Mark Looseley

ORCID: 0000-0003-0170-8900
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About
Contact & Profiles
Research Areas
  • Wheat and Barley Genetics and Pathology
  • Plant Disease Resistance and Genetics
  • Plant Pathogens and Fungal Diseases
  • Mycotoxins in Agriculture and Food
  • Crop Yield and Soil Fertility
  • Biofuel production and bioconversion
  • Plant Pathogens and Resistance
  • Genetic Mapping and Diversity in Plants and Animals
  • Agriculture, Plant Science, Crop Management
  • Chromosomal and Genetic Variations
  • Genetics and Plant Breeding
  • Fermentation and Sensory Analysis
  • Plant-Microbe Interactions and Immunity
  • Plant Reproductive Biology
  • Cancer-related molecular mechanisms research
  • RNA and protein synthesis mechanisms
  • Aquaculture Nutrition and Growth
  • Botany, Ecology, and Taxonomy Studies
  • RNA modifications and cancer
  • Yeasts and Rust Fungi Studies
  • Plant Taxonomy and Phylogenetics
  • Genetic diversity and population structure
  • Genomics and Phylogenetic Studies
  • Genetic and phenotypic traits in livestock
  • Animal Genetics and Reproduction

James Hutton Institute
2011-2023

University of Edinburgh
2006

Genomics is increasingly applied in breeding programmes for farmed fish and shellfish species around the world. However, current applications do not include information on genome functional activity, which can enhance opportunities to predict relationships between genotypes phenotypes hence increase accuracy of selection. Here, we review prospects improving aquaculture practises through uptake genomics data light EU Horizon 2020 project AQUA-FAANG: ‘Advancing European Aquaculture by Genome...

10.1016/j.aquaculture.2024.740589 article EN cc-by Aquaculture 2024-01-17

We analyzed the complete genome sequence of Arabidopsis thaliana and data from 83 genes in outcrossing A. lyrata, to better understand role gene expression on strength natural selection synonymous replacement sites Arabidopsis. From tRNA abundance, we find a good concordance between codon preferences relative abundance isoaccepting tRNAs genome, consistent with models translational selection. Both EST-based new quantitative measures (MPSS) suggest that derived information are more strongly...

10.1093/molbev/msh191 article EN Molecular Biology and Evolution 2004-06-17

Genomic selection can accelerate genetic progress in aquaculture breeding programmes, particularly for traits measured on siblings of candidates. However, it is not widely implemented most species, and remains expensive due to high genotyping costs. Genotype imputation a promising strategy that reduce costs facilitate the broader uptake genomic programmes. predict ungenotyped SNPs populations genotyped at low-density (LD), using reference population high-density (HD). In this study, we used...

10.3389/fgene.2023.1194266 article EN cc-by Frontiers in Genetics 2023-05-11

We investigated DNA sequence diversity for loci on chromosomes 1 and 2 in six natural populations of Arabidopsis lyrata tested the role selection structuring genomewide patterns variability, specifically examining effects recombination rate levels silent polymorphism. In contrast with theoretical predictions from models genetic hitchhiking, maximum-likelihood-based analyses divergence do not suggest reduction region suppressed near centromere chromosome 1, except a single population Russia,...

10.1534/genetics.106.062588 article EN Genetics 2006-09-02

Historical malting quality data was collated from UK national and recommended list trial used in a GWAS. 25 QTL were identified, with the majority spring barley cultivar sets. In Europe, most economically significant use of is production malt for brewing distilling industries. As such, selection traits related to great commercial interest. order study genetic basis variation cultivars, historical set trials period 1988 2016. This estimate variety means 20 451 407 winter cultivars. Genotypes...

10.1007/s00122-020-03618-9 article EN cc-by Theoretical and Applied Genetics 2020-06-06

Abstract Hybridization is an important evolutionary factor in the diversification of many plant and animal species. Of particular interest that historical hybridization resulting origin new species or introgressants has occurred between now geographically separated by great distances. Here, we report Senecio massaicus , a tetraploid native to Morocco Canary Islands, contains genetic material two distinct, lineages: Mediterranean lineage mainly southern African lineage. A time‐calibrated...

10.1111/j.1365-294x.2011.05399.x article EN Molecular Ecology 2011-12-15

The phenolic acids, ferulic acid and p -coumaric acid, are components of plant cell walls in grasses, including many our major food crops. They have important health-promoting properties grain, influence the digestibility biomass for industrial processing livestock feed. Both acids assumed to be critical wall integrity at least, is cross-linking components, but role unclear. Here we identify alleles a BAHD p- coumaroyl arabinoxylan transferase, HvAT10 , as responsible natural variation...

10.3389/fpls.2023.1095862 article EN cc-by Frontiers in Plant Science 2023-05-10

Diastatic Power (DP) is an important quality trait for malt used in adjunct brewing and distilling. Substantial genetic variation DP exists within UK elite barley cultivars, but breeding progress has been slow due to the limited demand, compared overall market, difficulties assessing DP. Estimates of (taken from recommended national list trials between 1994 2012) a collection winter spring varieties were identify contrasting sets high low varieties. DNA samples pooled exome capture...

10.3389/fpls.2017.01566 article EN cc-by Frontiers in Plant Science 2017-09-12

Rhynchosporium is one of the main biotic stresses on barley production worldwide. A set 312 spring accessions was tested in four different locations over 3 years, to identify novel genetic resistances rhynchosporium and explore allelic diversity for resistance genes present this global germplasm collection. High-density genotypes from exome capture RNA-seq were used conduct high-resolution association mapping. Seven quantitative trait loci (QTL) detected, including Rrs2 region, amongst five...

10.3390/agronomy12040782 article EN cc-by Agronomy 2022-03-24

Microbial infections of crop plants present an ongoing threat to agricultural production. However, in recent years, we have developed a more nuanced understanding the ecological role microbes and how they interact with plants. This includes appreciation influence physiology environmental conditions on expression disease symptoms, importance non-pathogenic host pathogens, capacity for act as hosts human pathogens. Alongside this now variety tools available identification quantification...

10.3390/agronomy4020302 article EN cc-by Agronomy 2014-06-24

Phenolic acids in cereal grains have important health-promoting properties and influence digestibility for industrial or agricultural uses. Here we identify alleles of a single BAHD p- coumaroyl arabinoxylan transferase gene, HvAT10 , as responsible the natural variation cell wall-esterified p -coumaric ferulic acid whole grain collection cultivated two-row spring barley genotypes. We show that is rendered non-functional by premature stop codon mutation approximately half genotypes our...

10.1101/2020.12.21.423816 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-12-22
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