A5056852522- Cervical Cancer and HPV Research
- Virus-based gene therapy research
- Poxvirus research and outbreaks
- Ear and Head Tumors
- Vascular Malformations and Hemangiomas
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Cancer Studies
- Vascular Malformations Diagnosis and Treatment
- Dysphagia Assessment and Management
- Childhood Cancer Survivors' Quality of Life
- Tumors and Oncological Cases
- Smoking Behavior and Cessation
- Viral-associated cancers and disorders
- Airway Management and Intubation Techniques
- Meningioma and schwannoma management
- Nasal Surgery and Airway Studies
- Pelvic floor disorders treatments
- Reconstructive Surgery and Microvascular Techniques
- Sleep and related disorders
- Catalysis for Biomass Conversion
- Bipolar Disorder and Treatment
- Breast Lesions and Carcinomas
- Herpesvirus Infections and Treatments
- Voice and Speech Disorders
- Lignin and Wood Chemistry
Penn State Milton S. Hershey Medical Center
2023-2025
Pennsylvania State University
2022-2025
Vascular Institute of New York
2022-2025
Google (United States)
2024
Hershey (United States)
2024
Lenox Hill Hospital
2022
University of Michigan
2019-2020
Ann Arbor Center for Independent Living
2019
Herein, an organocatalytic method for photochemical C–O bond cleavage of lignin systems is reported. The use photochemistry enabled fragmentation the β-O-4 linkage, primary linkage in lignin, provides products good to high yields. approach was merged with reported oxidation conditions a one-pot, two-step platform without any intermediary purification, suggesting its fidelity. future utility illustrated by applying visible light-mediated protocol continuous flow processing.
Abstract Objective Perioperative tobacco use is associated with poor wound healing postoperative complications. The purpose of this study to serum cotinine as a measure consumption evaluate complication rates and outcomes in patients undergoing septorhinoplasty procedures. Study Design Prospective study. Setting Tertiary care academic center. Methods Patients >18 years old from December 2017 January 2023 were included. Serum levels obtained on the day surgery. Preoperative nasal...
<p>Figure S2. WGS and anchored PCR analysis of chromosomal region adjacent to viral integration sites in transformed keratinocytes.</p>
<div>Abstract<p>Approximately 70% of oropharyngeal squamous carcinomas (OPSCC) are associated with human papillomavirus (HPV). Although patients HPV-positive (HPV<sup>+</sup>) tumors generally have better outcomes than those HPV-negative tumors, a subset HPV<sup>+</sup> positive do poor outcomes. Our previous work suggested that integrated virus exhibit significantly greater genome-wide genomic instability only episomal viral genomes, and OPSCC genomes had...
<p>Figure S1. Long Range Anchored PCR</p>
Background: Auricular arteriovenous malformations (AVMs) are rare vascular anomalies, being the second most prevalent after cheek AVMs. Their management presents challenges. Objective: We aim to explore clinical presentation of ear AVMs, highlighting a unique pattern focal auricular AVM. Methods: A retrospective review was conducted over 7 years, focusing on patients diagnosed with Exclusions included non-AVM diagnosis, adjacent anatomical site extensions, and lack patient information or...
Importance Postoperative radiation therapy for close surgical margins in low- to intermediate-grade salivary carcinomas lacks multi-institutional supportive evidence. Objective To evaluate the oncologic outcomes and with positive margins. Design, Setting, Participants The American Head Neck Society Salivary Gland Section conducted a retrospective cohort study from 2010 2019 at 41 centers. Margins were classified as R0 (negative), R1 (microscopically positive), or R2 (macroscopically...
Approximately 70% of oropharyngeal squamous carcinomas (OPSCC) are associated with human papillomavirus (HPV). While HPV-positive (HPV+) OPSCC responds better to standard therapies and patients HPV+ tumor generally have outcomes than those HPV-negative (HPV-) tumors, a subset do poor outcomes. Our previous work suggested that tumors integrated virus exhibit significantly greater genome wide genomic instability only episomal viral genomes had To explore the causal relation between integration...
Soft-tissue loss is expected after resection of large vascular lesions. Autologous fat transfer improves asymmetries; however, systematic outcomes are not previously described for anomaly reconstruction.Retrospective chart review from 2012 to 2015 included patients receiving autologous transfers soft-tissue defects during or following surgery at a tertiary care center. Patients received dermal en bloc grafts, lipoaspirates, both. Pre- and postoperative photographs were blindly reviewed by 3...
Purpose: The purpose of this study is to discuss the feasibility developing, and challenges implementing, a structured dysphagia program in rural patient population with preliminary data. Method: Dysphagia Pathway Program (DPP) standardized, prophylactic swallow therapy for head neck cancer patients initiated 2019 as multidisciplinary approach at Penn State Hershey Medical Center. An interrupted time series was conducted comparing nutritional status pre- postimplementation DPP. Data were...
Objective: The purpose of this study is to evaluate the postoperative urinary complications and optimal timing foley catheter removal in patients who underwent free flap reconstructive surgery for head neck pathology. Methods: A retrospective case-control at a single institution between January 2009 December 2021 was conducted. Patient risk factors retention (POUR) were analyzed. Fisher Exact Wilcoxon Rank Sum tests used rates replacement, straight catheterization, catheter-associated tract...
Differences in treatment outcomes between community or academic centers are incompletely understood.
Management of clinically negative necks (cN0) in oral cavity (OCSCC) and oropharyngeal (OPSCC) squamous cell carcinoma (SCC) has evolved over time. Historically, the neck been managed with elective dissection (END) or observation, but more recently sentinel lymph node biopsy (SLNB) emerged as a technique to detect occult metastases. In this review, we will discuss role SLNB early-stage OCSCC management OPSCC.
Early evaluation and treatment of periorbital infantile hemangiomas (POIH) were associated with lower rates ophthalmological complications.
This study aims to analyze the distribution of otolaryngologists between urban and rural counties in Pennsylvania.
Abstract Approximately 70% of oropharyngeal squamous carcinomas (OPSCC) are associated with human papillomavirus (HPV). Although patients HPV-positive (HPV+) tumors generally have better outcomes than those HPV-negative tumors, a subset HPV+ positive do poor outcomes. Our previous work suggested that integrated virus exhibit significantly greater genome-wide genomic instability only episomal viral genomes, and OPSCC genomes had To explore the causal relation between integration instability,...
Background: Periorbital infantile hemangiomas (POIHs) are associated with a high incidence of visual complications. Objective(s): To analyze the sites predilection POIHs and to determine whether certain require earlier intervention due their higher rate Methods: A retrospective case series study was conducted on patients from two tertiary care centers for 25 years. The location determined clinical photographs, medical records, radiological studies. presence or absence anisometropic...
Phrenic nerve schwannomas of the head and neck are exceedingly rare pathologies that can present as an asymptomatic mass. Surgery is definitive treatment, a conservative surgical approach preferred if benign pathology suspected.