- Clinical practice guidelines implementation
- Health and Medical Studies
- Noise Effects and Management
- Health Systems, Economic Evaluations, Quality of Life
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Chronic Disease Management Strategies
- HIV/AIDS Research and Interventions
- Peripheral Artery Disease Management
- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Vehicle Noise and Vibration Control
- HIV, Drug Use, Sexual Risk
- Economic and Financial Impacts of Cancer
- Emergency and Acute Care Studies
- Vascular Procedures and Complications
- Breast Cancer Treatment Studies
- Childhood Cancer Survivors' Quality of Life
- Cerebrovascular and Carotid Artery Diseases
- Musculoskeletal pain and rehabilitation
- Cardiovascular Function and Risk Factors
- Global Cancer Incidence and Screening
- Healthcare Policy and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Lymphoblastic Leukemia research
Wissenschaftliches Institut der AOK
2019-2025
AOK
2022-2023
Universitätsklinikum Gießen und Marburg
2021
Charité - Universitätsmedizin Berlin
2021
West Cancer Center
2021
University of Duisburg-Essen
2021
University Hospital Carl Gustav Carus
2016-2018
Technische Universität Dresden
2012-2018
According to the National Cancer Plan in Germany, all cancer patients should receive high-quality care accordance with evidence-based treatment guidelines. Certification programs were established for this purpose but have not yet been comprehensively evaluated.
Background: The global rise of obesity and its association with cardiovascular risk factors (CVRF) have highlighted connection to chronic heart failure (CHF). Paradoxically, obese CHF patients often experience better outcomes, a phenomenon known as the ‘obesity paradox’. This study evaluated paradox’ within large cohort in Germany explored how varying degrees affect HF outcome. Methods: Anonymized health claims data from largest German insurer (AOK) for years 2014–2015 were utilized analyze...
Abstract Background Certified cancer centers aim to ensure high-quality care by establishing structural and procedural standards according evidence-based guidelines. Despite the high clinical health policy relevance, evidence from a nation-wide study for effectiveness of colorectal in certified vs. other hospitals Germany is still missing. Methods In retrospective cohort covering years 2009–2017, we analyzed patient data using demographic information, diagnoses, treatments nationwide...
The prevalence of chronic limb-threatening ischaemia (CLTI) is increasing and available data often derive from cohorts with various selection criteria. In the present study, we included CLTI patients studied sex-related differences in their risk profile, vascular procedures, long-term outcome.We analysed 199 953 unselected largest public health insurance Germany (AOK: Local healthcare funds), hospitalized between 2010 2017 for a main diagnosis CLTI. A baseline period 2 years before index...
Background To evaluate the association of age with long-term outcome after thrombectomy. Methods In a retrospective cohort study based on routine healthcare data from Germany between 2010 and 2018, we included 18 506 patients acute ischaemic stroke treated mechanical Association mortality, disability, level care at 1 year was assessed. Results The median 76 years, 36.3% were aged ≥80 years 55.8% women. Patients compared those <80 had higher mortality (55.4% vs 28.5%; adjusted HR 1.13; 95%...
Traffic noise can induce stress reactions that have effects on the cardiovascular system. The exposure-risk relationship between aircraft, road, and rail traffic myocardial infarction is currently unknown.19 632 patients from Rhine-Main region of Germany who were diagnosed with in years 2006-2010 compared 834 734 control subjects. assignment persons to groups was performed basis billing prescription data three statutory health insurance carriers. exposure all insurees 2005 determined their...
To examine the stroke risks associated with aircraft, road traffic, and railway noise exposure in a large case-control study.
Abstract Certified breast cancer centers offer specific quality standards in terms of their structure, diagnostic and treatment approaches with regards to surgery, drug-based therapy, radiotherapy, psychosocial support. Such aim improve outcomes patients. The question investigated here was whether patients primary have a longer overall survival if they are treated certified center compared outside these centers. We used patient-specific data (demographics, diagnoses, treatments) obtained...
Abstract Background Sepsis is associated with about 20% of deaths worldwide. It often presents non-specific initial symptoms, making its emergency treatment an interdisciplinary and cross-sectoral challenge. Three in four sepsis survivors suffers from new cognitive, psychological, or physical sequelae for which specific concepts are scarce. The AVENIR project aims to improve the understanding patient pathways, subjective care experiences needs along entire healthcare pathway before, after...
The prevalence of lower extremity artery disease (LEAD) is increasing worldwide and sex-related differences are a current matter debate.We analysed claims data on unselected patients with in-patient treatment for LEAD intermittent claudication (IC; Rutherford grade 1-3) from 01.01.2014 to 31.12.2015. Data files included diagnostic procedural information two years before index, five-year follow-up.Our analysis comprised 42,197 IC patients, thereof 28,520 (68%) male. Male were younger (median:...
Acute myocardial infarction (AMI) is the leading cause of death worldwide. Outcome has improved during last decades due to secondary prevention and widespread coronary interventions, but recent studies still show sex differences insufficient drug adherence. We aimed determine in treatment strategies outcomes between women men with ST-elevation (STEMI) Germany.From Federal Association Local Health Insurance Funds (Allgemeine Ortskrankenkasse), 175,187 patients were identified who hospitalized...
Background: Temporary mechanical circulatory support devices (tMCS) are increasingly being used in patients with infarct-associated cardiogenic shock (AMICS). Evidence on patient selection, complications and long-term outcomes is lacking. We aim to investigate differences clinical characteristics, between receiving no tMCS or either intra-aortic balloon pump (IABP), veno-arterial extracorporeal membrane oxygenation (V-A ECMO) Impella® for AMICS, a particular focus outcomes. Methods: Using...
Correction to: Endometrial Cancer – Long-Term Survival in Certified Centers and Non-Certified HospitalsGeburtshilfe Frauenheilkd 2024; 84(10): 979-988DOI: 10.1055/a-1869-2060
Zusammenfassung Im Projekt VersKiK sollen durch Verlinkung von Daten des Deutschen Kinderkrebsregisters mit Routinedaten gesetzlicher Krankenkassen die Art und Häufigkeit Spätfolgen medizinische Versorgung Langzeitüberlebenden nach Krebs im Kindes-oder Jugendalter untersucht werden. Das Deutsche Kinderkrebsregister definierte eine Grundgesamtheit ca. 50 000 Personen Krebserkrankung Kindes- oder der Diagnosejahre 1991–2021 (Überleben bis mindestens 1.1.2017). Die Identifizierung...
The population-based integrated health care system called "Gesundes Kinzigtal" (Integrierte Versorgung Gesundes Kinzigtal, IVGK) was initiated more than 10 years ago in the Kinzig River Valley region, which is located Black Forest German state of Baden-Württemberg. IVGK intended to optimize while maximizing cost-effectiveness. It consists programs for promoting and enabling cooperation among service providers, as well a shared-savings contract that has enabled resources be saved every year....
Depression and anxiety (DA) are common mental disorders in patients with chronic diseases, but the research regarding their prevalence heart transplantation (HTx) is still limited. We performed an analysis of prognostic relevance DA who underwent HTx between 2010 2018 Germany. Data were obtained from Allgemeine Ortskrankenkasse (AOK), which largest public health insurance provider. Overall, 694 identified. More than a third them diagnosed before undergoing (n = 260, 37.5%). Patients more...
Currently, there is a big need for data on emergency department (ED) utilization in Germany. One reason the ongoing reorganisation of care. Possible sources are routine that being collected based legal regulations. Different payers and compensation systems have their own requirements collection.Due to sectoral separation health care services, no dataset or holder provide information all ED treatments From an administrative point view, Germany considered ambulatory outpatient inpatient from...
It has been shown previously that a relevant proportion of childhood cancer survivors suffers from late effects, which are often directly related to the itself or its therapy, resulting in particular follow-up needs, additionally burdening healthcare systems. Being diagnosed with at vulnerable stage development, this group is comparatively higher risk relapse subsequent cancer. Although national and international guidelines based on treatment modalities have developed, their implementation...
Abstract Background and Aims Current knowledge about upper extremity artery disease (UEAD) is scarce. This study aimed to evaluate the prevalence, treatment patterns, short- long-term outcomes of patients suffering from UEAD. Methods Retrospective health claims data who were hospitalized with a primary diagnosis UEAD between 2010 2017 analysed. The obtained 11 legally independent statutory insurance funds ‘AOK-Die Gesundheitskasse’. Risk factors, comorbidities, pharmacotherapy,...
Quality assurance for acute in-hospital care in Germany is based on compulsory comparisons between institutions, so-called external quality (EQA). The effectiveness of EQA has not yet been adequately studied. purpose the QUASCH project, which supported by Innovation Fund Federal Joint Committee, to investigate association and health outcomes, specifically with respect stroke.The analyses were data from 379 825 patients insured AOK insurance fund who acutely admitted a hospital because stroke...