A5016282045- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Cancer, Hypoxia, and Metabolism
- Gut microbiota and health
- Drug-Induced Hepatotoxicity and Protection
- interferon and immune responses
- Ferroptosis and cancer prognosis
- Drug Transport and Resistance Mechanisms
- Immune cells in cancer
- Diet, Metabolism, and Disease
- Angiogenesis and VEGF in Cancer
- MicroRNA in disease regulation
- Cancer, Stress, Anesthesia, and Immune Response
- Ionosphere and magnetosphere dynamics
- HER2/EGFR in Cancer Research
- Respiratory Support and Mechanisms
- Geophysics and Gravity Measurements
- Hippo pathway signaling and YAP/TAZ
- Inflammasome and immune disorders
- Computational Drug Discovery Methods
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ubiquitin and proteasome pathways
- GNSS positioning and interference
Southern Medical University
2018-2024
Nanfang Hospital
2020-2024
National Time Service Center
2023
Chinese Academy of Sciences
2023
Fundación Juan March
2020
Creative Commons
2020
Tumors display a high rate of glucose metabolism and the SLC2A (also known as GLUT) gene family may be central regulators cellular uptake. However, roles in mechanism metabolite communication with immunity gastric cancer remains unknown.Bioinformatics analysis IHC staining were used to reveal expression SLC2A3 correlation survival prognosis. Real-time PCR, western blots, OCR, ECAR, lactate production uptake assays applied determine effect on glycolysis reprogramming. We then investigated...
Sepsis is a serious condition with high mortality rate worldwide. Granisetron an anti-nausea drug for patients undergoing chemotherapy. Here we aimed to identify the novel effect of granisetron on sepsis-induced acute lung injury (ALI). Our results showed that mice treated displayed less severe damage than controls. administration reduced pulmonary neutrophil recruitment after CLP. Moreover, expressions Cxcl1 and Cxcl2 were diminished in presence THP-1 macrophages lipopolysaccharide...
l-Fucose (Fuc), a six-deoxy hexose monosaccharide, is present endogenously in humans and animals has wide range of biological functions. In the study, we aimed to examine effect Fuc on obesity hepatic steatosis mice fed high-fat diet (HFD). C57BL/6 were normal chow (NC) or HFD for 18 weeks induce fatty liver. was administered intragastrically from 8th week end experiment (18 weeks). Metagenomic analysis showed that altered genomic profile gut microbiota mice; specifically, expression...
The Earth Rotation Parameters (ERPs) are estimated with the BeiDou Navigation Satellite System (BDS), GPS, and Galileo observations from approximately 100 selected International Global (GNSS) Service (IGS) tracking stations around world. results compared IGS final products (IGSF) Reference Systems (IERS) series 14C04 at 12 UTC. accuracy of ERPs derived GPS-only reaches level. standard deviations differences in X-pole, Y-pole, Length Day (LOD), IGSF, 23 μas, 20 7 μs/day, respectively....
Abstract Background We previously found that the intestinal epithelial chemokine (C-C motif) ligand 7 (CCL7) plays an important role in development of toxin-induced acute liver damage. The detailed effects CCL7 on chronic diseases; however, are still unclear. Here, we aimed to investigate impact overexpression high-fat diet (HFD)-induced obesity and steatohepatitis mice. Methods Intestinal (CCL7 tgIEC ) mice their wild-type (WT) littermates were fed with normal chow or HFD for 16 weeks...
Abstract Background: Tumors display a high rate of glucose metabolism and the SLC2A (also known as GLUT) gene family may be central regulators cellular uptake. However, roles in mechanism metabolite communication with immunity gastric cancer remains unknown. Methods: Bioinformatics analysis IHC staining were used to reveal expression SLC2A3 correlation survival prognosis. Real-time PCR, western blots, OCR, ECAR, lactate production uptake assays applied determine effect on glycolysis...
Abstract Background: Tumors display a high rate of glucose metabolism and the SLC2A (also known as GLUT) gene family may be central regulators cellular uptake. However, roles in mechanism metabolite communication with immunity gastric cancer remains unknown. Methods: Bioinformatics analysis IHC staining were used to reveal expression SLC2A3 correlation survival prognosis. Real-time PCR, western blots, OCR, ECAR, lactate production uptake assays applied determine effect on glycolysis...
<title>Abstract</title> 6-phosphofructo-2-kinase (PFKFB3) is an isoenzyme of the PFKFB family, which numerous studies have revealed involvement in tumorigenesis and malignant behaviors a non-glycolysis-dependent manner. Based on our findings PFKFB3 trastuzumab resistance, interestingly, we found that significantly attenuated cisplatin cytotoxicity both vivo vitro. We demonstrated overexpression markedly inhibited Erastin- cisplatin-induced ferroptotic cell death. further showed...