A5084561895- Enzyme Catalysis and Immobilization
- Enzyme Production and Characterization
- Fungal Biology and Applications
- Microbial Metabolic Engineering and Bioproduction
- Mycotoxins in Agriculture and Food
- Plant Pathogens and Fungal Diseases
- Biochemical and Structural Characterization
- Microbial Metabolites in Food Biotechnology
- Plant biochemistry and biosynthesis
- Antibiotic Resistance in Bacteria
- Biofuel production and bioconversion
- Mesoporous Materials and Catalysis
- Liver Diseases and Immunity
- Bacterial Genetics and Biotechnology
- Liver Disease Diagnosis and Treatment
- Enzyme-mediated dye degradation
- Bioinformatics and Genomic Networks
- Monoclonal and Polyclonal Antibodies Research
- Galectins and Cancer Biology
- scientometrics and bibliometrics research
- CRISPR and Genetic Engineering
- Carbohydrate Chemistry and Synthesis
- Biochemical and Molecular Research
- Probiotics and Fermented Foods
- Biochemical Acid Research Studies
UiT The Arctic University of Norway
2015-2017
Oslo University Hospital
2016
University of Oslo
2015-2016
Chalmers University of Technology
2010-2013
Technical University of Denmark
2010
Background Metabolic engineering is an attractive approach in order to improve the microbial production of drugs. Triterpenes a chemically diverse class compounds and many among them are interest from human health perspective. A systematic experimental or computational survey all feasible gene modifications determine genotype yielding optimal triterpene phenotype laborious time-consuming process. Methodology/Principal Findings Based on recent genome-wide sequencing Saccharomyces cerevisiae...
Chitin, a polymer of β(1-4)-linked N-acetylglucosamine found in e.g. arthropods, is valuable resource that may be used to produce chitosan and chitooligosaccharides, two compounds with considerable industrial biomedical potential. Deacetylating enzymes tailor the properties chitin its derived products. Here, we describe novel CE4 enzyme originating from marine Arthrobacter species (ArCE4A). Crystal structures this deacetylase were determined, without bound chitobiose [(GlcNAc)2], refined 2.1...
Molecular docking is the most commonly used technique in modern drug discovery process where computational approaches involving algorithms are to dock small molecules into macromolecular target structures. Over recent years several evaluation studies have been reported by independent scientists comparing performance of programs using default 'black box' protocols supplied software companies. Such be considered carefully as can tweaked towards optimum selecting parameters suitable for...
Background Identifying causative biological networks associated with relevant phenotypes is essential in the field of systems biology. We used ferulic acid (FA) as a model antioxidant to characterize global expression programs triggered by this small molecule and decipher transcriptional network controlling phenotypic adaptation yeast Saccharomyces cerevisiae. Methodology/Principal Findings By employing strict cut off value during gene data analysis, 106 genes were found be involved cell...
Background Feruloyl esterases (FAEs) are important biomass degrading accessory enzymes due to their capability of cleaving the ester links between hemicellulose and pectin aromatic compounds lignin, thus enhancing accessibility plant tissues cellulolytic hemicellulolytic enzymes. FAEs have gained increased attention in area biocatalytic transformations for synthesis value added with medicinal nutritional applications. Following increasing on these enzymes, a novel descriptor based...
The gene expression and secretion of fungal lignocellulolytic enzymes are tightly controlled at the transcription level using independent mechanisms to respond distinct inducers from plant biomass. An advanced systems-level understanding transcriptional regulatory networks is required rationally engineer filamentous fungi for more efficient bioconversion different types biomass.In this study we focused on ten chemically defined drive cellulases, hemicellulases accessory in model fungus...
Abstract One of the most intriguing groups enzymes, feruloyl esterases (FAEs), is ubiquitous in both simple and complex organisms. FAEs have gained importance biofuel, medicine food industries due to their capability acting on a large range substrates for cleaving ester bonds synthesizing high-added value molecules through esterification transesterification reactions. During past two decades extensive studies been carried out production partial characterization from fungi, while much less...
Watch the VIDEO of presentation.As per standard definition, "Peer review is critical assessment manuscripts submitted to journals by experts who are not part editorial staff". The reviewers generally researchers employed in institutions where research conducted, for example universities and other academic institutions. Peer has rarely been a focus university's management or administration. initiated managed publishers doing peer reviewing work. A recent study at University Tromsø (UiT)...