A5079783277- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Memory and Neural Mechanisms
- Neurotransmitter Receptor Influence on Behavior
- Renin-Angiotensin System Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Parasite Biology and Host Interactions
- Hormonal Regulation and Hypertension
- Regulation of Appetite and Obesity
- Schizophrenia research and treatment
- Nematode management and characterization studies
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Sleep and Wakefulness Research
- Insect and Arachnid Ecology and Behavior
- Helminth infection and control
- Adipose Tissue and Metabolism
- Parasites and Host Interactions
- Plant Growth Enhancement Techniques
- Neuropeptides and Animal Physiology
- Diet and metabolism studies
- Wastewater Treatment and Reuse
- Birth, Development, and Health
- Sperm and Testicular Function
RMIT University
2011-2025
Roosevelt University
2024
John Wiley & Sons (United States)
2022
Queen's University Belfast
2006-2016
The University of Melbourne
1993-2007
Florey Institute of Neuroscience and Mental Health
1998-2007
Cardiff University
1963-2005
University of St Andrews
2001-2004
University of Portsmouth
1993-1999
Heidelberg Repatriation Hospital
1997
Human immunodeficiency virus (HIV) persistence in blood and tissue reservoirs, including the brain, is a major barrier to HIV cure possible cause of comorbid disease. However, size replication competent nature central nervous system (CNS) reservoir unclear. Here, we used intact proviral DNA assay (IPDA) provide first quantitative assessment defective brain people with (PWH).Total, intact, proviruses were measured autopsy frontal lobe from viremic (n = 18) or virologically suppressed 12) PWH....
Abstract: The effect of chronic inhibition the angiotensin‐converting enzyme on dopamine content and release in striatum was investigated using vivo microdialysis awake, freely moving rats. Rats were treated for 1 week with inhibitor perindopril (1 mg/kg) via drinking water, whereas controls given water alone. One after treatment, striatal dialysate levels group markedly elevated compared control values: control, 233 ± 43 pg/ml; perindopril, 635 53 pg/ml ( p < 0.001). These results...
Obesity can lead to cognitive dysfunction including poor performance in memory tasks. However, is not seen all obese humans and takes several months develop animal models, indicating the adult brain relatively resistant obesity's effects. We have that, rat, overfeeding for as little 3 weeks early life leads lasting obesity microglial priming hypothalamus. Here we hypothesized that hyper-sensitivity neonatally overfed rats extends beyond hypothalamus into memory-associated regions, resulting...
Here, we provide the first regional analysis of intact and defective HIV reservoirs within brain. Brain tissue from both viremic virally suppressed people with (PWH) harbored pol DNA in all regions tested, lower levels present basal ganglia cerebellum relative to frontal white matter. Intact proviruses were primarily found matter but also detected other brain PWH, demonstrating as a major reservoir intact, potentially replication competent that persists despite antiretroviral therapy. ANN...
Sexual dysfunction induced by antipsychotic drug treatment is under investigated and reported. This study aimed to determine the influence of genetic polymorphisms in D2 dopamine receptor (DRD2) endothelial nitric oxide synthase (eNOS) genes, possible role blood prolactin concentrations on sexual function schizophrenic patients.Male remitted patients (n = 100), who were living with a partner receiving monotherapy for at least 6 months, assessed erectile using Arizona Experience Scale...
Adult forms of the pig whipworm, T. suis , are able to establish intimate contact with host's tissues by formation a tunnel-like construction which covers section thread-like oesophageal region. The extreme anterior oral end and stouter posterior region not covered lie free in lumen caecum. attachment tunnel is composed host mucosal cells goblet cell secretion its possible mode discussed. Host tissue directly involved appears unharmed presence parasite. therefore serious pathogen under...
Activity of the immediate early gene c-<i>fos</i> was compared in rats with neurotoxic lesions anterior thalamic nuclei and surgical controls. Fos levels were measured after had been placed a novel room allowed to run up down preselected arms radial maze. An additional control group showed that normal rats, this exposure leads increase number structures, including hippocampus. In contrast, found have significantly less Fos-positive cells an array sites, hippocampus (dorsal ventral),...
Abstract Lesions involving the anterior thalamic nuclei stopped immediate early gene (IEG) activity in specific regions of rat retrosplenial cortex, even though there were no apparent cytoarchitectonic changes. Discrete lesions made either by excitotoxin (Experiment 1) or radiofrequency 2) and, following recovery, rats foraged a radial‐arm maze novel room. Measurements 6–12 weeks postsurgery showed that, comparison with surgical controls, produced same, selective patterns Fos changes...