A5086754252- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Liver Disease and Transplantation
- Diet, Metabolism, and Disease
- Esophageal and GI Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- IgG4-Related and Inflammatory Diseases
- Alcohol Consumption and Health Effects
- Hepatitis B Virus Studies
- Neutropenia and Cancer Infections
- Pancreatic function and diabetes
- Acute Myocardial Infarction Research
- Microscopic Colitis
- Colorectal Cancer Screening and Detection
- Gastroesophageal reflux and treatments
- Nonmelanoma Skin Cancer Studies
- Metastasis and carcinoma case studies
- Clostridium difficile and Clostridium perfringens research
- Liver physiology and pathology
Martin Luther University Halle-Wittenberg
2024
Marmara University
2012-2023
Carol Davila University of Medicine and Pharmacy
2020
Çanakkale Onsekiz Mart Üniversitesi
2014
Cornell University
2014
University Gastroenterology
2006
Azienda Ospedaliera Ospedale Maggiore
2006
The overall objective of these guidelines is to provide evidence‐based recommendations for the diagnosis and management immunoglobulin G4 (IgG4)‐related digestive disease in adults children. IgG4‐related can be diagnosed only with a comprehensive work‐up that includes histology, organ morphology at imaging, serology, search other involvement, response glucocorticoid treatment. Indications treatment are symptomatic patients obstructive jaundice, abdominal pain, posterior pancreatic...
Background and aims Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology manifestations. Our were to characterize type 1 AIP in a large pan-European cohort study effectiveness current treatment regimens. Methods We retrospectively analyzed adults diagnosed since 2005 or not-otherwise-specified 42 European university hospitals. Type was uniformly using specific diagnostic criteria. Patients 2 those who had undergone pancreatic surgery...
Antibiotic-associated diarrhoea may develop during or following Helicobacter pylori eradication. We aimed to evaluate the efficacy and safety of Saccharomyces boulardii in preventing antibiotic-associated patients receiving antibiotics for H. eradication.In a multicentre prospective clinical trial, with peptic ulcer disease non-ulcer dyspepsia were enrolled receive clarithromycin, amoxicillin omeprazole eradication 14 days. These then randomized either S. 500 mg twice daily (treatment group)...
Saccharomyces boulardii is a probiotic used for the prevention of antibiotic-associated diarrhoea. We aimed to investigate whether S. could alter effects clarithromycin (CLA) and methotrexate (MTX) on oro-caecal intestinal transit oxidative damage in rats. Rats were divided into two groups receiving single dose MTX (20 mg/kg) or CLA mg/kg per d) 1 week. Groups treated with either saline (500 twice d throughout experiment. The control group was administered only saline. Following...
Background. Patients with end-stage renal disease have a high risk of premature death, which is due mainly to cardiovascular (CV) events. Elevated cardiac troponin T (cTnT) related increased left ventricular mass index (LVMI) and predicts poor outcome in chronic haemodialysis patients. We investigated the prognostic value cTnT its relationship continuous ambulatory peritoneal dialysis (CAPD)
Acid suppressing drugs (ASD) are generally used in acute pancreatitis (AP); however, large cohorts not available to understand their efficiency and safety. Therefore, our aims were evaluate the association between administration of ASDs, outcome AP, frequency gastrointestinal (GI) bleeding GI infection patients with AP. We initiated an international survey performed retrospective data analysis on AP hospitalized January 2013 December 2018. Data 17,422 adult collected from 59 centers 23...
Abstract There are several overlapping clinical practice guidelines in acute pancreatitis (AP), however, none of them contains suggestions on patient discharge. The Hungarian Pancreatic Study Group (HPSG) has recently developed a laboratory data and symptom-based discharge protocol which needs to be validated. (1) A survey was conducted involving all members the International Association Pancreatology (IAP) understand characteristics international protocols. (2) We investigated safety...
BACKGROUND Extraorbital sebaceous carcinoma (SC) is a rare of the skin but known to have good prognosis in terms metastasis and survival. OBJECTIVE To discuss emphasize through clinical histopathologic findings aggressive potential extraorbital SC review corresponding literature. METHODS We present an unusual form that has followed course metastasized rapidly. RESULTS Local excision primary cutaneous tumor with negative margins did not prevent rapid fatal internal organ metastases. The...
In developed countries, there has been a recent increase in the prevalence of adenocarcinoma esophagus and cardia, along with decrease distal gastric cancers. Little is known regarding these diseases developing countries. The aim present study was to evaluate changes adenocarcinomas Turkey as function anatomic location.Data were retrospectively collected from 16 centers January 1990 December 2000. Owing exclusion criteria, total 4065 cases tumors stomach included. Tumors localized body,...
Non-alcoholic steatohepatitis (NASH) is a progressive liver disease characterized by diffuse fatty infiltration and Kupffer cell dysfunction which contributes to its pathogenesis. Since the biopsy, considered 'gold standard' in diagnosing NASH, has some limitations other imaging methods have been explored as alternatives. Colloid scintigraphy good method reflecting activity we found it worthwhile evaluate this technique NASH. We aimed present common scintigraphic features their...
Objectives: Toronto hepatocellular carcinoma risk index is developed to stratify cirrhotic patients according 10-year risk. We aimed validate the performance of in a large Turkish cohort. Materials and methods: retrospectively reviewed database 1287 followed-up period (February 2008 January 2018). All were stratified into three groups based on score as follows: low-risk, < 120; intermediate risk, 120 240; high > 240. Area under curve optimal cutoff value obtained from receiver operator...
Background/Aims: Specific serum markers reflecting hepatic inflammation and fibrosis are required to tailor the treatment strategies in non-alcoholic steatohepatitis (NASH).We aimed investigate roles of myeloperoxidase (MPO) calprotectin predicting status disease severity NASH. Materials Methods: A total 48 patients with biopsy-proven NASH 25 healthy volunteers normal weight were prospectively enrolled. Serum MPO levels compared between control groups. Hepatic expressions terms histologic...
A 78-year-old man with a history of aorta-femoral graft operation was admitted to the hospital symptoms syncope, melena and haematemesis. He reported several episodes during previous year for which he underwent repeated gastro-intestinal endoscopic examinations, were unable show site gastrointestinal bleeding. The third upper examination disclosed yellowish ulcerative lesion irregular borders in part duodenum, considered be fistula, between aorta duodenum. patient an explorative that...