- Mental Health Treatment and Access
- Schizophrenia research and treatment
- Health disparities and outcomes
- Suicide and Self-Harm Studies
- Employment and Welfare Studies
- Research in Social Sciences
- Psychiatric care and mental health services
- Substance Abuse Treatment and Outcomes
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Electroconvulsive Therapy Studies
- Workplace Health and Well-being
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health, psychology, and well-being
- Alcohol Consumption and Health Effects
- Psychosomatic Disorders and Their Treatments
- Adolescent and Pediatric Healthcare
- Circadian rhythm and melatonin
- Homelessness and Social Issues
- Health Systems, Economic Evaluations, Quality of Life
- Maternal Mental Health During Pregnancy and Postpartum
- Mental Health and Psychiatry
- Treatment of Major Depression
- Poisoning and overdose treatments
- Sleep and related disorders
Pirkanmaa Hospital District
2018-2024
Tampere University
2015-2024
Tampere University Hospital
2016-2023
Finnish Institute for Health and Welfare
2009-2020
Fimlab (Finland)
2020
University of Helsinki
2002-2019
Helsinki University Hospital
2008-2015
Oulu University Hospital
2015
Lapland Central Hospital
2014
University of Oulu
1995-2014
Context:Recent general population surveys of psychotic disorders have found low lifetime prevalences.However, this may be owing to methodological problems.Few studies reported the prevalences all specific disorders.Objective: To provide reliable estimates disorders.Design: General survey.Setting and Participants: A nationally representative sample 8028 persons 30 years or older was screened for bipolar I using Composite International Diagnostic Interview, self-reported diagnoses, medical...
Measurement of health-related quality life (HRQoL) with generic preference-based instruments enables comparisons severity across different conditions and treatments. This is necessary for rational public health policy.To measure HRQoL decrement loss quality-adjusted life-years (QALYs) associated pure comorbid forms depressive anxiety disorders alcohol dependence.A general population survey was conducted Finns aged 30 years over. Psychiatric were diagnosed the Composite International...
Accelerated leukocyte telomere shortening has been previously associated to self-perceived stress and psychiatric disorders, including schizophrenia mood disorders. We set out investigate whether length is affected in patients with anxiety disorders which a known risk factor. also studied the effects of childhood recent psychological distress on length. utilized samples from nationally representative population-based Health 2000 Survey that was carried between 2000–2001 Finland assess major...
Article Abstract Background: Despite the clinical importance of substance-induced psychosis (SIP), few studies have examined course this condition after its acute manifestation. Objective: To investigate rate SIP conversion to a schizophrenia spectrum disorder and length follow-up needed catch majority these patients whose diagnoses change. In addition pattern, we wanted look for possible related factors. Method: Using nationwide Finnish Hospital Discharge Register, followed all (N = 18,478)...
To test whether depression is independently associated with elevated levels of C-reactive protein (CRP) in a large nationwide population-based sample.Depression and CRP were assessed 6005 Finns aged >30 years, as part the ongoing Health 2000 Study. Depression was determined by responses to Beck's Inventory (BDI-21) Composite International Diagnostic Interview (CIDI).Higher scores on BDI-21 related higher (beta = 0.12, p < .001) men 0.08, women. In men, but not women, this relationship...
Objective To examine the associations between an onset of serious mental disorders before age 25 with subsequent employment, income and education outcomes. Methods Nationwide cohort study including individuals ( n = 2 055 720) living in Finland 1988–2015, who were alive at end year they turned 25. Mental disorder diagnosis ages 15 was used as exposure. The level education, employment status, annual wage or self‐employment earnings, total 52 (measurement years 1988–2015) Results All...
Aims: Circadian clock genes are involved in the development of drug-induced behaviors and regulate neurotransmission pathways addiction. Our aim was to study whether circadian gene polymorphisms predispose alcohol dependence or abuse other alcohol-related characteristics. Methods: The sample comprised 512 individuals having (according Diagnostic Statistical Manual Mental Disorders, Fourth Edition (DSM-IV)) their 511 age- sex-matched controls. This population-based drawn from a cohort (n =...
Importance Although incidence of suicide in depression varies remarkably temporally, risk factors have been modeled as constant and remain uncharted the short term. How effectively measured at one point time predict different points is unknown. Objective To examine absolute for hospitalized patients with starting from first days after discharge up to 2 years evaluate whether size relative by factor displays temporal patterns over consecutive phases follow-up. Design, Setting, Participants...
Aims : To assess the variation in heavy drinking and alcohol dependence by living arrangements, contribution of social behavioural factors to this variation. Design The Health 2000 survey is a nationally representative cross-sectional conducted Finland 2000–2001 ( N = 4589 age-range 30–54 years, response rate 81%). Measurements Living arrangements; married, cohabiting, with other(s) than partner, alone. Consumption beer, wine spirits past month was converted into grams alcohol/week,...
Disturbances in the circadian pacemaker system are commonly found individuals with depression and sleep-related problems. We hypothesized that some of canonical clock genes would be associated accompanied by signs disturbed sleep, early morning awakening, or daytime fatigue. tested this hypothesis a population-based sample Health 2000 dataset from Finland, including 384 depressed 1270 controls, all detailed information on sleep vigilance, analyzed set regard to 113 single-nucleotide...
Background Epidemiological data on alcohol-induced psychotic disorder and delirium (alcohol-induced syndrome, AIPS) are scarce. Aims To investigate the epidemiology of AIPS, risk factors for developing AIPS among people with alcohol dependence, mortality associated dependence or without in a sample drawn from general population Finland. Method A 8028 persons were interviewed Composite International Diagnostic Interview screened disorders using multiple sources. Best-estimate diagnoses made...
Individuals with severe mental disorders have an impaired ability to work and are likely receive income transfer payments as their main source of income. However, the magnitude this phenomenon remains unclear. Using longitudinal population cohort register data, authors conducted a case-control study examine levels employment personal before after first hospitalization for serious disorder.All individuals (N=50,551) who had been hospitalized schizophrenia, other nonaffective psychosis, or...
To assess the association of parental education, childhood living conditions and adversities with daily smoking in early adulthood to analyse effect respondent's own main economic activity, current family structure on these associations.The study is based a representative two-stage cluster sample (N = 1894, participation rate 79%) young adults aged 18-29, 2000, Finland. The outcome measure smoking.Parental education had strongest effects smoking. If both parents respondent were smokers, then...
This study examined the association between employment status and specific DSM-IV (Diagnostic Statistical Manual for Mental Disorders, IVth edition) depressive, anxiety alcohol use disorders service these disorders.As part of representative population-based "Health 2000 Study" Finns aged 30 years or over, 3440 employed, 429 unemployed, 820 economically inactive persons working age (30-64 years) participated in a comprehensive health examination, including standardized Composite International...
Aims: To examine the associations between alcohol consumption and utility-based health-related quality of life (HRQoL), subjective (QoL), self-rated health (SRH), mental distress. Methods: Representative general population survey in Finland, with 5871 persons aged 30–64 years. HRQoL was measured two utility instruments (15D EQ-5D), QoL SRH were RATING scales, distress a General Health Questionnaire (GHQ-12). Past problems diagnosed structured psychiatric interview known as composite...
Few general population studies of the treatment major depressive disorder (MDD) have included whole spectrum treatments. We estimated rates different treatments and effect individual characteristics plus provider type on received.In Health 2000 Study, a representative sample (n=6,005) from adult Finnish (> or =30 years) were interviewed (CIDI) in 2000-2001 for presence DSM-IV mental disorders during past 12 months. Logistic regression models used to examine factors influencing treatment:...