A5006924920- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Head and Neck Surgical Oncology
- Cancer Diagnosis and Treatment
- Tumors and Oncological Cases
- Oral and Maxillofacial Pathology
- Tracheal and airway disorders
- Reconstructive Surgery and Microvascular Techniques
- Thyroid and Parathyroid Surgery
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Anomalies
- Lung Cancer Treatments and Mutations
- Airway Management and Intubation Techniques
- Bone Tumor Diagnosis and Treatments
- Voice and Speech Disorders
- Cancer and Skin Lesions
- Vascular Malformations and Hemangiomas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Endometrial and Cervical Cancer Treatments
- Lymphoma Diagnosis and Treatment
- Oral health in cancer treatment
- Facial Nerve Paralysis Treatment and Research
- Vascular Tumors and Angiosarcomas
- Cancer-related molecular mechanisms research
Universidade Federal de Santa Catarina
2025
Instituto Nacional do Câncer
2005-2021
Universidade Estadual de Campinas (UNICAMP)
2021
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2021
Universidade de São Paulo
2009
Universidade Federal de Uberlândia
2009
Universidade do Estado do Rio de Janeiro
2007
Consorzio Interuniversitario Nazionale La Chimica Per L'Ambiente
1999-2006
Instituto Nacional del Cáncer
2006
Pontifical Catholic University of Rio de Janeiro
2005
To analyze the factors in parotid malignant epithelial tumors influencing recurrences and disease-specific survival.We retrospectively reviewed files of 150 patients treated at our institution, from 1974 to 1998. Twenty-four were not by surgery excluded this study. The remaining 126 with 74 had postoperative radiotherapy. Thirty-three parotidectomy plus neck dissection. Neck lymph node metastasis was found 22 patients, 5 occult metastasis, 4 periparotid nodes metastasis. mean age 49 years...
A retrospective study was undertaken of patients with T1N0M0 squamous cell carcinoma the oral tongue and floor mouth who underwent surgical treatment between 1985 1995. Evaluation two groups (neck dissection versus observation) made according to management neck. Results were obtained regarding presence occult metastases, recurrence in neck, failure, results salvage treatment, disease‐free survival. Forty‐nine treatment: 25 resection primary 24 plus neck dissection. Overall incidence regional...
To analyze the therapeutic implications of distribution neck metastases (NM) in patients with squamous cell carcinoma (SCC) tongue and floor mouth (FOM).From January 1987 through December 1997, 339 previously untreated T1-2 N0 M0 SCC FOM underwent primary surgical treatment our institution. A retrospective review pathology reports outcome these was made to ascertain prevalence NM. Patients were grouped by clinical status at time dissection: elective dissection (END) NO subsequent (STD)...
To evaluate the results of standardized treatment esthesioneuroblastoma (ENB) during a 17-year period and to identify pertinent factors for clinical outcome.Review radiographic data retrospectively staging ENB according 3 systems: Kadish, Biller, Dulguerov Calcaterra.Hospital do Cancer I-Instituto Nacional de Cancer, Rio Janeiro, Brazil.Thirty-six patients with histologically confirmed treated between January 1, 1983, December 31, 2000; 35 fulfilled study inclusion criteria.Treatment...
Nasopharyngeal cancer (NPC) is a distinct form of the upper respiratory or digestive tract in which epidemiologic features, origin, histopathologic types, treatment, and prognosis are different from those associated with other malignant neoplasms this anatomical area. Recent publications have demonstrated advantage aggressive multimodality treatment for advanced NPC.To evaluate results standardized NPC during 11 years to identify pertinent factors clinical outcome.Between January 1, 1989,...
The incidence of pediatric differentiated thyroid carcinoma (DTC) has been rising in recent years, and the main risk factors for recurrence are lymph node distant metastasis at diagnosis. Other clinical features remain unclear, such as impact age, sex, puberty. Furthermore, until now, this population treated using same strategies used to treat adults. In 2015, American Thyroid Association (ATA) published first guidelines targeted age group. aims study were investigate prognostic early...
Supracricoid laryngectomy with cri-cohyoidoepiglottopexy (CHEP) is a conservative surgical procedure indicated in selected cases of advanced glottic carcinoma.This study review our experience 43 patients T3/T4 squamous cell carcinoma who underwent CHEP institution. All but two selective neck dissections. were staged on the basis 2002 TNM classification. Rates recurrence and death estimated by Kaplan-Meier method.The 5-year disease-specific survival relapse-free rates 78% 83%, respectively....
Sublingual gland tumors are rare, although frequently malignant. This study describes the clinicopathologic features and treatment results reviews literature.Thirteen cases treated between 1996 2007 were reviewed with interest on clinical, pathologic, therapeutic information. Survival data calculated by Kaplan-Meier method.Malignancies represented 92.3% of cases. Adenoid cystic carcinoma was most common malignant type (66.7%). Most patients (83.3%) presented in advanced pathologic TNM stages...
Abstract Background The aim was to collate and contrast patient concerns from a range of different head neck cancer follow‐up clinics around the world. Also, we sought explore relationship, if any, between responses inventory (PCI) overall quality life (QOL). Methods Nineteen units participated with intention including 100 patients per site as close consecutive series possible in order minimize selection bias. Results There were 2136 median total number PCI items selected 5 (2‐10). “Fear...
Background: Laryngeal carcinoma involving anterior vocal commissure (AVC) represents a great challenge for staging and treatment. Objectives: To compare laryngoscopy computed tomography (CT) scan efficiency in tumors extending to the AVC. We also analyzed helicoidal axial CT accuracy recognizing this larynx subregion invasion. Material And Methods: Fifty-two glottic supraglottic laryngeal squamous cell patients with tumoral extension AVC were prospectively studied from August 2001 2003 at...
We retrospectively reviewed the medical charts of 57 patients with advanced malignant cutaneous tumors involving anterior skull base who underwent combined craniofacial resection in our department from January 1, 1981, to December 31, 1994.The data regarding histological results, demographic aspects, clinical presentation, previous treatment, extent disease, surgical procedure, type reconstruction, complications, and follow-up were analyzed using chi 2 method. Survival analysis was performed...
To assess the oncological efficacy of selective neck dissection (SND) in patients with T3-4 N0 laryngeal squamous carcinoma.A total 327 underwent 654 dissections; each side was individually evaluated.Three percent who had SND developed regional recurrence (RR) comparison 11.7 modified radical (MRND) (P=0.005). Only 3 (0.9%) RR outside field SND. The presence extracapsular extension (P=0.002) node-positive (pN+) group and microvascular invasion (P=0.007), together type (ND) (P=0.0003)...
The aim of this study was to evaluate the association between characteristic and outcomes in patients with lymph node metastasis a Brazilian cohort.This examined retrospective cohort adult diagnosed differentiated thyroid cancer metastases from 1998 2015 two referral centers. Number, location, size extranodal extension (ENE) metastatic nodes were assessed correlated response initial therapy.A greater number nodes, larger size, presence lateral neck disease ENE all associated lower...
To assess whether supracricoid laryngectomy with cricohiodoepiglottopexy could successfully reach the cure and preserve voice in glottic laryngeal cancer, we studied 27 patients T2/T3 squamous cell carcinoma of larynx treated our institution cricohiodoepiglottopexy.A retrospective analysis has been carried out between 1995 through 1997. We classified 11 as T2N0M0 16 T3N0M0. Nineteen had bilateral selective lateral neck dissection, 3 unilateral 5 undissected neck. Survival was analyzed under...
Abstract Background The ultrasonic scalpel is a recently introduced device in head and neck surgery. Total thyroidectomy the most common endocrine procedure performed by surgeons. Methods This was an open, phase IV, multicenter, randomized controlled trial (RCT) that compared use of with conventional technique patients who underwent total thyroidectomy. outcomes were surgical complication rate, operative time, drainage volume, postoperative pain, costs. Results In all, 261 included 11...
<i>Hypothesis:</i> The combination of chemotherapy and radiotherapy is a standard nonsurgical treatment for locally advanced laryngeal cancer. Nevertheless, there are no validated markers to predict the outcome therapies. impact previous tracheotomy not clear in patients submitted concomitant chemoradiotherapy. <i>Study Design:</i> A non-randomized prospective study. Prognostic factors such as stage, age, performance status, number cycles, dose, stage VIb disease,...
J Oral Pathol Med (2010) 40: 456–459 Background: Metastasis of salivary gland tumors has a negative impact on survival. Angiogenesis and its factors are potential markers for predicting metastasis in different malignant tumors, but this is not the case tumors. Methods: Salivary distinct biologic behavior were analyzed according to semiquantitative immunoexpression vascular endothelial growth factor (VEGF) thymidine phosphorylase (TP). Results: Vascular expression was predominantly weak...
Adenoid cystic carcinoma (AdCC) of the salivary glands shows heterogeneous behaviour, with metastasis as a key indicator poor prognosis. Metallothionein (MT) expression has been associated prognosis diverse neoplasms. We evaluated prognostic factors for AdCC and role played by MT, focusing on metastatic behaviour.We reviewed files Brazilian National Institute Cancer between 1997 2004, obtaining 49 cases. Fourteen tumours had metastasized during follow-up. Among these, we identified cases...