A5069244384- Control Systems and Identification
- Fault Detection and Control Systems
- Target Tracking and Data Fusion in Sensor Networks
- Distributed Sensor Networks and Detection Algorithms
- Distributed Control Multi-Agent Systems
- Neural Networks and Applications
- Adaptive Control of Nonlinear Systems
- Neural Networks Stability and Synchronization
- Structural Health Monitoring Techniques
- Advanced Control Systems Optimization
- Advanced Adaptive Filtering Techniques
- Smart Grid Security and Resilience
- Stability and Control of Uncertain Systems
- Genetic Associations and Epidemiology
- Advanced Algorithms and Applications
- Image and Signal Denoising Methods
- Probabilistic and Robust Engineering Design
- Statistical Methods and Inference
- Iterative Learning Control Systems
- Credit Risk and Financial Regulations
- Network Security and Intrusion Detection
- Industrial Technology and Control Systems
- Blind Source Separation Techniques
- Inertial Sensor and Navigation
- Protein Structure and Dynamics
Chinese Academy of Sciences
2016-2025
University of Chinese Academy of Sciences
2010-2025
Zhengzhou University
2025
Beihang University
2023-2025
Academy of Mathematics and Systems Science
2016-2025
Shandong First Medical University
2024
State Grid Corporation of China (China)
2024
Lanzhou Jiaotong University
2024
Second Affiliated Hospital of Jilin University
2024
Taiyuan University of Science and Technology
2024
This article addresses the security issue against data tampering attacks in identification of finite impulse response (FIR) systems with binary-valued observations. First, rate and estimation error caused by network attack are derived. From perspective attacker, it is investigated how to achieve maximum effect minimum energy. Second, compensation-type defense scheme designed. Under this, algorithm constructed, its strong convergence proved. Taking covariance matrix as performance index,...
Abstract Motivation: The use of allosteric modulators as preferred therapeutic agents against classic orthosteric ligands has colossal advantages, including higher specificity, fewer side effects and lower toxicity. Therefore, the computational prediction sites in proteins is receiving increased attention field drug discovery. Allosite a newly developed automatic tool for interest now available through web server. Availability: server tutorials are freely at http://mdl.shsmu.edu.cn/AST...
Gene-environment interaction (G×E) analysis elucidates the interplay between genetic and environmental factors. Genome-wide association studies (GWAS) have expanded to encompass complex traits like time-to-event ordinal traits, which provide richer phenotypic information. However, most existing scalable approaches focus only on quantitative or binary traits. Here we propose SPAGxECCT, a accurate framework for diverse trait types. SPAGxECCT fits genotype-independent model employs hybrid...
The phosphatidylinositol 3-kinase (PI3K) signaling pathway plays important roles in cell proliferation, growth, and survival. Hyperactivated PI3K is frequently found a wide variety of human cancers, validating it as promising target for cancer therapy. We determined the crystal structure PI3Kα-PI103 complex to unravel molecular interactions. Based on structure, substitution at R1 position phenol portion PI103 was demonstrated improve binding affinity via forming new H-bond with Lys802 bottom...
This paper studies consensus problems of multi-agent systems with binary-valued communications. Different from most existing works, the agents considered in this can only get observations its neighbors' states random noises. A algorithm is proposed: first, each agent estimates by recursive projection algorithm; then, designs control timely based on estimates. It proved that converge to true a faster convergence rate than parameter estimation. Moreover, achieve mean-square consensus, and...
With the popularization and application of cyber–physical systems in many industry infrastructure fields, security issue has been quite an important concern. This article addresses defense problem against data tampering attack under framework system identification with binary-valued observations. From perspective attacker, it is shown that how to achieve maximum hit effect least energy. defender, a so-called compensation-oriented approach proposed, corresponding algorithm designed. The...
The activation of molecular chaperone heat-shock protein 90 (Hsp90) is dependent on ATP binding and hydrolysis, which occurs in the N-terminal domains protein. Here, we have determined three crystal structures domain human Hsp90 native complex with analog, providing a clear view catalytic mechanism hydrolysis by Hsp90. Additionally, leads to be an intermediate state that could used partially explain why isolated has very weak hydrolytic activity.
This paper studies the consensus of multiagent systems with binary-valued communication. We consider a group agents on an undirected graph fixed topology, differing from most existing work, information each agent gets its neighbors are measurements stochastic noises. A two-time-scale protocol that alternates estimation and control is constructed: Each in system estimates states neighbors' based for dwelt time, during which every agent's state will keep constant; Based estimations own state,...
In this article, for the single-input–single-output (SISO) nonlinear strict-feedback system, optimized backstepping (OB) control combined with dynamic surface (DS) technique is developed. OB to make every subsystem of as one so ensure entire being optimized. However, original design still needs repeatedly calculate derivative virtual controls, a result, it will inevitably cause problem "differential explosion." order alleviate phenomenon, DS technique. Furthermore, conduct reinforcement...
This work is concerned with identification of Hammerstein systems whose outputs are measured by quantized sensors. The system consists a memoryless nonlinearity that polynomial and possibly noninvertible, followed linear subsystem. parameters nonlinear parts unknown but have known orders. Input design, algorithms, their essential properties presented under the assumptions distribution function noise quantization thresholds known. concept strongly scaled full rank signals introduced to...
Abstract Wearable epidermic electronics assembled by conductive hydrogels exhibit great application potential for their seamless integration with the human body human‐machine interactions (HMI). However, most multifunctional hydrogel sensors are prone to water loss and become useless e‐waste, resulting in a growing threat global environment health. Inspired resurrection plants, this paper introduces reversible intermolecular forces physical crosslinking method into system obtain fully...