A5032437514- Immunotherapy and Immune Responses
- Cancer, Lipids, and Metabolism
- Immune Cell Function and Interaction
- Circular RNAs in diseases
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Glycosylation and Glycoproteins Research
- Genetic factors in colorectal cancer
- Digestive system and related health
- Cell death mechanisms and regulation
- Erythropoietin and Anemia Treatment
- Redox biology and oxidative stress
- Ultrasound and Hyperthermia Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ubiquitin and proteasome pathways
- Chemokine receptors and signaling
- Cancer Cells and Metastasis
- Radiomics and Machine Learning in Medical Imaging
- Cancer-related molecular mechanisms research
- CAR-T cell therapy research
- Sarcoidosis and Beryllium Toxicity Research
- Infectious Diseases and Tuberculosis
- Cell Adhesion Molecules Research
- Cancer, Hypoxia, and Metabolism
Hebei Yiling Hospital
2025
Nanjing General Hospital of Nanjing Military Command
2017-2025
Nanjing University
2011-2025
Nanjing Medical University
2023-2024
Southern Medical University
2023-2024
Abstract Background The aim of this study was to investigate the association survivin expression with metastasis colorectal cancer (CRC). Methods RT‐PCR and Western blot assays were performed detect in CRC cells normal intestinal epithelial cell. gene also detected 15 tissues, surrounding adjacent colon tissues. Moreover, 48 tissues or without lymph node analyzed. Multivariate analysis for using logistic regression model. RNA interference used inhibit analyze its effect on invasion cells....
This study investigates the expression and biological role of caudal homologous transcription factor 2 (CDX2) in duodenal carcinoma. Paraffin-embedded samples from 40 carcinoma cases were analyzed using immunohistochemistry on a tissue microarray to assess CDX2 its prognostic significance. overexpression plasmids CDX2-siRNA transfected into colon cancer cells. Transfection efficiency was confirmed by RT-PCR Western blotting. Cell proliferation assessed CCK8 assay, migration via scratch cell...
e16203 Background: Patients (pts) with primary hepatocellular carcinoma and significant malignant ascites are typically in the terminal stage of disease (BCLC D or CNLC IV), a life expectancy less than three months. Current guidelines recommend best supportive care (BSC) due to lack clinical studies addressing this condition. Preclinical research highlights immunosuppressive cells peritoneal cavity. This study builds on previous case trials assess safety efficacy intraperitoneal PD-1...
e16227 Background: The phase III ClarIDHy trial led to FDA approval of ivosidenib as a therapeutic option for locally advanced or metastatic cholangiocarcinoma (CCA) patients with isocitrate dehydrogenase 1 (IDH1) mutations. However, data regarding its efficacy and safety in Chinese population remains limited. Methods: We retrospectively analyzed survival outcomes IDH1-mutated intrahepatic (iCCA) treated clinical practice at our center from January 2019 2025. Ivosidenib was administered...
Abstract Background Lung cancer (LC) is one of the most common cancers and a leading cause cancer‐related deaths worldwide. In many pathological conditions, particularly in tumor microenvironment, cells tissues frequently exist hypoxic state. Here, we evaluated Itchy E3 ubiquitin protein ligase (ITCH) expression LC following hypoxia treatment. Methods cell lines were treated with condition. Cell migration, invasion, inflammation, reactive oxygen species (ROS) production, apoptosis determined...
Sarcoidosis is an idiopathic multisystem disorder with unknown etiology. Due to clinical similarities among sarcoidosis, tuberculosis (TB) infection and malignant diseases (such as lymphoma, lung carcinoma pituitary tumor), the diagnosis of sarcoidosis challenging. The present report describes a case in 48‑year‑old male complaint chest pain 1 month after Coronavirus disease 2019. patient underwent whole‑body <sup>18</sup>F‑fluorodeoxyglucose (<sup>18</sup>F‑FDG) PET‑CT imaging, which...
Abstract Background PSMD14 played a vital roles initiation and progression of hepatocellular carcinoma (HCC). However, its-related genes for the immune prognostic implications HCC patients have rarely been analyzed. Therefore, we aimed to explore gene signatures values in HCC. Method Analyzed expression multiple databases, clinicopathologic characteristics associated with overall survival using Wilcoxon signed-ranktest, logistic Cox regression, Kaplan-Meier method. An signature (including...
Abstract Background: PSMD14 played a vital roles initiation and progression of hepatocellular carcinoma (HCC). However, its-related genes for the immune prognostic implications HCC patients have rarely been analyzed. Therefore, we aimed to explore gene signatures values in HCC. Methods: Analyzed expression multiple databases, clinicopathologic characteristics associated with overall survival using Wilcoxon signed-ranktest, logistic Cox regression, Kaplan-Meier method. An signature (including...