- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Esophageal and GI Pathology
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Hernia repair and management
- Esophageal Cancer Research and Treatment
- Clinical practice guidelines implementation
- Intestinal and Peritoneal Adhesions
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Screening and Detection
- Surgical site infection prevention
- Anesthesia and Pain Management
- Renal cell carcinoma treatment
- Colorectal and Anal Carcinomas
- Hepatocellular Carcinoma Treatment and Prognosis
- Nutrition and Health in Aging
- Gastrointestinal disorders and treatments
- Enhanced Recovery After Surgery
- Stoma care and complications
- Health and Medical Research Impacts
- Surgical Sutures and Adhesives
Paracelsus Medical University
2024-2025
University Hospital Heidelberg
2015-2024
Heidelberg University
2015-2024
University of Freiburg
2007-2024
Nuremberg Hospital
2024
German Society of Surgery
2014-2024
Paracelsus Medizinische Privatuniversität
2024
Institut für Medizinische Biometrie, Informatik und Epidemiologie
2024
University Medical Center Freiburg
2006-2023
University Hospital Ulm
2023
The objective of this study was to identify potential risk factors for mortality and morbidity after distal pancreatectomy, with special focus on the formation pancreatic fistula.Distal pancreatectomy can be performed low acceptable rates. Pancreatic fistulas, occurring in 10% 20% cases, remain a problem that contributes significantly morbidity, length stay, overall costs.From November 1993 February 2006, perioperative postoperative data 302 consecutive patients were recorded. Univariate...
IDEAL is a framework for evaluations of surgical innovations, which follow distinct development pathway differing from the approach developed pharmacological interventions. Many and evaluation challenges are shared by other interventional therapies, requiring individual therapist skills customisation treatment to individual, partly through medical devices. This paper provides an overview recommendations, focuses on first two stages: idea development.
Objectives: To assess pancreatic fistula rate and secondary endpoints after pancreatogastrostomy (PG) versus pancreatojejunostomy (PJ) for reconstruction in pancreatoduodenectomy the setting of a multicenter randomized controlled trial. Background: PJ PG are established methods pancreatoduodenectomy. Recent prospective trials suggest superiority regarding perioperative complications. Methods: A trial comparing with was conducted involving 14 German high-volume academic centers surgery. The...
This dual-center, randomized, controlled, noninferiority trial aimed to prove that omission of drains does not increase reintervention rates after pancreatic surgery.There is considerable uncertainty regarding intra-abdominal drainage pancreatoduodenectomy.Patients undergoing head resection with pancreaticojejunal anastomosis were randomized versus no drainage. Primary endpoint was overall rate (relaparotomy or radiologic intervention). Secondary endpoints clinically relevant fistula (grade...
Open partial pancreatoduodenectomy (OPD) represents the current gold standard of surgical treatment a wide range diseases pancreatic head but is associated with morbidity in around 40% cases. Robotic (RPD) being used increasingly, yet, no randomised controlled trials (RCTs) RPD versus OPD have been published, leaving low level evidence to support this practice. This investigator-initiated, exploratory RCT two parallel study arms was conducted at high-volume centre line IDEAL recommendations...
In Brief Objective: patients undergoing midline incisions, the abdominal fascia can be closed with a continuous or interrupted suture using various materials. The aim of this study is to compare: (1) technique rapidly absorbable sutures and (2) techniques different slowly sutures, focusing on incidence incisional hernias within 1 year. Summary Background Data: A meta-analysis suggested that more effectively reduced sutures. Methods: Multicenter randomized surgical trial 3 parallel groups....
In Brief Objective: There are 2 main types of access for patients requiring major open, elective abdominal surgery: the midline or transverse approach. The aim this study is to compare both approaches by focusing on postoperative pain, complications, and frequency incisional hernias. Summary Background Data: A recent Cochrane review suggested that incisions may be less painful but hernia rates do not differ. Methods: Randomized, patient- observer-blinded, monocentric, equivalence clinical...