A5101920529- Inflammatory Bowel Disease
- Pancreatitis Pathology and Treatment
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Pancreatic and Hepatic Oncology Research
- Radiopharmaceutical Chemistry and Applications
- Liver Disease Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Reproductive System and Pregnancy
- Intramuscular injections and effects
- Eosinophilic Esophagitis
- Cardiac electrophysiology and arrhythmias
- Abdominal vascular conditions and treatments
- Appendicitis Diagnosis and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Microscopic Colitis
- Pregnancy and Medication Impact
- Pediatric Hepatobiliary Diseases and Treatments
- Heart Failure Treatment and Management
- Eicosanoids and Hypertension Pharmacology
- Abdominal Surgery and Complications
- Sepsis Diagnosis and Treatment
- Heart rate and cardiovascular health
- Celiac Disease Research and Management
Ankara Bilkent City Hospital
2024
Bilkent University
2024
Memorial Ankara Hospital
2021-2022
Ministry of Health
2022
City Hospital
2021-2022
Altınbaş University
2018
Yüksek İhtisas Üniversitesi
2017
Turkish Society of Hematology
2015
Türkiye Yüksek İhtisas Hastanesi
2014
Trakya University
2001-2009
We aimed to investigate the prognostic importance of platelet-lymphocyte ratio (PLR) and neutro - phil-lymphocyte ratio(NLR) combination for patients diagnosed with acute pancreatitis its relationship mortality.This retrospective study was included 142 pancreatitis. Ranson, Atlanta BISAP 0h, 24h 48h scores were calculated by examining their patient files. The divided into three groups as low-risk, medium-risk high-risk according PLR NLR levels.The number complications such necrotizing...
The aim of our study was to assess the effect methylene blue infusion on plasma levels cytokines in severe sepsis. In a prospective, randomized, double-blind, placebo-controlled study, patients received either 0.5 mg.kg-1.h-1 (MB group, n = 15) or similar volume isotonic saline (control i.v. for 6 hours. Plasma concentrations tumour necrosis factor-alpha, interleukin-1, interleukin-2 receptor, interleukin-6, interleukin-8 were measured by sensitive immunoassays at basal (15 min before start...
We aimed to identify ischemia-modified albumin (IMA) levels in inflammatory bowel disease (IBD) and IBD subgroups, examine its relation with activity index.Sixty-eight patients (35 ulcerative colitis [UC] 33 crohn [CD]) 65 healthy volunteers were included the study. Rachmilewitz scoring system (endoscopic index [EAI]) was used determine UC activity, as for CD (CDAI) used. IMA measurement performed ELISA kit.Ischemia-modified IBD, UC, groups comparably higher than control group (37.7 ng/mL vs...
The aim of this study was to investigate the role platelet-to-lymphocyte ratio (PLR)-neutrophil-to-lymphocyte (NLR) combination, in prediction presence Helicobacter pylori (HP) and its associated complications gastrointestinal system.In all, 1289 patients who underwent esophagogastroduodenoscopy biopsy for HP were included study.The with moderate severe chronic gastritis higher (+) group than (-) group. levels 1-3 atrophy intestinal metaplasia Compared group, had PLR NLR levels. high-risk...
We aimed to identify the levels of soluble tumor necrosis factor-like weak inducer apoptosis (sTWEAK) and interleukin 17A (IL-17A) in inflammatory bowel disease (IBD) examine their relationship with activity.A total 92 patients IBD, which 54 were diagnosed ulcerative colitis 38 Crohn's (CD), 104 healthy controls included study. The Rachmilewitz endoscopic activity index was calculated colitis, CD CD.sTWEAK (P < 0.001) IL-17A = 0.006) higher IBD group than control group. Both subgroups,...
Acute pancreatitis is an abrupt inflammatory disease of the exocrine pancreas and it can occur in different severities. It becoming more common mortal gerontal population. The aim our study was to explore similarities differences between young patients with acute pancreatitis, a special emphasis on over 80 years age.Medical records (n = 1150) were analyzed retrospectively. Several scoring systems including Bedside index for severity Ranson's score, Harmless Physiology Chronic Health...
The frequency of antiheparin−platelet factor 4 antibodies by means antigenic and functional assays ( 14 C-serotonin release assay citrated plasma platelet aggregation) was determined in 115 Turkish patients undergoing cardiac surgery. Blood samples were taken immediately before surgery on days 5 10 ± 2. Platelet counts recorded thrombotic events clinical methods. Antibody generation measured enzyme-linked immunosorbent (n = 44) 115) 15.9%, 34.1%, 65.2%, respectively. Positive from 4.4% day 0...
OBJECTIVE: Visnagin (Vis) is a compound found in the flowers and seeds of Ammi visnaga plant with promising antioxidant anti-inflammatory properties. We aimed to investigate dose-dependent gonadoprotective effects visnagin rats while considering oxidative stress, apoptosis, inflammation-related protein expression levels. MATERIALS AND METHODS: Twenty-eight adult were divided into four groups seven animals each; control, ischemia/reperfusion (I/R), I/R+30Vis, I/R+60Vis. Animals control...
Halothane and its metabolites cause liver damage by decreasing blood flow generating free-radical species. Catechin suppresses lipid peroxidation increases enzyme activity, therefore it seems to be capable of protecting parenchyma against the direct toxic effect halothane. The aim this study was investigate role hepatobiliary scintigraphy in detecting after halothane anaesthesia protective catechin comparison with histo-chemical analysis. Thirty rabbits, divided into three groups (A,...
Liver ischaemia may lead to parenchymal damage depending on the duration of ischaemia. Dimethylsulphoxide (DMSO), a well-known radical oxygen scavenger, is protective agent against ischaemia/reperfusion injury. In this study we aimed investigate role hepatobiliary scintigraphy (HBSc) in detecting effect DMSO. Eighteen rabbits, three groups six, were injected with 37 MBq technetium-99m-mebrofenin via ear veins. Dynamic scintigrams taken for 60 min (1 frame/min). group A, HBSc was performed...
To determine whether isovolumic relaxation flow (IRF) and contraction (ICF) resulted from asynchrony asynergy due to VVI DDD pacemakers modulated neurohormones, we measured neurohormone levels in plasma investigated the characteristics of IRF ICF using Doppler echocardiography.We studied 11 patients with dual-chamber (DDD) patients, ventricular inhibiting mode (VVI). All underwent echocardiography left ventricle. Atrial natriuretic peptide (ANP), brain (BNP), renin aldosteron were measured....
Abstract Background In this study, we aimed to evaluate the demographic and epidemiological trends of Ulcerative Colitis (UC) Crohn’s Disease (CD) in non-endemic era for inflammatory bowel disease (IBD) during past three decades. Methods UC CD patients who had follow-up at least 6 months between June 1993 February 2023 were evaluated retrospectively. Electronic medical databases, personal queries IBD registries have all been used collection data on clinical characteristic patients. Results A...
Objectives: Liver transplantation is increasingly being used in the treatment of end-stage liver disease. Ischemia-reperfusion injury one major problems encountered transplantation. In this study, we aimed to compare effects melatonin, pentoxifylline, and dimethyl sulfoxide (DMSO), hepatic ischemia-reperfusion with different methods such as biochemical/ultrastructural changes hepatobiliary scintigraphy. Methods: Thirty rabbits were Laboratory Experimental Animals Trakya University under...