Kai Xu

ORCID: 0000-0003-0154-5830
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Hepatocellular Carcinoma Treatment and Prognosis
  • RNA modifications and cancer
  • Lung Cancer Research Studies
  • Cancer Immunotherapy and Biomarkers
  • Medical Research and Treatments
  • MicroRNA in disease regulation
  • Traditional Chinese Medicine Studies
  • Radiomics and Machine Learning in Medical Imaging
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Economic and Financial Impacts of Cancer
  • Brain Metastases and Treatment
  • Erythropoietin and Anemia Treatment
  • Respiratory viral infections research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Curcumin's Biomedical Applications
  • Actinomycetales infections and treatment
  • Immunotherapy and Immune Responses
  • Healthcare and Venom Research
  • Pleural and Pulmonary Diseases
  • Nutritional Studies and Diet
  • Heart Failure Treatment and Management
  • Immune Cell Function and Interaction

Sichuan University
2021-2025

West China Hospital of Sichuan University
2024-2025

Wenzhou City People's Hospital
2025

Nanjing Medical University
2023-2024

Nantong University
2024

Taizhou People's Hospital
2024

Nanchang University
2023

Third Affiliated Hospital of Nanchang University
2023

First Affiliated Hospital of Jiangxi Medical College
2023

Hangzhou First People's Hospital
2023

Abstract Aims The combination of haemoglobin, albumin, lymphocytes, and platelets (HALP) is a new metric used to assess patient prognosis in many diseases. This study aimed the relationship between HALP short‐ long‐term mortality patients with heart failure. Methods results retrospective cohort included adult failure who were hospitalized 2019 2021. primary outcomes 1‐month 1‐year mortality. multivariable logistic regression analysis was evaluate association risk Stratified analyses...

10.1002/ehf2.14662 article EN cc-by-nc-nd ESC Heart Failure 2024-01-19

This study aims to evaluate the utility of targeted next-generation sequencing (tNGS) in bronchoalveolar lavage fluid (BALF) for hospitalized patients with pulmonary infections. A cohort 358 who received diagnosis and treatment respiratory infections department Respiratory Medicine at Wenzhou People's hospital from January 2023 April 2024 were selected this study. The BALF was analyzed using tNGS, diagnostic efficacy tNGS subsequently compared that conventional testing methods (CTs) pathogen...

10.2147/idr.s499265 article EN cc-by-nc Infection and Drug Resistance 2025-01-01

To compare the survival difference among lobectomy, segmentectomy, and wedge resection investigate role of adjuvant chemotherapy for early-stage small-sized non-small cell lung cancer (NSCLC) with visceral pleural invasion (VPI).Patients diagnosed stage IB peripheral NSCLC VPI ≤3 cm in size Surveillance, Epidemiology, End Results database between 2004 2015 were included, layer (PL) status was identified to recognize tumors VPI, including PL1 PL2. We conducted Cox proportional hazards model...

10.3389/fonc.2022.830470 article EN cc-by Frontiers in Oncology 2022-02-18

10.1016/j.urolonc.2024.12.101 article EN Urologic Oncology Seminars and Original Investigations 2025-02-27

Immune checkpoint inhibitors (ICIs) were promising medical treatments for advanced or metastatic non-small cell lung cancer (NSCLC), while the financial toxicity could not be neglected due to high cost which might impair prognosis and quality of life. Thus, we compared cost-effectiveness analyses identify potential NSCLC received ICIs. A systematic literature search was performed published economic evaluation ICIs in Medline Web Science databases between January 2015 September 2021. Only...

10.2147/rmhp.s504442 article EN cc-by-nc Risk Management and Healthcare Policy 2025-03-01

Diabetic nephropathy (DN) is a metabolic disease wherein chronic hyperglycemia triggers various renal cell dysfunctions, eventually leading to progressive kidney failure. Rosa laevigata Michx. traditional Chinese herbal medicine. Many studies have confirmed its antioxidative, anti-inflammatory, and renoprotective effects. However, the effects mechanisms of polysaccharide (RLP) in DN remain unclear. In this study, mouse model was established investigate therapeutic effect RLP on mice. Then,...

10.1155/2023/9164883 article EN cc-by Journal of Diabetes Research 2023-10-05

To examine whether a combinative treatment with curcumin enhances the effects of epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) gefitinib on cell proliferation, clonogenic capacity and apoptosis in drug-resistant lung cancer line NCI-H1975, further investigate molecular mechanisms involved.NCI-H1975 cells were treated alone or combination, examined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, clone forming experiments, flow cytometry,...

10.1016/s0254-6272(17)30071-7 article EN cc-by-nc-nd Deleted Journal 2017-06-01

Lung cancer was the most common malignancy and leading cause of cancer-related death in China or worldwide, surgery is still preferred treatment for early-stage non-small cell lung (NSCLC). The pattern lymph node metastasis found potentially lobe specific, thus, lobe-specific dissection (L-SLND) proposed to be an alternative systematic (SLND) NSCLC. LobE-Specific diSsectiON trial a single-institutional, randomised, double-blind parallel controlled investigate feasibility L-SLND clinically...

10.1136/bmjopen-2021-056043 article EN cc-by-nc BMJ Open 2022-08-01

With the increasing incidence of stage IA lung cancer ≤1 cm in size, optimal primary treatment remains to be controversial, and thus, we compared survival these patients treated with radiotherapy, wedge resection, segmentectomy, or lobectomy a large population.We identified size between 2004 2015 Surveillance, Epidemiology, End Results (SEER) database. We overall (OS) via Kaplan-Meier analysis conducted Cox regression propensity score matching (PSM) method identify relative hazard ratio (HR)...

10.1016/j.asjsur.2022.04.078 article EN cc-by-nc-nd Asian Journal of Surgery 2022-05-05

This study evaluated the cost-effectiveness of serplulimab plus chemotherapy versus alone in treating advanced/metastatic esophageal squamous cell carcinoma (ESCC) within Chinese health care system.A partitioned survival model based on ASTRUM-007 trial patient characteristics was developed. Efficacy, safety, and medical/economic data were obtained from real-world clinical practice. Costs, quality-adjusted life years (QALY), incremental ratios (ICERs) calculated for both treatment strategies....

10.1177/17588359231213621 article EN cc-by-nc Therapeutic Advances in Medical Oncology 2023-01-01

Pulmonary metastasectomy has been clarified in improving long-term survival most primary malignancies with pulmonary metastasis, while the role of additional lymph node dissection remained controversial. We aimed to investigate prognosis involvement and identify during a real-world cohort. identified patients diagnosed metastases ≤3 cm size received between 2004 2017 Surveillance, Epidemiology, End Results database. compared via Kaplan–Meier analysis propensity score matching method,...

10.1016/j.asjsur.2024.03.051 article EN cc-by-nc-nd Asian Journal of Surgery 2024-04-11

Abstract Background: Molecular subtyping is an essential complementarity after pathological analyses for targeted therapy. This study aimed to investigate the consistency of next-generation sequencing (NGS) results between circulating tumor DNA (ctDNA)-based and tissue-based in non-small cell lung cancer (NSCLC) identify patient characteristics that favor ctDNA testing. Methods: Patients who diagnosed with NSCLC received both ctDNA- NGS before surgery or systemic treatment Lung Cancer...

10.1097/cm9.0000000000003117 article EN cc-by-nc-nd Chinese Medical Journal 2024-05-06

Objective To research the therapeutic effect and toxicity of capecitabine in elderly malignant tumor patients.Methods The data 28 patients were retrospectively analyzed,and RECIST standard was used to evaluate as CR、PR、SD PD.In same time,the observed.Results who have been treated by completed 2cycles therapy.The effective percentage ofthese Was 60.7%(CR 0 pemon,PR 11 persons,SD 6 persons,PD persons).The side controlled.Incidence vomit 39.3%(11 persons),marrow inhibition 25%(7...

10.3760/cma.j.issn.1008-6706.2011.11.025 article EN Zhongguo jiceng yiyao 2011-06-01

AMA Xu K, Feng X, Wang L, Du Q, Jin E. Long-term survival of stage Ib lung adenocarcinoma with postoperative brain oligometastasis: a case report and literature review. Folia Neuropathologica. 2023. doi:10.5114/fn.2023.131120. APA Xu, K., Feng, X., Wang, L., Du, Q., & Jin, (2023). https://doi.org/10.5114/fn.2023.131120 Chicago Kai, Xing Limin Quan Er Jin. "Long-term review". Harvard MLA Kai et al. review." Neuropathologica, Vancouver

10.5114/fn.2023.131120 article EN cc-by-nc-sa Folia Neuropathologica 2023-09-08

Immune checkpoint inhibitor-associated interstitial lung disease (ICI-ILD) and opportunistic pneumonias are the main pulmonary complications during immunotherapy for malignancies. The organizing pneumonia (OP) pattern is one of common radiological manifestations ICI-ILD, OP most cause reversed halo cycles consolidations. However, should be excluded.In this report, we described a case 44-year-old man with esophageal cancer who showed multiple reversed-halo consolidations on chest computed...

10.12998/wjcc.v11.i28.6938 article EN World Journal of Clinical Cases 2023-09-22

<sec> <title>BACKGROUND</title> Previous studies have shown an association between inflammatory diseases and bone metabolism. </sec> <title>OBJECTIVE</title> This study explores the relationship chronic rhinosinusitis (CRS) incident osteoporosis. <title>METHODS</title> We used multivariate Cox regression analysis to explore CRS risk of osteoporosis at individual level in a prospective cohort from UK Biobank. also calculated poly-genetic score (PRS) using genome sequencing data Biobank...

10.2196/preprints.54237 preprint EN 2023-11-04
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