- Heavy metals in environment
- Pregnancy and preeclampsia studies
- Medical Imaging Techniques and Applications
- Cancer-related molecular mechanisms research
- Bone health and osteoporosis research
- Bone fractures and treatments
- Wound Healing and Treatments
- Pleural and Pulmonary Diseases
- Automotive and Human Injury Biomechanics
- X-ray Spectroscopy and Fluorescence Analysis
- MicroRNA in disease regulation
- RNA modifications and cancer
- Nuclear Physics and Applications
- Environmental Impact and Sustainability
- Circular RNAs in diseases
- Preterm Birth and Chorioamnionitis
- Advanced oxidation water treatment
- Advanced Neuroimaging Techniques and Applications
- Silk-based biomaterials and applications
- Nerve Injury and Rehabilitation
- Tendon Structure and Treatment
- Bee Products Chemical Analysis
- Hormonal and reproductive studies
- Anesthesia and Sedative Agents
- Myofascial pain diagnosis and treatment
University of International Business and Economics
2024
Anhui Medical University
2023
Nanjing Medical University
2016-2023
Suzhou Municipal Hospital
2023
Fudan University
2023
Affiliated Hospital of Jiangsu University
2018-2021
Jiangsu University
2018-2021
Tongji University
2012-2020
State Key Laboratory of Pollution Control and Resource Reuse
2014-2020
Université Claude Bernard Lyon 1
2013-2017
Resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs), such as erlotinib and gefitinib, is a major clinical problem in the treatment of patients with non-small cell lung cancer (NSCLC). YM155 survivin small molecule inhibitor has been demonstrated induce apoptosis autophagy. EGFR-TKIs have known In this study, we showed that markedly enhanced sensitivity EGFR-TKI resistant NSCLC lines H1650 (EGFR exon 19 deletion PTEN loss) A549 wild type KRAS mutation)...
Preterm birth (PTB) is the main driver of newborn deaths. The identification pregnancies at risk PTB remains challenging, as incomplete understanding molecular mechanisms associated with PTB. Although several transcriptome studies have been done on placenta and plasma from women, a comprehensive description RNA profiles lacking.Candidate markers consistent trends in were identified by implementing differential expression analysis using placental tissue maternal RNA-seq datasets, then...
"Relationship between human rib mechanical properties and cortical bone density measured by high-resolution quantitative computed tomography." Computer Methods in Biomechanics Biomedical Engineering, 16(sup1), pp. 191–192Keywords:: ribmechanical propertiesthree-point bendingcortical (Ct BMD)HR-pQCT (high-resolution peripheral tomography) AcknowledgementsThe authors acknowledge Charlène Delimoge for technical contributions to this study Nicolas Vilayphiou input HR-pQCT data collection. Yumin...
BACKGROUND:Skin fibroblasts are primary mediators underlying wound healing and therapeutic targets in scar prevention treatment. CD26 is a molecular marker to distinguish fibroblast subpopulations plays an important role modulating the biological behaviors of dermal influencing skin repair. Therapeutic targeting specific subsets expected reduce formation more efficiently. MATERIAL AND METHODS:Skin burn excisional models were surgically established mice. The expression patterns during...
Elasticity of the child rib cortical bone is poorly known due to difficulties in obtaining specimens perform conventional tests. It was shown on femoral that elasticity strongly correlated with density for both children and adults through a unique relationship. Thus, it assumed relationships between adult bones could be expanded include children. This study estimated vivo using quantitative computed tomography (QCT). Twenty-eight (from 1 18 y.o.) were considered. Calibrated QCT images...
Recent studies in mouse models have demonstrated that the multi-cellular rosette structure of adrenal zona glomerulosa (ZG) is crucial for aldosterone production by ZG cells. However, human has remained unclear. The cortex undergoes remodeling during aging, and one surprising change occurrence aldosterone-producing cell clusters (APCCs). It intriguing to know whether APCCs form a like normal In this study, we investigated with without APCCs, as well APCCs. We found glomeruli are enclosed...
Objective To investigate whether S-ketamine affects the Surgical Pleth Index (SPI) during video-assisted thoracoscopic surgery. Methods Eighty-four patients undergoing lung lobectomy were enrolled. They randomly assigned to an group (group S) and equivalent normal saline N). SPI values recorded; pain score on a numerical rating scale (NRS), consumption of opioids, rescue analgesia, post-operative nausea vomiting (PONV) evaluated. Results The heart rate significantly lower 30 minutes after...
Differential diagnosis between malignant pleural effusion (MPE) and benign (BPE) remains a clinical challenge.The aim of the study is to assess efficacy serum fluid (PF) miRNA panels in distinguishing MPE from BPE.Fourteen candidate miRNAs which were shown aberrant expression lung cancer based on previous studies tested by quantitative real-time PCR (qRT-PCR) 20 patients BPE patients. Significantly aberrantly expressed further assessed qRT-PCR all enrolled this study. A receiver operating...
The load–deflection response of the human trunk has been studied using various methods. different shapes observed may be due to methodology and population. purpose this study is quantify explain in vivo mechanical paediatric adult trunks during respiratory physiotherapy. Eight children aged 5–15 months eight healthy volunteers 30–87 years participated study. force applied by physiotherapist displacement targets on his hands were recorded. Parameters also measured calculated compare against...
Abstract Electron energy-loss spectrometry and energy-filtered imaging allow the possibility of detecting, quantifying mapping boron. Boron spatial distribution in biological tissue is particular interest for boron neutron capture therapy (BNCT) cancer. We have studied limits quantification using electron spectroscopy imaging. To evaluate concentration three types specimens were used. First, a uniform layer well known thickness deposited onto 50 nm-thick carbon film was used to determine...