A5016806353- Acute Kidney Injury Research
- SARS-CoV-2 and COVID-19 Research
- Renal Transplantation Outcomes and Treatments
- Antifungal resistance and susceptibility
- Central Venous Catheters and Hemodialysis
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- COVID-19 Clinical Research Studies
- Renal function and acid-base balance
- Neurological Complications and Syndromes
- Dialysis and Renal Disease Management
- Neurological and metabolic disorders
- Fungal Infections and Studies
- Sodium Intake and Health
- Muscle and Compartmental Disorders
- Electrolyte and hormonal disorders
- Pharmacological Effects and Toxicity Studies
- Nail Diseases and Treatments
- Nosocomial Infections in ICU
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Therapeutic Uses of Natural Elements
- Infective Endocarditis Diagnosis and Management
- COVID-19 Impact on Reproduction
- RNA Interference and Gene Delivery
Hospital Clínic de Barcelona
2021-2024
Universitat de Barcelona
2021-2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2021-2024
Recently, several pharmaceutical companies have developed new medium cut-off (MCO) dialyzers for expanded hemodialysis (HDx). This study aimed to compare the safety and efficacy of four MCO dialyzers, against each other versus high-flux (HD) post-dilution hemodiafiltration (HDF).A prospective was carried out on 23 patients who underwent six dialysis sessions: two sessions with FX80 Cordiax in HD HDF, HDx Phylther 17-SD, Vie-18X, Elisio HX19 Theranova 400 dialyzers. The reduction ratios (RRs)...
The medium cut-off Elisio HX dialyzer by Nipro became commercially available in Europe 2021, but there are still no reports of vivo data. This study aimed to evaluate the safety and efficacy it compared with previously evaluated hemodialysis (HD), expanded HD (HDx), postdilution hemodiafiltration (HDF) treatments.A prospective was carried out on 18 patients who underwent 5 dialysis sessions: FX80 Cordiax HD, H19 HX19 HDx, Theranova 400 HDF. reduction ratios urea, creatinine,...
Background. In kidney transplant recipients, there is discordance between the development of cellular and humoral response after vaccination against SARS-CoV-2. We sought to determine interplay 2 arms adaptive immunity in a 3-dose course mRNA-1273 100 μg vaccine. Methods. Humoral (IgG/IgM) (N- S-ELISpot) responses were studied 117 12 kidney-pancreas recipients at following time points: before first dose, 14 d second dose‚ third with median 203 232 start cycle, respectively. Results. After...
Background The age of patients referred for kidney transplantation has increased progressively. However, the precise influence on transplant outcomes is controversial. Methods Etrospective study in which graft and recipient survival were assessed a cohort ≥75 years old recipients compared with contemporary younger one aged 60-65 through propensity score analysis. Results We included 106 between 57 median follow-up 31 [13-54] months. Unadjusted one- five-year did not significantly differ...
Changes in plasma sodium concentration (pNa, expressed mEq/L) are common hemodialysis (HD) patients. Hemodialysis monitors can estimate pNa by using an internal algorithm based on ion dialysance measurements. The present study studies the accuracy of correlation between estimated dialysis monitor and that measured biochemistry laboratory at our center. A single-centre prospective observational patients a chronic HD program with 6008 CAREsystem standard (138 mmol/L) bicarbonate (32...
Introduction: Dialysis catheter-associated bacteremia in Intensive Care Units (ICUs) increases morbidity and mortality, prolongs hospital admission costs. Taurolidine-Citrate-Heparin Locking Solution (TCHLS) is a catheter-locking solution with broad antimicrobial activity against gram-positive gram-negative bacteria fungi. The aim of this study was to analyze the effect systematic sealing hemodialysis catheters ICUs Hospital Clínic de Barcelona on incidence catheter-related blood stream...
Here, we report a case of patient with cloudy effluent that was initially diagnosed as bacterial peritonitis. The persistence despite antibiotic therapy led to an extensive peritoneal dialysis (PD) analysis, the final diagnosis being high-grade B-cell lymphoma. This will increase awareness this rare presentation lymphoproliferative disorder reminding clinicians consider part differential PD effluent.
La encefalopatía por contraste es una complicación neurológica relacionada con el utilizado en procedimientos endovasculares o tomografía computarizada (TC). Los principales factores de riesgo son la hipertensión arterial, diabetes mellitus, enfermedad renal crónica (ERC), contrastes hiperosmolares, cantidad infundida y su infusión directa territorio cerebral posterior, patologías que cursen daño barrera hematoencefálica. sintomatología inespecífica puede presentarse como alteración del...
Introducción: Las alteraciones de la concentración plasmática sodio (Nap, expresado en mEq/L) son frecuentes pacientes hemodiálisis (HD). Los monitores tienen capacidad estimar Nap mediante un algoritmo interno a partir las medidas dialisancia iónica. En el presente estudio se estuda correlacionación entre estimada por monitor diálisis y medida enel laboratorio bioquímica nuestro centro. Material métodos: Estudio observacional prospectivo unicéntrico programa crónico HD con 6008 CAREsystem...
Abstract BACKGROUND AND AIMS Seroconversion after a two-dose course of mRNA COVID-19 vaccination in kidney transplant recipients ranges between 30% and 50% different series. We previously demonstrated that substantial proportion patients (35%) without humoral response, develop cellular response the second dose assessed by ELISpot technique. aim to study evolution both responses same cohort before 1 month administration third 100 mcg mRNA-1273 vaccine. METHOD Final population included 129...
Abstract BACKGROUND AND AIMS The evidence regarding the benefits of performing preemptive SPK (pSPK) is controversial. aim present study was to evaluate impact pSPK on long-term patient and grafts outcomes when compared with npSPK pKTA through a national registry recipients reported Organ Procurement Transplantation Network/United Network for Sharing (OPTN/UNOS) registry, analyse potential associated not only in patients T1D but also T2D. METHOD To explore survival advantage pSPK, we...
Abstract BACKGROUND AND AIMS Dialysis catheter-associated bacteraemia in Intensive Care Units (ICUs) increases morbidity and mortality, prolongs hospital admission costs. TauroLock™ is a lock solution containing (cyclo)-taurolidine (1.35%) citrate (4%). (Cyclo)-taurolidine has broad antimicrobial activity against gram-positive gram-negative bacteria fungi. The objective of this study was to analyse the effect systematic sealing haemodialysis catheters ICUs Hospital Clínic de Barcelona on...
Cardiovascular diseases are the leading cause of mortality and morbidity worldwide. Moreover, chronic kidney disease (CKD) patients exhibit significantly higher incidence prevalence cardiovascular events. In this population, used to a high burden pills, importance polypill-based treatment strategy increases simplify ensure adherence.The polypill composition includes lipid-lowering drug, antihypertensive agent, antiplatelet therapy is marketed in Spain since 2015 with name Trinomia.This...
Abstract Background and Aims a growing number of octogenarians or older patients are being admitted to the intensive care unit (ICU). The aim this study was assess factors associated with acute renal replacement therapy (ARRT) requirement in these impact ARRT on 90-day ICU mortality. Also we aimed identify prognostic mortality risk group that required ARRT. Method retrospective octogenarian ICUs Hospital Clínic de Barcelona from June 2007 April 2019. Patients chronic dialysis treatment...
Abstract Background and Aims Early graft failure (EGL) is a devastating complication of kidney transplantation. Patients with EGL have an increased risk mortality up to twelve times compared patients who received grafts that survive beyond 30 days. Moreover, they may become sensitized antigens from the failed human leukocyte antigen antibodies (anti-HLA), identified on single bead assays, not be reliable until several weeks after Thus, if rapid re-transplantation occurs, there no certainty...