A5036052649- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Parasites and Host Interactions
- Antifungal resistance and susceptibility
- Cellular transport and secretion
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune cells in cancer
- Lysosomal Storage Disorders Research
- Insect Pest Control Strategies
- Lipid Membrane Structure and Behavior
- Toxin Mechanisms and Immunotoxins
- Extracellular vesicles in disease
- Phytochemical compounds biological activities
Universidade Federal de Minas Gerais
2018-2022
Intracellular parasites of the genus Leishmania are causative agents leishmaniasis. The disease is transmitted by bite a sand fly vector, which inoculates parasite into skin mammalian hosts, including humans. During chronic infection lives and replicates inside phagocytic cells, notably macrophages. An interesting, but overlooked finding, that other cell types even non-phagocytic cells have been found to be infected spp. Nevertheless, mechanisms invades such had not previously studied. Here,...
Cell signalling, cell secretion, and plasma membrane repair are processes that critically rely on intracellular vesicles, important components of the endocytic secretory pathways. More specifically, strategic distribution vesicles is for diverse cellular processes. The method presented here a simple, affordable, efficient tool to analyze such as lysosomes, endosomes, Golgi or granules under different experimental conditions. an accessible way density dispersion by combining...
ABSTRACT Intracellular parasites of the genus Leishmania are causative agents human leishmaniasis, a widespread emergent tropical disease. The parasite is transmitted by bite hematophagous sandfly vector that inoculates motile flagellated promastigote forms into dermis mammalian host. After inoculation, ultimately captured macrophages and multiply as round-shaped amastigote forms. Macrophages seem not to be first infected cells since were observed invading neutrophils whose...