A5012192511- Traditional Chinese Medicine Analysis
- Phytochemistry and Biological Activities
- Computational Drug Discovery Methods
- Chromatography in Natural Products
- Flavonoids in Medical Research
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Essential Oils and Antimicrobial Activity
- Bioactive natural compounds
- Phytochemicals and Antioxidant Activities
- Phytochemicals and Medicinal Plants
- Allelopathy and phytotoxic interactions
- Spectroscopy and Chemometric Analyses
- Ginseng Biological Effects and Applications
- Medicinal Plant Pharmacodynamics Research
- Phytochemistry and Bioactivity Studies
- Ziziphus Jujuba Studies and Applications
- Metabolomics and Mass Spectrometry Studies
Tianjin University of Traditional Chinese Medicine
2021-2025
Introduction Scutellariae Radix (SR), derived from the root of Scutellaria baicalensis Georgi, is a traditional Chinese medicine (TCM) for clearing heat and cooling blood. It has been used as herbal popular functional food in Asian countries today. Methods In this study, UPLC-Q-TOF-MS was first employed to identify chemical components ethanol extract SR. Then, extraction process optimized using star point design-response surface methodology. Fingerprints different batches processed products...
Plantago, also known as plantain, has been used a traditional herb in Asia for centuries to treat urinary tract inflammation and kidney disease. Recently, there increasing interest its potential applications the food industry. In China, are two common species of, namely Plantago asiatica L.(PAL) P. depressa Willd.(PDW), which not distinguished folk clinical practices, leading safety efficacy risks plantago applications. The objective of this study is establish reliable method differentiating...
The characteristics of chemical components or groups in traditional Chinese medicines (TCMs) determine their clinical efficacy. Quality markers (Q-markers) is great significance for standardizing the quality control system TCM.We aimed to develop a new strategy discover potential Q-markers TCM by integrating chemometrics, network pharmacology, and molecular docking, using Centipeda minima (also known as ebushicao [EBSC]) an example.First, fingerprints different batches EBSC its counterfeit...
Aurantii Fructus (AF) and Immaturus (AFI) are distinct herbs outlined by the Chinese Pharmacopoeia. They sourced from same plant but harvested at different times, resulting in differences efficacy. It is important to avoid mixing them clinically distinguish between two. Furthermore, dissimilar cultivation conditions may cause variability quality of herbs, so it vital differentiate drugs origins. In this study, two plants, AF AFI provinces, were comparatively analyzed based on High...
Panax Japonicus (PJ) is a widely used Chinese herbal medicine, functional food and tonic. However, its origin has great influence on the quality of PJ, with increasing demand for fake inferior products, such as Stipuleanatus (PS), often appear. The identification authenticity PJ critical ensuring quality, safety effectiveness drugs.Proposing strategy to identify origin, authenticity, using HPLC fingerprints, chemometrics, network pharmacology.The chromatographic fingerprint method was...
Centipeda minima (L.) A. Br. et Aschers, known as Ebushicao (EBSC) in Chinese, has long been used traditional Chinese medicine for dispelling wind, clearing orifices, detoxification, and swelling. Although the use of EBSC involves whole plant, during harvesting processing, separation stems, leaves, flowers, roots often occurs. However, there are few studies on its medicinal parts.A strategy combining high-performance liquid chromatography (HPLC) fingerprinting multivariate classification...
Cynomorium songaricum is a commonly used medicinal and culinary plant renowned for its effects in tonifying kidney yang, as well nourishing essence blood. Consequently, it has garnered considerable attention within the fields of pharmacology chemistry. However, given distinct geographical distribution C. resources, establishing an accurate analytical method to differentiate origin becomes indispensable ensuring quality efficacy. In this study, high-performance liquid chromatography (HPLC)...
The quality of the root bark Morus alba L. (SBP) herbs currently circulating in market is variable. In order to ensure clinical effectiveness, a high-performance liquid chromatography (HPLC) fingerprinting method combined with chemical pattern recognition should be established control SBP herbs. differences 23 batches were analyzed by exploratory cluster analysis based on shared fingerprint peak data, and results indicated that processing remove cork layer from materials an important...
Physalis alkekengi L. var. franchetii (PALF) is a traditional Chinese medicine, which well known for its antimicrobial, anti-inflammatory, antipyretic, and expectorant properties. Its fruits fruiting calyxes are used as dietary supplements herbs in China. However, the quality of uneven, it prone to getting moldy or moth-eaten during storage. High-performance liquid chromatography (HPLC) fingerprints multivariate chemometric methods were combined evaluate quality, three representative...
Cuscuta chinensis Lam. is a medicinal herb widely used in Chinese medicine. However, it often replaced illegally with extracts of japonica Choisy. Thus, there need to be able distinguish between samples from these two species. In this study, combination chemical HPLC fingerprinting and chemometrics was compare identify C. japonica. The composition the determined by fingerprinting. These results were then analyzed chemometrics, namely hierarchical clustering analysis, principal component both...