A5082206805- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Phytochemicals and Antioxidant Activities
- Genomics, phytochemicals, and oxidative stress
- Body Composition Measurement Techniques
- Diet and metabolism studies
- Antioxidant Activity and Oxidative Stress
- Child Nutrition and Water Access
- Clinical Nutrition and Gastroenterology
- NF-κB Signaling Pathways
- Frailty in Older Adults
- Natural product bioactivities and synthesis
- Colorectal Cancer Screening and Detection
- Exercise and Physiological Responses
- Coffee research and impacts
- Cancer survivorship and care
- High Altitude and Hypoxia
- Immune Response and Inflammation
- Head and Neck Cancer Studies
- Immune Cell Function and Interaction
- Consumer Attitudes and Food Labeling
- Childhood Cancer Survivors' Quality of Life
- Child Nutrition and Feeding Issues
- Vitamin C and Antioxidants Research
- Obesity and Health Practices
University of Oslo
2016-2025
Oslo University Hospital
2018-2025
UiT The Arctic University of Norway
2023-2024
Norwegian Directorate of Health
2022
Smerteklinikken
2021
Hudklinikken
2018
IFOM
2010
University of Minnesota
2010
European Institute of Oncology
2010
In this double-blind, randomised, controlled trial, we investigated the effects of vitamin C and E supplementation on endurance training adaptations in humans. Fifty-four young men women were randomly allocated to receive either 1000 mg 235 or a placebo daily for 11 weeks. During supplementation, participants completed an programme consisting three four sessions per week (primarily running), divided into high-intensity interval [4-6 × 4-6 min; >90% maximal heart rate (HRmax)] steady state...
SummaryBackground & aimsThe effect of lycopene-containing foods in prostate cancer development remains undetermined. We tested whether a lycopene-rich tomato intervention could reduce the levels specific antigen (PSA) patients.MethodsPrior to their curative treatment, 79 patients with were randomized nutritional either 1) products containing 30 mg lycopene per day; 2) plus selenium, omega-3 fatty acids, soy isoflavones, grape/pomegranate juice, and green/black tea (tomato-plus); or 3)...
The Global Leadership Initiative on Malnutrition (GLIM) has suggested a process for the diagnosis of malnutrition. consists applying an existing screening tool malnutrition screening, followed by diagnostics, and finally categorization severity (moderate or severe) according to specific GLIM criteria. However, it is not known how well agrees with other diagnostic tools used in current clinical practice. aim this study was validate against Patient Generated-Subjective Assessment (PG-SGA) when...
Background & aimsBioelectrical impedance analysis (BIA) is an accessible and cheap method to measure fat-free mass (FFM). However, BIA estimates are subject uncertainty in patient populations with altered body composition hydration. The aim of the current study was validate a whole-body segmental device against dual-energy X-ray absorptiometry (DXA) colorectal cancer (CRC) patients, investigate ability different empiric equations for predict DXA FFM (FFMDXA).MethodsForty-three non-metastatic...
Abstract Scope: Cytoprotective gene products, e.g. phase II – and antioxidant enzymes, are important in cellular redox homeostasis. A common feature of these genes is binding sites for transcription factor nuclear erythroid‐2‐related 2 (Nrf2), named electrophile response elements (EpREs) within their promoters. Methods results: To identify dietary bioactive compounds foods with Nrf2/EpRE inducing properties an intact organism, we utilized transgenic mice encoding luciferase under control...
Intake of fruits and berries may lower blood pressure (BP), most probably due to the high content polyphenols. In present study, we tested whether consumption two polyphenol-rich juices could BP. a randomised, double-blinded, placebo-controlled trial 12 weeks, 134 healthy individuals, aged 50-70 years, with normal range BP (130/85-139/89 mmHg, seventy-two subjects) or stage 1-2 hypertension (140/90-179/109 sixty-two subjects), were included. They consumed 500 ml/d one either (1) commercially...
The transcription factor NF-kappaB is a promising target for chemoprevention. Several dietary plants are efficient inhibitors of activation in vitro and could act synergistically on the signaling pathway. In this study, we tested whether plant extracts inhibit synergistic manner vitro. Second, investigated potency same inhibition vivo. A combined extract clove, oregano, thyme, walnuts, coffee inhibited lipopolysaccaride (LPS)-induced monocytic cell line, compared with sum effects from single...
Background Various altitude training regimes, systematically used to improve oxygen carrying capacity and sports performance, have been associated with increased oxidative stress inflammation. We investigated whether intake of common antioxidant-rich foods attenuates these processes. Methods In a randomized controlled trial, 31 elite endurance athletes (23 ± 5 years), ingested (n = 16), (> doubling their usual intake), or eucaloric control 15) during 3-week camp (2320 m). Fasting blood urine...
The Global Leadership Initiative on Malnutrition (GLIM) criteria is a step-wise process including screening tool of choice for risk assessment malnutrition before diagnosis and grading severity. agreement between GLIM the established method Patient Generated-Subjective Assessment (PG-SGA) uncertain. Also, several aspects remain to be clearly defined. In this study, we compared with PG-SGA, explored differences methods.This cross-sectional study was conducted at Nutrition Outpatient Clinic...
Colorectal cancer survivors are not only at risk for recurrent disease but also increased of comorbidities such as other cancers, cardiovascular disease, diabetes, hypertension and functional decline. In this trial, we aim investigating whether a diet in accordance with the Norwegian food-based dietary guidelines focusing dampening inflammation oxidative stress will improve long-term outcomes survival colorectal patients. This paper presents study protocol Dietary Guidelines Cancer Survival...
Disease-related malnutrition is a challenge among hospitalized patients. Despite guidelines and recommendations for prevention treatment, the condition continues to be prevalent. The MyFood system recently developed decision support prevent treat disease-related malnutrition.To investigate possible implementation of in clinical practice, aims study were (1) identify current routines, barriers, facilitators nutritional care; (2) potential barriers use MyFood; (3) key aspects an plan.A...
The Norwegian food-based dietary guidelines (FBDG) aim at reducing the risk of developing chronic diseases and promote overall health. We studied effect FBDG in colorectal cancer (CRC) patients. There is a need for time-efficient assessment tool measuring adherence to these patients treated dependent cancer, such as CRC patients.To evaluate new short food frequency questionnaire (NORDIET-FFQ), developed estimate among patients.Eighty-one from both study groups Dietary Guidelines Colorectal...
Tomatoes may protect against prostate cancer development, possibly through targeting signaling pathways such as nuclear factor-κB (NF-κB). We investigated whether tomato paste could modulate NF-κB activity and cancer-related gene expression in human derived cells (PC3) PC3 xenografts. PC3-cells were stably transduced with an NF-κB-luciferase construct, treated extracts or vehicle control. Nude mice bearing xenografts fed a Western-like diet without 10% for 6.5 wk. The significantly inhibited...
In the present study, we aimed at identifying mechanisms whereby vitamin A metabolite all-trans retinoic acid (RA) promotes formation of plasma cells upon stimulation B via innate immunity receptors TLR9 and RP105. Most often, differentiation involves sequential events class switch recombination somatic hypermutations characteristic germinal center reactions, followed by cell formation. By studying regulatory networks known to drive these revealed that RA enhances expression cell-generating...
High doses of isolated antioxidant supplements such as vitamin C and E have demonstrated the potential to blunt cellular adaptations training. It is, however, unknown whether intake high antioxidants from foods has similar effects. Hence, aim study was investigate antioxidant‐rich affects altitude training in elite athletes. In a randomized controlled trial, 31 national team endurance athletes (23 ± 5 years) ingested (n = 16) or eucaloric control 15) daily during 3‐week camp (2320 m)....
Compliance to guidelines for disease-related malnutrition is documented as poor. The practice of using paper-based dietary recording forms with manual calculation the patient's nutritional intake considered cumbersome, time-consuming and unfeasible among nurses does often not lead appropriate treatment. We developed digital decision support system MyFood deliver a solution these challenges. comprised an app patients website includes functions recording, evaluation compared requirements,...