Dóra Illés
A5083882436- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Gastrointestinal disorders and treatments
- Diabetes and associated disorders
- Diabetes Management and Research
- Appendicitis Diagnosis and Management
- Gallbladder and Bile Duct Disorders
- Pancreatic function and diabetes
- Pediatric Hepatobiliary Diseases and Treatments
- IgG4-Related and Inflammatory Diseases
- Healthcare cost, quality, practices
- Diabetes Treatment and Management
- Pneumonia and Respiratory Infections
- Gastroesophageal reflux and treatments
- Dermatological and COVID-19 studies
- Advanced Nanomaterials in Catalysis
- Sepsis Diagnosis and Treatment
- Myofascial pain diagnosis and treatment
- Potassium and Related Disorders
- Climate Change and Health Impacts
- Gastrointestinal Bleeding Diagnosis and Treatment
- Lipid metabolism and disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
University of Szeged
2016-2025
University of Pecs
2020-2023
Semmelweis University
2020-2023
Gomel State Medical University
2020
Helsinki University Hospital
2017-2019
Hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). It has been shown that hypertriglyceridemia aggravates severity and related complications AP; however, detailed analyses large cohorts are contradictory. Our aim was to investigate dose-dependent effect on AP. AP patients over 18 years old who underwent triglyceride measurement within initial three days were included into our cohort analysis from a prospective international, multicenter registry operated by...
The in-hospital survival of patients suffering from acute pancreatitis (AP) is 95% to 98%. However, there growing evidence that discharged after AP may be at risk serious morbidity and mortality. Here, we aimed investigate the risk, causes, predictors most severe consequence post-AP period: mortality.A total 2613 well-characterized 25 centers were included followed by Hungarian Pancreatic Study Group between 2012 2021. A general a hospital-based population was used as control group.After an...
The incidence of acute pancreatitis (AP) and the prevalence metabolic syndrome (MetS) are growing worldwide. Several studies have confirmed that obesity (OB), hyperlipidemia (HL), or diabetes mellitus (DM) can increase severity, mortality, complications in AP. However, there is no comprehensive information on independent joint effect MetS components outcome Our aims were (1) to understand whether an AP (2) examine their combinations.From 2012 2017, 1435 cases from 28 centers included...
Abstract Pancreatic necrosis is a consistent prognostic factor in acute pancreatitis (AP). However, the clinical scores currently use are either too complicated or require data that unavailable on admission lack sufficient predictive value. We therefore aimed to develop tool aid prediction. The XGBoost machine learning algorithm processed from 2387 patients with AP. confidence of model was estimated by bootstrapping method and interpreted via 10th 90th percentiles prediction scores. Shapley...
Background C-reactive protein level (CRP) and white blood cell count (WBC) have been variably used in clinical trials on acute pancreatitis (AP). We assessed their potential role. Methods First, we investigated studies which CRP or WBC, to describe current role AP. Second, extracted the data of 1435 episodes AP from our registry. WBC admission, within 24 hours onset pain highest values were analyzed. Descriptive statistical tools as Kruskal-Wallis, Mann-Whitney U, Levene's F tests, Receiver...
Background: Nonalcoholic fatty pancreas and liver disease (NAFPD NAFLD) pericardial adipose tissue (PAT) are often associated with type 2 diabetes mellitus (T2DM). Our aim was to evaluate the incidence rate of NAFLD NAFPD, PAT size, effect metformin treatment on NAFLD, in new-onset T2DM (NODM). Methods: Seventeen patients NODM 10 subjects used as a control group were involved study. Computed tomography (CT) laboratory tests performed before beginning therapy 4 months afterward. amount fat...
Acid suppressing drugs (ASD) are generally used in acute pancreatitis (AP); however, large cohorts not available to understand their efficiency and safety. Therefore, our aims were evaluate the association between administration of ASDs, outcome AP, frequency gastrointestinal (GI) bleeding GI infection patients with AP. We initiated an international survey performed retrospective data analysis on AP hospitalized January 2013 December 2018. Data 17,422 adult collected from 59 centers 23...
Background/objectives Acute recurrent pancreatitis (ARP) due to alcohol and/or tobacco abuse is a preventable disease which lowers quality of life and can lead chronic pancreatitis. The REAPPEAR study aims investigate whether combined patient education cessation programme for smoking prevents ARP. Methods analysis consists an international multicentre randomised controlled trial (REAPPEAR-T) testing the efficacy on prospective cohort (REAPPEAR-C) assessing effects change in consumption...
Introduction Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis with an overall 5-year survival of approximately 8%. The success in reducing the mortality rate PDAC is related to discovery new therapeutic agents, and significant extent development early detection prevention programmes. Patients new-onset diabetes mellitus (DM) represent high-risk group for as they have eightfold higher risk than general population. proposed screening programme may allow early, operable stage....
Background: Acute pancreatitis (AP) is a life-threatening disease. We aimed to explore the prognostic relevance of renal function based on estimated glomerular filtration rate (eGFR). Methods: A prospective registry AP patients was established by Hungarian Pancreatic Study Group. Data 1,224 consecutive were collected between 2012 and 2017. Patients divided into 3 groups according their eGFR measured within 24 h hospitalization: normal function: >90 mL/min, mild moderate functional...
Disturbance of consciousness (DOC) may develop in acute pancreatitis (AP). In clinical practice, it is known that DOC worsen the patient's condition, but we have no exact data on how affects outcome AP. From Hungarian Pancreatic Study Groups' AP registry, 1220 prospectively collected cases were analyzed, which contained DOC, included patients with confusion, delirium, convulsion, and alcohol withdrawal, answering a post hoc defined research question. Patients separated to Non-DOC whereas was...
Abstract: Introduction: Due to the inappropriate use of antibiotics (AB), more pathogens become multiresistant. One most severe sources sepsis is cholangitis. To avoid fatal outcome, an effective AB policy plays a key role. Aim: investigate resistance bacteria causing cholangitis and efficacy treatment. Patients method: Microbiological tests bile samples collected during cholangitis-indicated endoscopic retrograde cholangiopancreatographies were analysed at First Department Medicine,...
In developed countries, diseases of the gallbladder and biliary tract count as some most frequent gastrointestinal disorders. The inflammation gallbladder/biliary tree is a potentially severe, even lethal condition that requires rapid diagnosis early multidisciplinary approach to be treated. Although frequency these high, treatment not unified in Hungary yet. aim evidence-based recommendation clarify diagnostic criteria severity grading highlight indications rules proper application numerous...
The coronavirus disease 2019 pandemic had a major impact on most medical services. Our aim was to assess the outcome of acute cholecystitis during nationwide lockdown period. All patients admitted our emergency department for AC were analysed. Patient characteristics, performance status, severity, treatment modality and assessed period (Period II: 1 April 2020-30 November 2021) compared historical control I: May 2017-31 December 2018). admissions increased by 72.8% in Period II. Patients...