A5013368667- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Surgical Oncology
- Neuroendocrine Tumor Research Advances
- Tumors and Oncological Cases
- Lymphatic System and Diseases
- Tracheal and airway disorders
- Oral health in cancer treatment
- Head and Neck Anomalies
- Esophageal Cancer Research and Treatment
- Cleft Lip and Palate Research
- Venous Thromboembolism Diagnosis and Management
- Ear and Head Tumors
- Diversity and Career in Medicine
- Nausea and vomiting management
- Voice and Speech Disorders
- Spine and Intervertebral Disc Pathology
- Case Reports on Hematomas
- Skin Protection and Aging
- Esophageal and GI Pathology
- Thyroid and Parathyroid Surgery
- Diagnosis and Treatment of Venous Diseases
- Advancements in Transdermal Drug Delivery
- Dysphagia Assessment and Management
West Virginia University
2017-2025
University of Ottawa
2013-2014
Ottawa Hospital
2013-2014
The optimal approach for treatment deescalation in human papillomavirus (HPV)-related oropharyngeal squamous cell carcinomas (OPSCCs) is unknown.To assess a primary radiotherapy (RT) vs transoral surgical (TOS) HPV-related OPSCC.This international, multicenter, open-label parallel-group phase 2 randomized clinical trial was conducted at 9 tertiary academic cancer centers Canada and Australia enrolled patients with T1-T2N0-2 p16-positive OPSCC between February 13, 2018, November 17, 2020....
The purpose of this study is to test the hypothesis that increasing force applied on skin by Cutometer MP580 probe will result in a decrease elasticity measures. Specifically, assessed intrinsic weight plus addition light mass (10 g and 20 g), moderate (50 100 g) high (200 500 Primary outcome measures Uv, Ur, Uf, Ue Ua, along with calculated Uv/Uf, Ua/Uf Ur/Uf were under each loading condition. A general linear model ANOVA repeated was used assess for differences measure between Thirty-two...
Evaluate factors associated with treatment delays and their effect on survival in laryngeal squamous cell carcinoma.Retrospective cohort study.National Cancer Database.Patients receiving primary radiation or surgery for carcinoma were included from 2004 to 2017. The outcomes the diagnosis-to-treatment interval (DTI) 5-year survival. Variables of prolonged DTI (>30 days) assessed via logistic regression models. Survival was then through Cox proportional hazards Candidate variables both age,...
Importance Postoperative radiation therapy for close surgical margins in low- to intermediate-grade salivary carcinomas lacks multi-institutional supportive evidence. Objective To evaluate the oncologic outcomes and with positive margins. Design, Setting, Participants The American Head Neck Society Salivary Gland Section conducted a retrospective cohort study from 2010 2019 at 41 centers. Margins were classified as R0 (negative), R1 (microscopically positive), or R2 (macroscopically...
The purpose of our study is to test the feasibility transoral thyroid chondrolaryngoplasty using a similar approach thyroidectomy. This would allow for gender‐affirming surgery while avoiding an external neck scar. We carried out cadaveric in anatomy laboratory at academic center. Five fresh cadavers were used this study. lower oral vestibular incision, along with retractors and endoscope dissect gain access laryngeal prominence cartilage. Portions then removed scissors achieve satisfactory...
Objective To describe the resident experience with respect to key indicator cases for each year of training. Study Design Multi‐institution, cross‐sectional assessment. Methods Using an electronic survey, current otolaryngology residents were solicited complete a survey regarding their experiences that point. The was sent this cohort in winter 2017–2018. Results Three hundred and three responded, 293 completing survey. Twenty‐three percent PGY1, 19% PGY2, 21% PGY3, 18% PGY4, PGY5 or higher....
There is limited data independently assessing the optimal use of Cutometer MPA580. The purpose this study to test hypothesis that assessment elastic recoil significantly different when utilizing two probe placement protocols. In protocol A, four trials were performed, in which was removed from skin between trials. B, not Fifty-four patients enrolled and all completed testing. When elasticity (Ua/Uf), inter-class correlation 0.83 for A 0.48 B (p < 0.001). no significant difference individual...
The use of pre-operatively applied topical tissue expansion tapes have previously demonstrated increased rates primary closure radial forearm free flap donor sites. This is associated with a reduced cost care as well improved cosmetic appearance the site. Unfortunately, little known about biomechanical changes these cause in skin. study tested hypothesis that topically will result an increase skin pliability patients undergoing surgery.Twenty-four scheduled for head and neck surgery...
Objective: Evaluate the effects of operative time and 2 team approach on complications after soft tissue free flap reconstruction for oral tongue cancer. Methods: Patients with oncologic glossectomy myocutaneous or fasciocutaneous were included from 2015 to 2018 American College Surgery National Surgical Quality Improvement Program. The primary predictive variables assessed approach; control age, sex, body mass index (BMI), 5-question-modified frailty (mFI-5), Society Anesthesiologists (ASA)...
Branchial anomalies are heterogeneous congenital malformations that form secondary to incomplete closure of pharyngeal clefts and pouches. There have been no reports branchial cleft cysts causing carotid artery compression hypertension. We report a large cyst suspected hypertension from compression.
Objectives Treatment for advanced head and neck cancers typically includes surgery followed by radiation therapy (RT). Radiation‐induced xerostomia is a common sequela of these treatments. The modified submandibular gland transfer (M‐SGT) procedure was developed to decrease in the treatment oral cavity cancer sparing one (SMG) from radiation. This study's objectives were to: 1) elucidate radiation‐sparing capacity M‐SGT, 2) study xerostomia‐reducing potential M‐SGT based on University...
Background . Undifferentiated anaplastic carcinoma rarely develops from chronic hyperthyroidism. Although acute hyperthyroidism can develop prior to transformation, was thought be a protective measure against thyroid malignancy. Methods A 79-year-old female presented acutely the hospital with dyspnea. She had been taking methimazole for due toxic nodules, previously biopsied as benign. Upon admission, imaging showed tracheal compression, requiring total thyroidectomy tracheostomy airway...
Transoral robotic and laser surgery is rising in popularity due to the increasing incidence of Human Papilloma Virus (HPV) related oropharyngeal cancer. However, adequate exposure tongue base remains a major hurdle many cases. This study introduces novel surgical technique called Floor Mouth Window, which can be used improve at time transoral surgery.This preclinical anatomic cadaver study. Seven fresh cadavers were for this Exposure was compared between conventional mouth gags -...
Background: The safety of preoperative chemoprophylaxis for deep venous thrombosis (DVT) prevention in patients undergoing head and neck oncologic surgery with free tissue transfer (HNS-FTT) remains undetermined. Methods: Retrospective chart review HNS-FTT receiving versus not intraoperative subcutaneous enoxaparin (Px-LMWH) was performed. Outcomes included estimated blood loss (EBL), hematoma, flap compromise, DVT or pulmonary embolus (PE). Fisher’s exact test Wilcoxon Rank Sum were...
Abstract Background Tumor‐specific molecular imaging in head and neck squamous cell carcinoma (HNSCC) is not well established. Somatostatin receptors (SSTRs) are found solid tumors, including HNSCC. 68 Ga‐DOTATATE, a commercially available radionuclide that binds SSTRs, may have utility Methods Patients with HNSCC received pretreatment 18 F‐FDG‐PET/CT Ga‐DOTATATE. Imaging was compared for concordance. When available, surgical resection specimens were to findings. Historic tumor assessed both...
Importance: Operative laryngoscopy is a commonly performed ambulatory procedure in patients with significant co-morbidity. Optimal anesthetics for surgical exposure rapid return to baseline after the enhances postoperative patient safety. Objective To determine whether sugammadex hastens recovery undergoing operative under general anesthesia rocuronium-induced paralysis. Design Prospective clinical intervention randomized single-blinded, single-center study an academic tertiary care center....
e17568 Background: The increasing incidence of HPV associated oropharyngeal cancer has sparked interest in minimally invasive transoral surgery as a primary treatment modality. However, adequate surgical exposure and access to the tongue base is difficult achieve. Many complex oral retraction systems have been developed attempt solve this problem but none work consistently or efficiently. Methods: This cadaveric study introduces floor mouth window – simple adjunctive procedure done at time...