings. Mortality typically results from disruption of the gastrointestinal tract, progressive and self-perpetuating bio-mediator generation, systemic inflammation, multiple organ failure. A further therapeutic option may be open abdomen (OA) management negative peritoneal pressure therapy (NPPT) to remove inflammatory ascites attenuate damage SCIAS,...
Objective Gastrointestinal (GI) bleeding commonly requires intensive care unit (ICU) in cases of potentialhaemodynamiccompromise or likely urgent intervention. However, manypatientsadmitted to the ICU stop and do not require further intervention, including blood transfusion. The present work proposes an artificial intelligence (AI) solution for prediction rebleeding patients with GI admitted ICU. Methods A machine learning algorithm was trained tested using two publicly available databases,...
Artificial intelligence (AI) and machine learning are central components of today's medical environment. The fairness AI, i.e. the ability AI to be free from bias, has repeatedly come into question. This study investigates diversity members academia whose scholarship poses questions about AI. articles that combine topics fairness, artificial intelligence, medicine were selected Pubmed, Google Scholar, Embase using keywords. Eligibility data extraction done manually cross-checked by another...
BACKGROUND:We evaluated the feasibility of chitosan-coated sutures for intestinal anastomosis strength through wound-healing effect. METHODS:Vicryl and PDS were coated with 2% chitosan.While laparotomy was applied to first group, chitosan in peritoneal cavity second group.Then following materials colon anastomosis, order: Vicryl, PDS, sutures.On 7 th 14 days, eight rats from each group euthanized. RESULTS:The adhesion scores control groups lower than suture groups.The vascularization...
BACKGROUND: Diverticulitis is separated into complicated and uncomplicated, based on the patient’s presentation at time of his or her initial attack acute diverticulitis. OBJECTIVE: The aim this study was to identify risk factors for persistent complex diverticulitis, defined as an abscess, fistula, stricture, elective surgery, characterize outcomes in patient population. DESIGN: This a retrospective review 2010 2016 American College Surgeons National Surgical Quality Improvement Project...
ABSTRACT OBJECTIVE Artificial intelligence (AI) and machine learning are central components of today’s medical environment. The fairness AI, i.e. the ability AI to be free from bias, has repeatedly come into question. This study investigates diversity members academia whose scholarship poses questions about AI. METHODS articles that combine topics fairness, artificial intelligence, medicine were selected Pubmed, Google Scholar, Embase using keywords. Eligibility data extraction done manually...
Radiation proctitis (RP) is inflammation and damage to the rectum, manifested secondary ionizing radiation utilized for treatment. In this study, we evaluated anti-inflammatory therapeutical protective effects of ruscogenin in a model acute RP.Thirty-two Sprague-Dawley rats were divided into 4 groups (n = 8) as sham, control, treatment, prophylaxis groups. Prophylaxis group treatment dosed by oral gavage 14 days pre- postradiation. At end 28th day, all subjects sacrificed.Histopathological...
BACKGROUND:Curcumin is an antioxidant and anti-inflammatory molecule known to be a potent inhibitor of nuclear factor kappa B (NF-kappa B).In this study, we aimed investigate the therapeutic effects curcumin on colitis induced by 2,4,6-trinitrobenzene sulfonic acid (TNBS). METHODS:After induction under anesthesia, 42 rats were divided into six groups as follows; oral group, (20 mg/kg); corn oil mg/kg) using gastric gavage, rectal curcumin; oil; control 1 mL saline solution (0.9% NaCl)...
Abdominal cocoon syndrome (ACS), also called sclerosing encapsulated peritonitis, is a condition characterized by encapsulation of all or some small bowel loops thick fibrous membrane. Etiologic cause not fully known. It among the rare causes intestinal obstruction in adults. Preoperative diagnosis difficult, and high suspicion required. Diagnosis generally made during laparotomy performed due to mechanical obstruction. In treatment condition, large scale surgical resections should be...
Although the English-language literature is full of studies about post-surgical adhesions, no definitive method has yet been identified to prevent them. The goal this study was investigate effect ClinOleic on reducing adhesion formation.Surgery performed 40 adult female Sprague-Dawley rats that were randomly assigned receive either intraperitoneal ClinOleic, which used mimic chyle (ClinOleic group), soybean oil (soybean olive (olive or 0.9% NaCl suspension (control group). All underwent...
This study aimed to investigate factors associated with the development of ileostomy complications in rectal cancer patients, including those who received neoadjuvant treatment.This retrospective trial included 133 consecutive patients underwent surgery for temporary diverting ileostomy. Patients' demographic characteristics as well pre- and postclosure outcomes were analyzed.In logistic regression analysis, longer duration emerged a significant independent predictor any complication during...
We investigated the postsurgical effects of splenectomy with additional curcumin therapy, as an antioxidant, anti-inflammatory substance among lipid profile and histopathological changes.32 rats were randomly divided into four groups: control group (L): laparotomy, sham group: (S), treated (SC) corn oil (SCO) for 28 days. The primary outcomes; total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), low-density (LDL), oxidized LDL (ox-LDL) very-low-density (VLDL)...
Introduction: In this study, we aimed to detect anxiety levels of the physicians during Coronavirus Disease 2019 (COVID-19) pandemic and assess knowledge, perspective, willingness about telemedicine. Materials Methods: This was a survey study from different specialties who provided patient care in Turkey. A total 824 responded questionnaire, which consisted 5 sections: (1) demographic characteristics; (2) level; (3) knowledge; (4) perspective; (5) use Results: Fifty-six percent participants...
Introduction: Although fine-needle aspiration biopsy (FNAB) with cytologic interpretation using the Bethesda System for Reporting Thyroid Cytopathology has been widely used thyroid nodules, its efficiency in categories of III, IV, and V questioned due to variable risk malignancy. We aimed evaluate impact radiological parameters category Methods: performed a retrospective review patients V, subsequent thyroidectomy. Demographic, ultrasonographic, clinical variables were recorded. Independent...
The minimum harvested 12 lymph nodes (LNs) is regarded as the limit for accurate staging of nodal status in colorectal cancer patients. Besides association lengths resected intestinal segments and vascular pedicles, mesocolic mesenteric area's impact on LN count has not been studied. We aimed to evaluate associations between metric variables, including mesentery area harvest.All consecutive patients who underwent elective colectomy with a curative intention colon adenocarcinoma were...
Older patients undergoing emergency laparotomy have high morbidity and mortality rates. Preoperative risk assessment with good predictors is an appropriate measure in this population. Frailty status significantly associated postoperative outcomes older adults. This study aimed to investigate the effect of preoperative factors frailty on short-term following surgery for acute abdomen patients.This included (≥65 years age) who underwent abdominal surgery. We retrospectively analyzed their...
Aim: The aim of study was to review the results overlapping sphincteroplasty in treatment anal incontinence after obstetric injury.Method: Patients with trauma iterated our unit were included study.Patients demographic data, anal, duration incontinence, number surgical operations recorded.Pre-and postoperative scores (Cleveland Clinic _ Incontinence Score -CC IS) and faecal quality life (FIQLI) evaluated.Results: There 42 patients study.The range patient age between 17 62 years old.Mean...
Aim: Curcumin has anti-inflammatory, antioxidant, hypolipidaemic properties.We investigated curcumin on lipid and oxidative stress parameters following splenectomy in rats.Method: 28 rats were operated under general anaesthesia, then fed for 30 days by gastric lavage.The group (CS), the corn oil (COS), control (L), only laparotomy; sham (S), was performed.After days, colectomy performed histopathology.The blood intestinal tissue paraoxonase 1 (PON 1), oxide low density lipoprotein (oxLDL),...