A5080213086- Biometric Identification and Security
- Functional Brain Connectivity Studies
- Advanced Fluorescence Microscopy Techniques
- Optical Coherence Tomography Applications
- Advanced Neuroimaging Techniques and Applications
- Face and Expression Recognition
- Photonic and Optical Devices
- Advanced MRI Techniques and Applications
- User Authentication and Security Systems
- Microfluidic and Capillary Electrophoresis Applications
- Plasmonic and Surface Plasmon Research
- Photoacoustic and Ultrasonic Imaging
- Advanced Biosensing Techniques and Applications
- Microfluidic and Bio-sensing Technologies
- Privacy-Preserving Technologies in Data
- Cryptography and Data Security
- Electrowetting and Microfluidic Technologies
- Biosensors and Analytical Detection
- Digital Media Forensic Detection
- Advanced Steganography and Watermarking Techniques
- Psychology of Moral and Emotional Judgment
- Optical Coatings and Gratings
- Near-Field Optical Microscopy
- Nanofabrication and Lithography Techniques
- Photoreceptor and optogenetics research
Yunnan Normal University
2022-2025
Second Affiliated Hospital of Zhejiang University
2023
East China Normal University
2014-2022
Columbia University
2017-2022
New York State Psychiatric Institute
2017-2022
University of Michigan
2019-2022
New York Psychoanalytic Society and Institute
2017-2022
Michigan United
2019-2021
Shandong Youth University of Political Science
2008-2020
Tsinghua University
2016-2017
Optofluidic lasers are currently of high interest for sensitive intracavity biochemical analysis. In comparison with conventional methods such as fluorescence and colorimetric detection, optofluidic provide a method amplifying small concentration differences in the gain medium, thus achieving sensitivity. Here, we report development an on-chip ELISA (enzyme-linked immunosorbent assay) laser platform that is able to complete assay short amount time sample/reagent volumes, large dynamic range,...
We develop a hybrid optofluidic microcavity by placing microsphere with diameter ranging from 1 to 4 μm in liquid-filled plano-plano Fabry–Perot (FP) cavities, which can provide an extremely low effective mode volume down 0.3–5.1 μm3 while maintaining high Q-factor up 1×104–5×104 and finesse of ∼2000. Compared the pure FP cavities that are known suffer lack confinement, diffraction, geometrical walk-off losses as well being highly susceptible mirror misalignment, our microsphere-integrated...
Little attention has been paid to the place attachment and homeland construction for refugees their descendants in China. This study investigates process by which of Young Overseas Chinese Relatives is shaped context resettlement sites. qualitative research employed ethnographic fieldwork, author collected local literature materials from February December 2019 through participatory observation, in-depth interviews, questionnaires. It believed that a new community, emotional experience...
Although the default mode network (DMN) is knowing to be abnormal in schizophrenia patients with auditory verbal hallucinations (AVHs), it still unclear whether AVHs occurred are associated certain information flow DMN. The present study collected resting-state functional magnetic resonance imaging data from 28 first-episode, drug-naïve AVHs, 20 without and 38 healthy controls. We used Granger Causality Analysis (GCA) examine effective connectivity of two hub regions (posterior cingulate...
Single cell manipulation technology has been widely applied in biological fields, such as injection/enucleation, physiological measurement, and imaging. Recently, a biochip platform with novel configuration of electrodes for 3D rotation successfully developed by generating rotating electric fields. However, the still two major shortcomings that need to be improved. The primary problem is there no on-chip module facilitate placement single into chamber, which causes very low efficiency...
Intergroup relationships can impact on a third party's willingness to punish violator, but few researchers have explored how intergroup affect third-party compensation tendencies. We recruited 163 participants observe dictator game, and then choose either the or compensate recipient, each of whom could be from participant's in-group out-group. Third parties often chose not dictators both victims out-group victims. When members transgressed against in-group, punished these just as they...
Persistent somatoform pain disorder (PSPD) is a mental un-associated with any somatic injury and can cause severe somatosensory emotional impairments in patients. However, so far, the neuro-pathophysiological mechanism of functional PSPD still unclear. The present study assesses difference regional spontaneous activity between healthy controls (HC) during resting state, order to elucidate neural mechanisms underlying PSPD. Resting-state Magnetic Resonance Imaging data were obtained from 13...
Leveraging microfluidics and nano-plasmonics, we present in this paper a new method employing micro-nano-device that is capable of monitoring the dynamic cell-substrate attachment process at single cell level real time without labeling. The essentially has gold thin film as substrate perforated with periodic, near-cm
We demonstrated the ultrasound modulated droplet lasers, in which laser intensity from whispering gallery mode (WGM) of oil droplets can be reversibly enhanced up to 20-fold when pressure is beyond a certain threshold. The lasing enhancement was investigated with various frequencies and pressures. Furthermore, modulation output achieved by controlling pressure, duty cycle, frequency bursts. Its potential application explored via study on human whole blood vessel phantom. A theoretical...
Advances in imaging and recording of neuron activities with a single cellular resolution have played significant role understanding neurological diseases signaling. Conventional methods relying on patch-clamps electrodes are regarded as invasive, whereas fluorescence-based tools useful but still suffer from low signal-to-noise ratio sensitivity. Here we developed an optical system by employing laser emissions to record ion influx neurons neuronal networks caused subtle Ca2+ transients vitro...
Emerging cell-based therapies such as stem cell therapy and immunotherapy have attracted broad attention in both biological research clinical practice. However, a long-standing technical gap of is the difficulty directly assessing treatment efficacy via tracking therapeutically administered cells. Therefore, imaging techniques to follow
The functional membrane proteins on tumor-cell-derived EVs contain a large amount of biomolecular information, and can serve as comprehensive marker to delineate the molecular nature cancer. However, due low secretion rates, it is difficult perform accurate quantification analysis with conventional EV technologies such Western blots. Here, we introduce multifunctional technology based an automated microfluidic chemiluminescent ELISA (Enzyme-Linked ImmunoSorbent Assay) platform. With this...
Abstract Introduction Previously in a three‐generation study of families at high risk for depression, we found that belief the importance religion/spirituality (R/S) was associated with thicker cortex bilateral parietal and occipital regions. In same sample using functional magnetic resonance imaging electroencephalograph (EEG), offspring familial had thinner cortices, increased default mode network connectivity, reduced EEG power. These group differences were significantly diminished who...
Emerging cell-based regenerative medicine and stem cell therapies have drawn wide attention in medical research clinical practice to treat tissue damage numerous incurable diseases. In vivo observation of the distribution, migration, development transplanted cells is important for both understanding mechanism evaluating treatment efficacy safety. However, tracking 3D migration trajectories individual therapeutic clinically relevant pathological environments remains technically challenging....
3D spinal structures segmentation is crucial to reduce the time-consumption issue and provide quantitative parameters for disease treatment surgical operation. However, most related studies of are based on 2D or single structure segmentation. Due high complexity structures, multiple with consistently reliable accuracy still a significant challenge. We developed validated relatively complete solution simultaneous semantic at voxel level named as S <sup...
Introduction Previous studies have shown disrupted effective connectivity in the large-scale brain networks of individuals with major depressive disorder (MDD). However, it is unclear whether these changes differ between first-episode drug-naive MDD (FEDN-MDD) and recurrent (R-MDD). Methods This study utilized resting-state fMRI data from 17 sites Chinese REST-meta-MDD project, consisting 839 patients 788 normal controls (NCs). All was preprocessed using a standardized protocol. Then, we...
Introduction: Attention deficit and hyperactivity disorder (ADHD) is a common inherited disease of the nervous system whose cause(s) pathogenesis remain unclear. Currently, diagnosis ADHD mainly based on clinical experience guidelines that have laid out some diagnostic standards. Our study aimed to apply learning-based classification method assist high-dimensional resting-state fMRI. Methods: selected ADHD-200 Peking dataset fMRI, which has an patient (n = 142) group typically developing...
Single cell manipulation technology has been widely applied in biological fields. Recently, a biochip platform with novel configuration of electrodes for 3-D rotation successfully developed. However, the still two major shortcomings manual place single and unstable rotation, which need to be addressed. To solve problems, this paper we propose new microfluidic chip capabilities trap stable both on one chip. The integrates parts: i) top capture part is based least flow resistance principle...
Fingerprint matching is one of the most important modules in Automatic Identification System (AFIS). This paper proposes a minutiae algorithm that uses minutiae-centered circular regions to help ensure stablity and robustness non-linear distortion. In our method, region constructed around each minutia, which can be regarded as secondary feature. Using regions, proposed find matched more rapidly via regional matching. Since minutia 's formed from only small area fingerprint, tolerant...