- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular Issues in Pregnancy
- Blood groups and transfusion
- Adipokines, Inflammation, and Metabolic Diseases
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Transplantation: Methods and Outcomes
- Acute Ischemic Stroke Management
- Organ and Tissue Transplantation Research
- Blood Coagulation and Thrombosis Mechanisms
- Advanced battery technologies research
- Vascular Procedures and Complications
- Synthesis and Biological Evaluation
- Liver Disease Diagnosis and Treatment
- Ferrocene Chemistry and Applications
- Cardiac Arrhythmias and Treatments
- Hepatitis C virus research
Cleveland Clinic
2024
Penn State Milton S. Hershey Medical Center
2018-2024
Pennsylvania State University
2018-2023
Mayo Clinic in Florida
2018
Wake Forest University
2017
Mayo Clinic
2015-2016
Atrium Health Wake Forest Baptist
2016
Mayo Clinic in Arizona
2012-2014
Several markers detected on the routine 12-lead ECG are associated with future heart failure events. We examined whether these able to separate risk of reduced ejection fraction (HFrEF) from preserved (HFpEF).We analyzed data 6664 participants (53% female; mean age 62±10 years) MESA (Multi-Ethnic Study Atherosclerosis) who were free cardiovascular disease at baseline (2000-2002). A competing risks analysis was used compare association several predictors HFrEF and HFpEF during a median...
Heart transplantation (HT) is the only option for most patients with end-stage heart failure and hypertrophic cardiomyopathy (HCM) who fail medical therapy. Data on long-term outcomes post-transplant in HCM individuals remain scarce.
The introduction of the new heart allocation system in United States 2018 resulted an increase number transplants (HT) performed among patients with hypertrophic cardiomyopathy (HCM). However, whether that affected medium-term post-HT outcomes this group remains unknown. We conducted analysis Network for Organ Sharing Transplant Database, including adults HCM who underwent transplantation between 2015 and 2021. Patients were divided into two equal-duration eras: Era 1 (October 17, 2015, to...
Mechanical circulatory support has emerged as a vital therapeutic modality for patients awaiting heart transplantation (HT). However, it is unknown how affected the characteristics and post-HT outcomes of with hypertrophic cardiomyopathy (HCM). This retrospective cohort study analyzed adult HT recipients from International Society Heart Lung Transplantation registry (1998-2017). Two equal-duration eras were defined: era 1 1998-2007 2 2008-2017. Patients HCM compared across two (n1 = 742 n2...
Background: A number of studies have shown usefulness the electrocardiogram (ECG) in predicting heart failure (HF). However, whether these ECG predictors can distinguish between risk with reduced (HFrEF) and preserved (HFpEF) ejection fraction is unknown. Methods: We analyzed data 6,638 participants (53% female; mean age 62±10 years) from Multi-Ethnic Study Atherosclerosis who were free cardiovascular disease at time enrollment. Digital ECGs collected centrally read baseline (2000-2002)...
Topic: 34. Thrombosis and vascular biology - Biology & Translational Research Background: Increasing Von Willebrand factor (VWF) correlates with the development of left atrial blood stasis in non-valvular fibrillation (NVAF). However, long-term impact elevated VWF relative to ADAMTS13 activity level, its key regulator, is not well established patients NVAF. Aims: To assess levels on clinical outcomes NVAF normal sinus rhythm controls. Methods: Baseline antigen, activity, echocardiographic...
BACKGROUND. Nearly half of strokes in non-valvular atrial fibrillation (NVAF) are due to non-cardioembolic mechanisms including carotid disease, lacune, watershed, venous sinus thrombosis, or hemorrhage. Tools capable identifying those AF patients most likely suffer a cardioembolic complication would be very helpful for deciding which treat with anticoagulants compared aspirin. CHA 2 DS -VASc has been advocated as an improved stroke risk assessment tool NVAF patients. METHODS. was CHADS the...