A5072681198- Adenosine and Purinergic Signaling
- Toxoplasma gondii Research Studies
- Animal Nutrition and Physiology
- Trypanosoma species research and implications
- Helminth infection and control
- Mycotoxins in Agriculture and Food
- Cholinesterase and Neurodegenerative Diseases
- Insect and Pesticide Research
- Nicotinic Acetylcholine Receptors Study
- Selenium in Biological Systems
- Heme Oxygenase-1 and Carbon Monoxide
- Meat and Animal Product Quality
- Calcium signaling and nucleotide metabolism
- Parasitic Infections and Diagnostics
- Reproductive Physiology in Livestock
- Synthesis and Biological Evaluation
- Parasites and Host Interactions
- Cytomegalovirus and herpesvirus research
- Curcumin's Biomedical Applications
- Research on Leishmaniasis Studies
- Herpesvirus Infections and Treatments
- Medicinal Plants and Neuroprotection
- Coccidia and coccidiosis research
- Rabbits: Nutrition, Reproduction, Health
- Sulfur Compounds in Biology
Universidade Federal de Santa Maria
2016-2025
Universidade Federal de Pelotas
2023-2025
Universidade do Estado de Santa Catarina
2013-2019
Faculdade Meridional
2018
Universidade Franciscana
2013-2017
Instituto Federal Catarinense
2017
Cancer and infectious diseases are among the leading causes of death in world. Despite diverse array treatments available, challenges posed by resistance, side effects, high costs, inaccessibility persist. In Solanaceae plant family, few studies with Vassobia breviflora species relating to biological activity known, but promising results have emerged. The phytochemicals present ethyl acetate fraction were obtained using ESI-MS-QTOF, antioxidants assays 1,1-diphenyl-2-picrylhydrazyl (DPPH),...
Hypertension is associated with platelet alterations that could contribute to the development of cardiovascular complications. Several studies have reported antiplatelet aggregation properties ginger (Zingiber officinale) and turmeric (Curcuma longa) limited scientific basis. Hence, this study assessed effect dietary supplementation these rhizomes on ectonucleotidase adenosine deaminase (ADA) activities in Nω-nitro-l-arginine methyl ester hydrochloride (l-NAME) induced hypertensive rats....
Vassobia breviflora belongs to the Solanaceae family, possessing biological activity against tumor cells and is a promising alternative for therapy. The aim of this investigation was determine phytochemical properties V. using ESI-ToF-MS. cytotoxic effects extract were examined in B16-F10 melanoma relationship if any purinergic signaling involved. antioxidant total phenols, (2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS) analyzed, as well...
Cutaneous melanoma (CM) is an aggressive and metastatic tumor, resulting in high mortality rates. Despite significant advances therapeutics, the available treatments still require improvements. Thus, purinergic signaling emerged as a potential pathway to cancer therapy due its involvement cell communication, proliferation, differentiation, apoptosis. In addition, safety acceptable clinical tolerability, carotenoids from microalgae have been investigated adjuvants anti-melanoma therapy. Then,...
Inflammation exerts a crucial pathogenic role in the development of hypertension. Hence, aim present study was to investigate effects ginger (<i>Zingiber officinale</i>) and turmeric (<i>Curcuma longa</i>) on enzyme activities purinergic cholinergic systems as well inflammatory cytokine levels N<i>ω</i>-nitro-L-arginine methyl ester hydrochloride-induced hypertensive rats. The rats were divided into seven groups (n = 10); 1–3 included normotensive control rats, (N<i>ω</i>-nitro-L-arginine...
Melanoma is the most aggressive type of skin cancer, with few therapeutic alternatives following metastasis development. In recent years, drug delivery-associated nanotechnology has shown promising targeted results diminished adverse effects compared to conventional treatments. This study aimed (1) examine plant-derived α-arbutin, a natural compound and (2) compare these findings bioactively developed liposomes containing α-arbutin utilizing B16-F10 murine melanoma cell line as model....
Abstract Sepsis is a generalized infection that involves alterations in inflammatory parameters, oxidant status, and purinergic signaling many tissues. Physical exercise has emerged as tool to prevent this disease because of its anti‐inflammatory antioxidant properties. Thus, study, we investigated the effects physical on preventing system components, oxidative stress, parameters lipopolysaccharide (LPS)‐induced sepsis rats. Male Wistar rats were divided into four groups: control, (EX), LPS,...