A5081364018- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Pancreatitis Pathology and Treatment
- Hepatitis C virus research
- Organ Transplantation Techniques and Outcomes
- Liver Diseases and Immunity
- Celiac Disease Research and Management
- Inflammatory Bowel Disease
- Helicobacter pylori-related gastroenterology studies
- Pancreatic and Hepatic Oncology Research
- Adrenal and Paraganglionic Tumors
- Gallbladder and Bile Duct Disorders
- Eosinophilic Esophagitis
- Vasculitis and related conditions
- Trace Elements in Health
- Brucella: diagnosis, epidemiology, treatment
- Systemic Sclerosis and Related Diseases
- Microscopic Colitis
- Hormonal Regulation and Hypertension
- Cardiovascular Function and Risk Factors
- Systemic Lupus Erythematosus Research
- Gastroesophageal reflux and treatments
- Autoimmune Bullous Skin Diseases
- IgG4-Related and Inflammatory Diseases
- Medical and Biological Ozone Research
Gaziantep University
2015-2025
Adıyaman University
2019
Dicle University
2011-2014
We investigated associations between baseline use of immunosuppressive drugs and severity Coronavirus Disease 2019 (COVID-19) in autoimmune hepatitis (AIH).Data AIH patients with laboratory confirmed COVID-19 were retrospectively collected from 15 countries. The outcomes who on immunosuppression at the time compared to not medication. clinical courses classified as (i)-no hospitalization, (ii)-hospitalization without oxygen supplementation, (iii)-hospitalization supplementation by nasal...
Background and Aims: A limited number of drugs are used as standard or alternative therapies in autoimmune hepatitis (AIH). No specific recommendations available for patients failing to respond these therapies. We analyzed the efficacy safety infliximab with AIH. Approach Results: performed a retrospective study 42 AIH who received at 21 liver centers 12 countries. Patients were categorized according reason therapy. group 1 (n=20) had failed standard, second-line (mycophenolate mofetil...
Abstract Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease with remissions and flares. Approximately 20% of UC Patients develop acute severe ulcerative (ASUC), serious condition that refractory to standard therapies leads morbidity mortality. Rescue therapy (salvage therapy) steroids, cyclosporine, and/or infliximab recommended by guidelines.1 The colectomy rate in ASUC remains at around 36% even the biological millennium.2 Upadacitinib (UPA) JAK1 selective inhibitor...
Abstract Background Patient-reported outcome measures (PROMs) are used to assess the effectiveness of treatments received by patients in terms clinical response inflammatory bowel disease (IBD). We aimed evaluate perceived from patient’s perspective using PRO2, IBD Control Questionnaire (ICQ) and Visual Analogue Scale (VAS) at end induction therapy treated with upadacitinib. also correlation PROMs biochemical response. Methods included who underwent upadacitinib 01/07/2024 01/10/2024 ten...
Endoscopic retrograde cholangiopancreatography (ERCP) is an essential diagnostic and therapeutic method for pancreato-biliary disorders in adults, but its use pediatric populations remains limited. This study aims to evaluate the indications, technical success, safety of ERCP patients. A retrospective analysis all procedures performed on patients under 18 years age was conducted at 2 tertiary centers Türkiye (Harran University Gaziantep Hospital) during period between January 2013 May 2024....
Background and Objectives: Non-alcoholic fatty liver disease (NAFLD) is a common chronic associated with significant morbidity, including cardiovascular complications. This study investigates the relationship between NAFLD electrocardiographic parameters indicative of ventricular arrhythmia risk. Materials Methods: We conducted cross-sectional enrolling 136 patients healthy controls. Electrocardiographic parameters—Tp-e interval, QT corrected (QTc) intervals, Tp-e/QTc ratio—were measured...
Malignant melanoma is reported to metastasize all organs of the human body. Although it common for gastrointestinal tract, a located primarily in gastric mucosa an uncommon tumor. Gastrointestinal metastases are rarely diagnosed before death with radiological and endoscopic techniques. In this case report clinical course treatment woman stomach, without any other detectable primary lesion, presented discussed. A 55-year-old Turkish our clinic complaints muscle pain bone left side her chest....
Pancreatic steatosis (PS) is a pathology associated with metabolic syndrome (MS), endocrin and exocrine disfunctions of the pancreas, fatty liver. The data on frequency PS are very limited. We aimed to evaluate detected by transabdominal ultrasonography (TAU) in gastroenterology clinics located different geographical regions Turkey factors it.
Acute pancreatitis is an abrupt inflammatory disease of the exocrine pancreas and it can occur in different severities. It becoming more common mortal gerontal population. The aim our study was to explore similarities differences between young patients with acute pancreatitis, a special emphasis on over 80 years age.Medical records (n = 1150) were analyzed retrospectively. Several scoring systems including Bedside index for severity Ranson's score, Harmless Physiology Chronic Health...
Many rheumatic diseases may cause gastrointestinal manifestations. The goal of this study was to analyze the prevalence and predictors involvement in patients with disorders.A retrospective chart review performed for systemic lupus erythematosus, rheumatoid arthritis, sys- temic sclerosis who have consulted due symptoms. relationship between clinical symptoms, gastroscopic/colo- noscopic findings, histopathological results current drugs disease duration evaluated.A total 364 disorders 740...
The aim of this study was to evaluate the most ideal inflammatory markers for treatment response and determine a cutoff value that could predict culture negative neutrocytic ascite (CNNA) patients.This is retrospective cross-sectional case-controlled study. Patients with CNNA were evaluated by taking ascites fluid sampling at beginning on 5th day treatment. Neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte (LMR), neutrophil-to-monocyte calculated.Of 123 cases cirrhotic disease, 59...
The cardiovascular system is one of the most affected systems in liver cirrhosis (LC) process, especially due to tendency arrhythmia. Since data about relationship between LC and novel electrocardiography (ECG) indexes are lacking, we aimed investigate association Tp-e interval, Tp-e/QT, Tp-e/QTc ratio.The study included 100 patients group (56 male, median age 60) control (52 female, 60 age) January 2021 2022. ECG laboratory findings were analyzed.The patient had significantly higher heart...
The aims of the present study were to evaluate real-life efficacy and tolerability glecaprevir (GLE)/pibrentasvir (PIB) in treatment patients with chronic hepatitis C (CHC).Between May 2019 2022, 686 CHC, treated GLE/PIB combination from 21 participating centers Turkiye, enrolled study.All Caucasian, their median age was 56 years. At start treatment, serum Hepatitis virus RNA alanine amino transaminase (ALT) levels 6.74 log10 IU/mL 47 U/L, respectively. Fifty-three percent infected genotype...
Objective: Adrenal incidentaloma are bulks which stated incidentally by imagining methods or in abdominal laparotomy when there is no suspicion of any disease adrenal gland. With increase using ultrasonography and BT, the frequency determining also increases. In this study, we aimed to examine demographical features insulin resistance patients with non functioning (NFAI). Methods: 30 (20 female–10 male) patients, who followed due NFAI at Dicle University Medical Faculty Department...
Background/Aims: Gastroesophageal Reflux Disease (GERD) is a clinical entity affecting the upper gastrointestinal tract.The pathophysiology of GERD has been associated with autonomic nervous system disorders.Autonomic disturbances in patients have shown to lead fatal ventricular arrhythmias (VAs) that result electrical and repolarization anomalies.The maximum terminal electrocardiographic T wave (Tpe) transmural dispersion.In addition, higher Tpe interval (TpeI) Tpe/QT ratio correspond...
Wilson disease (WD) is an autosomal recessive inherited disorder of copper (Cu2+) metabolism, resulting in Cu2+ accumulation and liver central nervous system toxicity. Oxidative stress may have a role the pathogenesis disease, but roles thiol/disulfide homeostasis nitrosative not been examined. The purpose this study was to evaluate whether there modification patients with disease.A total 50 (42 under drug treatment 8 newly diagnosed no treatment) healthy gender- age-matched controls were...
We aimed to determine the awareness of referring hepatitis C virus patients relevant departments and effect pandemic period on this subject.A total 65 743 with anti-hepatitis requests before during COVID-19 were retrospectively screened. Anti-hepatitis virus-positive divided into 5 groups according age distribution. The distribution positivity was compared groups, COVID-19. virus-pos- itive who not requested RNA evaluated individually departments, COVID-19.Anti-hepatitis rate 1.54% COVID-19;...
Abstract Background This study aims to assess the past decade's epidemiology of inflammatory bowel disease (IBD) patients in Türkiye and identify year-to-year variations. Methods A total 3463 diagnosed between 2010 2022 were included. The patients' demographic phenotypic characteristics, smoking habits, family histories assessed. Differences geographic regions age groups analyzed. Results Among patients, 1523 (44%) had Crohn's (CD), 1768 (51.1%) ulcerative colitis (UC), 23 (0.7%)...
Crohn's disease (CD) is a major subtype of chronic relapsing inflammatory gastrointestinal disorders. In this study, we assessed the possible contributions serum oxidative/nitrosative stress and dynamic thiol/disulfide homeostasis to CD pathogenesis. Patients with active (A-CD) at onset (n = 38), patients in remission (R-CD) healthy controls 38) were prospectively included study. Serum parameters as well total thiol native levels analyzed. We observed significant augmentation nitric oxide...