A5100650035- Nanoplatforms for cancer theranostics
- Neuroblastoma Research and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Nanoparticle-Based Drug Delivery
- Renal cell carcinoma treatment
- Radiomics and Machine Learning in Medical Imaging
- Cultural Differences and Values
- Nanocluster Synthesis and Applications
- Culture, Economy, and Development Studies
- Antifungal resistance and susceptibility
- Neonatal Respiratory Health Research
- Fungal Infections and Studies
- Advanced X-ray and CT Imaging
- Advanced Image Processing Techniques
- Stroke Rehabilitation and Recovery
- Advancements in Battery Materials
- Medical Imaging Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
- Spatial Neglect and Hemispheric Dysfunction
- Venous Thromboembolism Diagnosis and Management
- Gastroesophageal reflux and treatments
- Ginseng Biological Effects and Applications
- Porphyrin Metabolism and Disorders
- Probiotics and Fermented Foods
- Ferroptosis and cancer prognosis
Nanjing Medical University
2021-2025
Tianjin University of Science and Technology
2017-2025
Qiqihar Medical University
2018-2024
Fujian University of Traditional Chinese Medicine
2018-2024
Weifang Medical University
2023-2024
Chinese PLA General Hospital
2022
Tianjin Medical University Cancer Institute and Hospital
2022
Harbin Electric Corporation (China)
2022
Tianjin Medical University
2011-2021
Hubei University of Medicine
2016
Probiotics isolated from the fermented grains of Chinese baijiu can prevent drunkenness, aid sobriety, protect against chronic alcoholic liver injury, and modulate intestinal flora imbalance short-chain fatty acids in affected mice.
Hereditary juvenile megaloblastic anemia due to vitamin B 12 (cobalamin) deficiency is caused by intestinal malabsorption of cobalamin. In Imerslund–Gräsbeck syndrome (IGS), cobalamin absorption completely abolished and not corrected the administration intrinsic factor (IF); if untreated, disease fatal. Biallelic mutations either in cubilin ( CUBN ) or amnionless AMN gene cause IGS. a series families clinically diagnosed with likely IGS, at least six displayed no evidence . A genome-wide...
The nano drug delivery system MnO 2 /CDDP@PDA-Cy5.5 was synthesized in this study to increase the efficacy of Cisplatin (CDDP) on thyroid cancer and alleviate damage normal tissue, with aim enhancing anti-cancer efficacy, increasing load, optimizing control release, alleviating systemic toxicity arising from off-target. On that basis, high low win-win can be obtained. In study, hollow manganese dioxide nanoparticles (MnO NPs) were prepared based template method. CDDP loaded into cavity then...
Stroke induces disorder of gut microbiota, however, whether this differs according to stroke severity and its role in the evolution outcome is currently unknown. Here we explored composition structure fecal microbiome based on 68 acute ischemic patients presenting with minor symptoms (admission National Institute Health Scale (NIHSS) ≤ 3) 67 non-minor NIHSS 4-34) using high-throughput Illumina sequencing 16S rRNA. There was no significant difference α-diversity indices, but principal...
Purpose: Acute ischemic stroke (AIS) has seriously threatened people's health worldwide and there is an urge need for early diagnosis effective treatment of AIS. This research intended to clarify the regulatory role circ_0008146/miR-342-5p/ACSL4 axis in Methods: High-throughput small RNA sequencing analysis was adapted identify differentially expressed miRNAs between AIS control group. The circ_0008146, miR-342-5p, ACSL4 levels were detected by qRT-PCR. Middle cerebral artery...
Vascular dementia (VaD) is the second most common in world. An increasing number of studies have demonstrated important role long non-coding RNAs (lncRNAs) VaD. Our previous investigation that Trimethylamine-N-oxide (TMAO) exacerbates cognitive impairment and neuropathological alterations VaD rats. Thus, we hypothesized TMAO could play an injury by regulating lncRNAs.
Abstract This paper describes the design and characterization of a limited number areas to be used as spatial monitoring reporting units ( MRU ) by CropWatch, global crop system http://www.cropwatch.com.cn/ hosted Chinese Academy Sciences. The s are modified adapted from an existing standard vegetation zoning map. They designed uniform vulnerability assessed three sets variables: environmental (such climate NDVI ), seasonality intra‐annual variations interannual variability) agronomy...
A worldwide decline in the quality of human semen is currently occurring. In mammals, sperm are produced from diploid stem-cell spermatogonia by spermatogenesis testes and become mature epididymis. Nevertheless, these biological processes can be affected Gram-negative bacterial infection mediated lipopolysaccharide (LPS), major endotoxin bacteria. It well known that LPS disturb affect maturation vivo. However, effect on ejaculated vitro remains unclear. Thus, this study aimed to assess...
Objective We investigated the potential of dual-energy computed tomography (DECT) radiomics in assessing cancer-associated fibroblasts clear cell renal carcinoma (ccRCC). Methods A retrospective analysis was conducted on 132 patients with ccRCC. The arterial and venous phase iodine-based material decomposition images (IMDIs), virtual non-contrast images, 70 keV, 100 150 keV monoenergetic mixed energy (MEIs) were obtained from DECT datasets. On Radcloud platform, feature extraction,...
The combination of magnetic resonance and fluorescence imaging in dual-modality not only resolves the limitations conventional single molecular techniques terms specificity, sensitivity, resolution but also expands possibilities diagnostics therapeutic monitoring. Herein, a novel pH-responsive resonance/near-infrared (MR/NIRF) nanoprobe (MnO
Nanodrug delivery system (NDDS) has been widely used in tumor diagnosis, chemotherapy, and image-guided surgery. In this work, hollow manganese dioxide nanoparticles (H-MnO2 NPs) were prepared by the template method, followed loading with Methotrexate (MTX), coating dopamine (PDA), coupling fluorescent dye Cy5.5. Finally, NDDC (MnO2/MTX@PDA-Cy5.5 NPs, MMPC NPs), capable of dual-mode imaging was successfully synthesized. NPs can realize high-efficiency MTX continuous release pH response...
Objectives. To investigate whether hUC-MSCs attenuated severe burn-induced ALI and the effects were based on TSG-6 secreted from hUC-MSCs. Method. A rat model was established evaluated as follows: cytokine expression measured by ELISA, both inflammatory cell infiltration lung injury assessed immunohistochemistry assay. Results. In vitro, levels in serum burn group significantly increased compared with those sham group. vivo, of tissues burn+hUC-MSC Both serum, proinflammatory cytokines...
The high-performance liquid chromatography (HPLC) fingerprint technique is an effective method to evaluate the quality, identify species, ensure consistency and stability of traditional Chinese medicine (TCM). In this study, determination was performed on Agilent ZORBAX SB-C18 (4.6 × 250 mm, 5 µm) column with methanol-water as mobile phase in gradient elution at flow rate 0.8 mL/min, temperature 30°C, detection wavelength set 260 nm. HPLC fingerprints 10 batches extract aerial parts from...
Intelligent medical imaging plays an irreplaceable role in improving the accuracy and efficiency of clinical diagnosis. Image segmentation is most important part study tumor features. This paper combines algorithms field image proposes a semi-automatic algorithm based on polar adaptive median filtering region growing to achieve accurate images, thus laying foundation for obtaining morphological features images.
Autism spectrum disorder (ASD), a highly hereditary and heterogeneous neurodevelopmental disorder, is influenced by genetic environmental factors. Tuberous sclerosis complex (TSC) common syndrome associated with ASD. Cytomegalovirus (CMV) infection an risk factor for The similarities in pathological mechanistic pathways of TSC CMV intrigued us to investigate whether interacted ASD's occurrence. We detected IgG seroprevalence 308 patients from our prospective cohort (September 2011 March...
Objective: This study aimed to analyze the efficacy of autologous peripheral blood stem cell transplantation for high-risk neuroblastoma in China. Methods: The data 90 patients treated with CCCG-NB 2015 regimen were reviewed. baseline clinicopathological characteristics and prognosis analyzed compared. In addition, prognoses tandem single groups Results: results survival analysis showed that based on this pretreatment significantly improved children group. 3-year event-free (EFS) overall...