A5021658769- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Microscopic Colitis
- Liver Disease and Transplantation
- Colorectal Cancer Screening and Detection
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis C virus research
- Liver Diseases and Immunity
- Hepatitis B Virus Studies
- Diverticular Disease and Complications
- Nutrition and Health in Aging
- Autoimmune and Inflammatory Disorders
- Gastrointestinal disorders and treatments
- Health Systems, Economic Evaluations, Quality of Life
- Diet, Metabolism, and Disease
- Sleep and related disorders
- Pancreatitis Pathology and Treatment
- COVID-19 diagnosis using AI
- Gastroesophageal reflux and treatments
- Diet and metabolism studies
- Healthcare cost, quality, practices
- Clinical Nutrition and Gastroenterology
- Colorectal Cancer Treatments and Studies
- Spondyloarthritis Studies and Treatments
- Bariatric Surgery and Outcomes
Marmara University
2014-2025
New York University
2023
NYU Langone Health
2020-2021
Brooklyn Hospital Center
2021
European Foundation for the Study of Chronic Liver Failure
2021
CARE USA
2020
University of Pecs
2020
University of Debrecen
2020
Iuliu Hațieganu University of Medicine and Pharmacy
2020
University Gastroenterology
2019
Acute decompensation (AD) of cirrhosis may present without acute-on-chronic liver failure (ACLF) (AD-No ACLF), or with ACLF (AD-ACLF), defined by organ failure(s). Herein, we aimed to analyze and characterize the precipitants leading both these AD phenotypes. The multicenter, prospective, observational PREDICT study (NCT03056612) included 1,273 non-electively hospitalized patients (No = 1,071; 202). Medical history, clinical data laboratory were collected at enrolment during 90-day...
Abstract Background Azathioprine (AZA)-associated acute pancreatitis (AP) and gastrointestinal intolerance (GI-INT) are common causes of AZA discontinuation in IBD patients1,2. This study compares HLA alleles linked to AZA-AP3,4, along with demographic clinical data, between AP GI-INT patients. Methods Data from five centers were used form three groups: Control (n=88), AZA-AP (n=44), (n=44). Patients diagnosed during treatment per the Atlanta criteria (radiology, elevated amylase/lipase,...
Objective: Depression and anxiety are common disorders in inflammatory bowel disease (IBD). Our aim is to prospectively determine the effect of psychiatric treatment on scores for depression, anxiety, quality life (QoL), sexual dysfunction an outpatient population diagnosed with IBD also and/or depression disorder. Patients methods: who scored higher than cutoff point Hospital Anxiety Scale were referred further structured evaluation determination need drug treatment. underwent therapy...
Background/Aims: Advanced fibrosis (F≥3) indicates poor outcomes in nonalcoholic fatty liver disease (NAFLD).Here, we examined the diagnostic performance of fibrosis-4 index (FIB-4) and NAFLD score (NFS) for detecting (or excluding) advanced patients with biopsy-proven NAFLD.Methods: The each noninvasive test according to previously identified cutoff points indicating low high risk was determined 463 NAFLD.Patients who scored <1.3 >2.67 on FIB-4 were considered at fibrosis,...
SummaryBackgroundPatients with chronic gastrointestinal (GI) disease such as inflammatory bowel (IBD), irritable syndrome (IBS), celiac disease, gastroesophageal reflux (GERD), pancreatitis, and liver (CLD) often suffer from obesity because of coincidence (IBD, IBS, disease) or related pathophysiology (GERD, pancreatitis CLD). It is unclear if patients need a particular diagnostic treatment that differs the needs lean GI patients. The present guideline addresses this question according to...
Abstract Background This study aimed to determine the prevalence of probable sarcopenia and in patients with inflammatory bowel disease (IBD) by using European Working Group on Sarcopenia Older People (EWGSOP2) diagnostic criteria. Methods was assessed sequential four‐step algorithm. (1) Find: risk simple clinical symptom index (strength, assistance walking, rise from a chair, climb stairs, falls [SARC‐F questionnaire]). (2) Assess: Probable low muscle strength handgrip. (3) Confirm:...
Abstract Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease with remissions and flares. Approximately 20% of UC Patients develop acute severe ulcerative (ASUC), serious condition that refractory to standard therapies leads morbidity mortality. Rescue therapy (salvage therapy) steroids, cyclosporine, and/or infliximab recommended by guidelines.1 The colectomy rate in ASUC remains at around 36% even the biological millennium.2 Upadacitinib (UPA) JAK1 selective inhibitor...
Abstract Background Patient-reported outcome measures (PROMs) are used to assess the effectiveness of treatments received by patients in terms clinical response inflammatory bowel disease (IBD). We aimed evaluate perceived from patient’s perspective using PRO2, IBD Control Questionnaire (ICQ) and Visual Analogue Scale (VAS) at end induction therapy treated with upadacitinib. also correlation PROMs biochemical response. Methods included who underwent upadacitinib 01/07/2024 01/10/2024 ten...
Abstract Background Crohn's disease (CD) is a chronic, remitting with sometimes inadequate response to the treatment and these factors may impact quality of life patients. Our study aims evaluate fistulizing disease, different options activity on in CD. Methods Patients who applied inflammatory bowel outpatient clinic between August 2021 September 2023 were invited respectively. agreed participate included study. The patients was assessed Inflammatory Bowel Disease Questionnaire (IBDQ),...
Abstract Background Strictures can be developed in approximately half of the Crohn’s disease (CD) patients during course disease. Stricturing CD treated by medical, endoscopic and surgical options. In this study, we investigated risk factors related surgery postoperative complications stricturing CD. Methods We included with who were followed up our inflammatory bowel specific outpatient clinic between 1989 2024. Demographic clinical data collected retrospectively from hospital electronic...
Abstract Background The best maintenance therapy after a steroid-responsive acute severe ulcerative colitis (ASUC) episode remains poorly studied and is not addressed in current guidelines. We aimed to compare the impact of different treatment strategies following hospitalization for ASUC. Methods Multicentric, multinational, retrospective cohort study including patients hospitalized with ASUC, between 2010-2021, who responded intravenous steroids (Oxford Criteria). Patients were categorized...
Clinical guidelines are a cornerstone of evidence-based medicine. Little is known about clinicians' knowledge guideline development and how they perceive quality. A survey protocol was designed according to the CHERRIES (improving quality web surveys: Checklist for Reporting Results Internet E-Surveys) checklist. The explored three main aspects: high-quality markers guidelines, development, areas improvement. conducted by contacting UEG affiliated societies email via social media. All valid...
Background/Aims: Nonalcoholic fatty liver disease (NAFLD), which consists of nonalcoholic (NAFL) and steatohepatitis (NASH), is a growing epidemic in Turkey, considering the recent alarming prevalence 48.3%.Patients with NASH and/or fibrosis are more likely to progress advanced disease.In this single-center study, we sought describe clinical histological characteristics sample Turkish patients biopsy-proven NAFLD, who were enrolled over 4-year period.Materials Methods: This retrospective...
Assessment of endoscopic activity in ulcerative colitis (UC) is important for treatment decisions and monitoring disease progress. However, substantial inter- intraobserver variability grading impairs the assessment. Our aim was to develop a computer-aided diagnosis system using deep learning reduce subjectivity improve reliability assessment.The cohort comprises 11 276 images from 564 patients who underwent colonoscopy UC. We propose regression-based approach evaluation UC according Mayo...
To determine the incidence rate and distribution of anemia types over time from an Inflammatory Bowel Disease (IBD) patient cohort spanning 18 years.Between January 1995 November 2013, University Hospital digital databases as well hard copies patients' files were reviewed retrospectively. IBD patients with at least one complete blood count (CBC) report included in this study.We obtained 941 records; 375 (39.9%) diagnosed Crohn's disease (CD), 566 (60.1%) had ulcerative colitis (UC). Anemia...
Hepatitis C virus (HCV) infection is known to impair the quality of life (QoL). Increased levels anxiety and depression have been found in HCV with a prevalence 28% 33%, respectively. Our aim was investigate depression, anxiety, QoL chronic hepatitis (CHC) patients before after treatment direct-acting antiviral agent (DAAA).In this study, enrolled CHC who had undergone DAAA our out-patient clinic. We administered Hospital Anxiety Depression (HAD) questionnaire measure severity symptoms Short...
Acid suppressing drugs (ASD) are generally used in acute pancreatitis (AP); however, large cohorts not available to understand their efficiency and safety. Therefore, our aims were evaluate the association between administration of ASDs, outcome AP, frequency gastrointestinal (GI) bleeding GI infection patients with AP. We initiated an international survey performed retrospective data analysis on AP hospitalized January 2013 December 2018. Data 17,422 adult collected from 59 centers 23...
BK-virus (BKV) is an important etiological agent for late-onset hemorrhagic cystitis (HC) in patients undergoing hematopoietic stem cell transplantation. Late-onset HC causes significant morbidity among these patients. Therapeutic approaches remain predominantly symptomatic. Several treatment options have been used with variable success rates. Cidofovir has the highest specificity against BKV; however, its lack of availability majority countries, high costs and potential nephrotoxic effects...