José Luis Pérez-Hernández

ORCID: 0000-0003-4367-8463
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Alcohol Consumption and Health Effects
  • Hepatitis C virus research
  • Organ Transplantation Techniques and Outcomes
  • Liver Diseases and Immunity
  • Drug-Induced Hepatotoxicity and Protection
  • COVID-19 Clinical Research Studies
  • Pancreatitis Pathology and Treatment
  • Hepatitis B Virus Studies
  • Growth Hormone and Insulin-like Growth Factors
  • Diet, Metabolism, and Disease
  • Appendicitis Diagnosis and Management
  • Dialysis and Renal Disease Management
  • Folate and B Vitamins Research
  • Pancreatic and Hepatic Oncology Research
  • Pediatric Hepatobiliary Diseases and Treatments
  • Diet and metabolism studies
  • Acute Kidney Injury Research
  • Gastroesophageal reflux and treatments
  • Connective Tissue Growth Factor Research
  • Long-Term Effects of COVID-19
  • Systemic Lupus Erythematosus Research
  • SARS-CoV-2 and COVID-19 Research
  • Alcoholism and Thiamine Deficiency

Hospital General de México
2014-2025

Pemex (Mexico)
2010-2024

Patients First
2022

Background & Aim. Despite treatment with glucocorticoids, mortality remains high in patients severe alcoholic hepatitis. Oxidative stress and depletion of mitochondrial glutathione are implicated factors liver injury. The aim this study was to evaluate the impact addition metadoxine, a drug which possesses multifactorial mechanism action, including antioxidant properties, standard glucocorticoids Material methods. This randomized open label clinical trial performed Mexico's General Hospital...

10.1016/s1665-2681(19)30863-4 article EN cc-by-nc-nd Annals of Hepatology 2014-05-01

To investigate the main current etiologies of cirrhosis in Mexico.We performed a cross-sectional retrospective multicenter study that included eight hospitals different areas Mexico. These provide health care to people diverse social classes. The inclusion criteria were histological, clinical, biochemical, endoscopic, or imaging diagnosis liver cirrhosis. Data obtained during 5-year period (January 2012-December 2017).A total 1210 patients included. mean age was 62.5 years (SD = 12.1), and...

10.12998/wjcc.v6.i15.922 article EN World Journal of Clinical Cases 2018-12-06

Alcohol is the most socially accepted addictive substance worldwide, and its metabolism related with oxidative stress generation. The aim of this work was to evaluate role in alcoholic liver cirrhosis (ALC). This study included 187 patients divided into two groups: ALC, classified according Child-Pugh score, a control group. We determined levels reduced oxidized glutathione (GSH GSSG) GSH/GSSG ratio by an enzymatic method blood. Also, protein carbonyl malondialdehyde (MDA) content were...

10.1155/2016/9370565 article EN cc-by Oxidative Medicine and Cellular Longevity 2016-01-01

Background and Aim . Variceal bleeding is the second most important precipitating factor related to development of episodic hepatic encephalopathy; but date there are no recommendations prevent this complication. The aim study was compare if primary prophylaxis with lactulose or L-ornithine L-aspartate rifaximin, in cirrhotic patients variceal bleeding, better than placebo for avoiding encephalopathy. Methods A randomized, double-blind, placebo-controlled clinical trial (ClinicalTrials.gov...

10.1155/2018/3015891 article EN cc-by Canadian Journal of Gastroenterology and Hepatology 2018-07-10
Jasmohan S. Bajaj Qing Xie Patrick S. Kamath Mark Topazian Peter Hayes and 95 more Aldo Torre Hailemichael Desalegn Ramazan İdilman Mário Reis Álvares‐da‐Silva Jacob George Florence Wong Shiv Kumar Sarin Iliana Mani Haydar Adanır Diederick van Doorn Abha Nagral Anand J. Kulkarni Mohammad Amin Fallahzadeh Bin Xu Hong Tang Araceli Bravo Cabrera Maurício Castillo CE Eapen Ponan Ponan Claude Regis Lah Tongluk Teerasarntipan Elizabeth C. Verna Yu Jun Wong Zhujun Cao Xin Zheng Mohamed Rela Matthew R. Kappus Zeki Karasu Sezgin Barutçu Ewan Forrest Maria Mercedes Rodriguez Gazari J.A. Velarde-Ruiz Velasco Patrícia Momoyo Zitelli Federico Villamil Gustavo Pereira José Luis Pérez-Hernández Adrián Gadano René Malé Velazquez Godolfino Miranda Zazueta Robert N. Gibson Edith Okeke Dibya Lochan Praharaj Tahrima Kayes Mussagy Tarmamade Rahmi Aslan David Bayne Haibing Gao Paul J. Thuluvath Enver Üçbilek Belimi Hibat Allah Beiling Li Jian Wang Dalia Allam Suresh Vasan Venkatachalapathy Ajay Duseja Carlos Alberto Velasco Benítez Stephen M. Riordan Rosemary Faulkes Danielle Adebayo Diana E. Yung Yu Sung Kim Hooi Ling Radha K. Dhiman Yan Yue James Fung Hao Li Peng Hu Lei Wang Yanyun Zhang Liou Wei Lun Al-Tamimi Hala Ashish Kumar Henok Fisseha Liane Rabinowich Yingling Wang Minghua Su Xiaoping Wu Yijing Cai Yanhang Gao Yaodi Zhang Yongfang Jiang Wei Wang Zhiliang Gao Yongchao Xian Xiaozhong Wang Michael Schultheiß Monica Dahiya Nik MA Nik Arsyad K. Rajender Reddy Duarte Rojo Andres Chinmay Bera Scott W. Biggins Fiona Tudehope Ning‐Ping Zhang Leroy R. Thacker Brian Bush Ashok Choudhury

10.1016/s0168-8278(25)00576-8 article EN Journal of Hepatology 2025-05-01
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