Xueyuan Zhang

ORCID: 0000-0003-0159-6996
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About
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Research Areas
  • Esophageal Cancer Research and Treatment
  • Hearing, Cochlea, Tinnitus, Genetics
  • Cancer-related molecular mechanisms research
  • Vestibular and auditory disorders
  • RNA modifications and cancer
  • Gastric Cancer Management and Outcomes
  • Cancer-related gene regulation
  • Sinusitis and nasal conditions
  • Head and Neck Surgical Oncology
  • Circular RNAs in diseases
  • Epigenetics and DNA Methylation
  • Digital Mental Health Interventions
  • Lung Cancer Diagnosis and Treatment
  • Helicobacter pylori-related gastroenterology studies
  • Nasal Surgery and Airway Studies
  • Prostate Cancer Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Antifungal resistance and susceptibility
  • S100 Proteins and Annexins
  • Esophageal and GI Pathology
  • Metabolism and Genetic Disorders
  • Urologic and reproductive health conditions
  • Urinary Bladder and Prostate Research
  • MicroRNA in disease regulation
  • Technology Use by Older Adults

Children's Hospital of Capital Institute of Pediatrics
2024

Fourth Hospital of Hebei Medical University
2017-2024

Hebei Medical University
2017-2024

Children's Hospital of Fudan University
2020-2024

Zunyi Medical University
2022-2024

Wannan Medical College
2023

Guizhou Provincial People's Hospital
2023

Shanghai First People's Hospital
2023

Guizhou University
2023

First Affiliated Hospital of Henan University of Traditional Chinese Medicine
2022

Intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) may protect against mild cognitive impairment (MCI). However, there is still a lack the PUFAs intervention in elderly with MCI China. The aim present study was to investigate effect PUFA supplementation on function Chinese MCI.Eighty six individuals aged 60 years or older were randomly assigned receive either (480 mg DHA and 720 EPA per day, n = 44) placebo (olive oil, 42) capsules. changes functions assessed using Basic Cognitive...

10.3390/nu9010054 article EN Nutrients 2017-01-10

Abstract Background Radioresistance is a major cause of treatment failure in esophageal squamous cell carcinoma (ESCC) radiotherapy, and the underlying mechanisms radioresistance are still unclear. Irradiation (IR) stimulates changes tumor-derived exosome contents, which can be taken up by recipient cells, playing an important role proliferation, cycle apoptosis cells. This study investigated effect IR-induced exosomal high mobility group box 1 (HMGB1) on ESCC Methods Plasma exosomes were...

10.1186/s12967-022-03720-0 article EN cc-by Journal of Translational Medicine 2022-11-05

Abstract Background Prostatic fibrosis, characterized by the accumulation of myofibroblasts and collagen deposition, is closely associated with LUTS may lead to mechanical obstruction urethra. Additionally, Metabolic Syndrome (MetS), central obesity, high blood sugar, lipid metabolism disorders, hypertension, increasingly recognized as a proinflammatory condition linked prostate inflammation. Methods Clinical data from 108 subjects who underwent transurethral resection or bipolar...

10.1186/s12894-024-01413-y article EN cc-by BMC Urology 2024-02-12

Introduction For locally advanced, inoperable esophageal cancer, concurrent chemoradiotherapy (CCRT) becomes the norm. Combining immunotherapy with radiotherapy has been shown to improve efficacy. Circulating tumor DNA (ctDNA) is a strong predictor of effectiveness and recurrence indicative minimal residual disease (MRD). Patients stage II-III squamous cell carcinoma (ESCC) are enrolled in ECMRD-001 trial evaluate changes MRD status before after CCRT combined adjuvant following neoadjuvant...

10.3389/fimmu.2023.1330928 article EN cc-by Frontiers in Immunology 2024-01-11

Loneliness is a growing public health problem that has been exacerbated in vulnerable groups during the COVID-19 pandemic. Social support interventions have shown to reduce loneliness, including when delivered through technology. Digital humans are new type of computer agent show promise as supportive peers care. For digital be effective and engaging persons, it important they develop closeness with people. Closeness can increased by emotional expressiveness, particularly female...

10.2196/30624 article EN cc-by Journal of Medical Internet Research 2021-10-05

Background Acute liver failure (ALF) can be a primary presentation of Wilson disease (WD). Mortality rates are high in WD with ALF (WDALF). Predictions mortality WDALF vary by model and sometimes contradictory, perhaps because few patients studied or diagnoses questionable. Aim To determine the outcomes among well-documented assess performance this cohort. Methods We reviewed medical records our pediatric (n = 41 over 6-years-old, single-center retrospective study) compared seven prognostic...

10.12998/wjcc.v9.i14.3273 article EN World Journal of Clinical Cases 2021-04-29

Esophageal cancer is a common malignant disease that generally treated with radiotherapy. High mobility group box 1 (HMGB1) plays an essential role in tumor cell proliferation, migration, and cycle progression. Here, we aimed to clarify the effects of HMGB1 on radioresistance esophageal squamous carcinoma (ESCC) lines patient survival. We performed immunohistochemistry for biopsy samples 39 stage I-III ESCC patients grouped by expression status. Then, 1-, 3-, 5-, 10-year overall survival...

10.7150/jca.73761 article EN cc-by-nc Journal of Cancer 2022-01-01

Conclusions: The long-term quality of life adolescents with chronic rhinosinusitis improved significantly after functional endoscopic sinus surgery (FESS), and showed certain benefits for adolescent patients. selection appropriate patients may further improve the surgical outcomes life. Objective: To analyze in (12–18 years) surgery, to evaluate value Methods: From 2003 2008, 729 sinusitis underwent our department; 270 these were included study. Their was assessed before within 3–8 years...

10.3109/00016489.2012.668709 article EN Acta Oto-Laryngologica 2012-06-05

Backgroud/Aims: The effects of rapamycin (RPM) on wound healing have been previously studied. However, reciprocal contradictory data reported, and the underlying mechanism remains unclear. This study aims to uncover differential role RPM in regulation explore possible mechanism. Methods: C57BL/6J mice epidermal cells were treated with different doses RPM. re-epithelialization was observed by hematoxylin eosin (HE) staining. expression IL-15 IGF-1 detected immunohistochemistry quantitative...

10.1159/000479443 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2017-01-01
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