A5007162863- Acute Lymphoblastic Leukemia research
- Folate and B Vitamins Research
- Childhood Cancer Survivors' Quality of Life
- Dementia and Cognitive Impairment Research
- Carcinogens and Genotoxicity Assessment
- Cancer Risks and Factors
- Birth, Development, and Health
- Stroke Rehabilitation and Recovery
- Prenatal Screening and Diagnostics
- Physical Activity and Health
- Health and Well-being Studies
- Health disparities and outcomes
- Health and Wellbeing Research
- Coffee research and impacts
- Pregnancy and preeclampsia studies
- Frailty in Older Adults
- Nutrition and Health in Aging
- Housing, Finance, and Neoliberalism
- Air Quality and Health Impacts
- Radiation Dose and Imaging
- DNA Repair Mechanisms
- Cerebrovascular and genetic disorders
- Environmental Justice and Health Disparities
- Congenital Heart Disease Studies
- Telomeres, Telomerase, and Senescence
The University of Western Australia
2009-2024
The Kids Research Institute Australia
2010-2021
UNSW Sydney
2012
Children's Cancer Institute Australia
2012
Royal Perth Hospital
2012
Edith Cowan University
2012
Princess Margaret Hospital for Children
2012
Speech Pathology Australia
2010
Curtin University
2010
Government of Western Australia Department of Health
2010
Many observational studies have shown that physical activity reduces the risk of cognitive decline; however, evidence from randomized trials is lacking.To determine whether rate decline among older adults at risk.Randomized controlled trial a 24-week intervention conducted between 2004 and 2007 in metropolitan Perth, Western Australia. Assessors function were blinded to group membership.We recruited volunteers who reported memory problems but did not meet criteria for dementia. Three hundred...
Abstract A common T→C polymorphism of the KIBRA gene has been recently associated with worse performance on tests episodic memory. This should aimed to determine whether older adults CC genotype (1) have memory than T‐allele carriers and, (2) are more likely express phenotype amnestic mild cognitive impairment (MCI). Our Cross‐sectional investigation 312 aged 50–89 years free dementia included genotyping rs17070145 and assessment Establish a Registry for Alzheimer's Disease (CERAD)....
Positive associations have been reported between the measures of accelerated fetal growth and risk childhood acute lymphoblastic leukemia (ALL). We investigated this association by pooling individual-level data from 12 case-control studies participating in Childhood Leukemia International Consortium. Two growth-weight-for-gestational-age proportion optimal birth weight (POBW)-were analysed. Study-specific odds ratios (ORs) 95% confidence intervals (CIs) were estimated using multivariable...
Abstract Background: Interest in a possible protective effect of maternal vitamin use before or during pregnancy against childhood brain tumors (CBT) and other cancers has grown over the past decade. Our Australian study CBTs, conducted between 2005 2011, investigated whether folic acid supplements was protective. Methods: Case children were identified through 10 pediatric oncology centers controls recruited by national random digit dialing. Mothers 327 cases 867 control provided information...
ABSTRACT Background: Previous research has found an association between post-stroke depressive symptoms and premorbid personality. This study sought to investigate further the relationship personality a number of common behavioral psychological in three-month follow-up study. Methods: prospective was conducted May 2003 January 2005 Perth metropolitan teaching hospital. The pre-stroke stroke survivors assessed by interviewing close family member (informant) within four weeks index using NEO...
There has been increasing interest in the influence of diet on cognition elderly. This study examined cross-sectional association between dietary patterns and a sample 249 people aged 65–90 years with mild cognitive impairment (MCI). Two patterns; whole processed food; were identified using factor analysis from 107-item; self-completed Food Frequency Questionnaire. Logistic regression analyses showed that participants highest tertile food pattern score more likely to have poorer functioning;...
Childhood brain tumors (CBT) are the leading cause of cancer death in children, yet their etiology remains largely unknown. Tobacco smoke contains 61 known carcinogens and increases risk several adult cancers. This study investigated associations between parental smoking CBT a population-based case-control conducted 2005 2010. Cases were identified through all ten Australian pediatric oncology centers, controls via nationwide random-digit dialing, frequency matched to cases on age, sex state...
Parental occupational exposures have been associated with childhood brain tumours (CBT), but results are inconsistent. Few studies studied CBT risk and parental solvent exposure, suggesting a possible association. We examined the association between exposure to solvents in case–control study. Parents of 306 cases 950 controls completed detailed histories. Odds ratios (ORs) 95% confidence intervals (CIs) were estimated for both maternal paternal benzene, other aromatics, aliphatics...
To examine whether children conceived using assisted reproductive technology (ART) have a higher risk of intellectual disability (ID) compared with non-ART-conceived and describe known causes ID in these groups.We linked ART data from population-based registers Western Australia. Our cohort included live births 1994 to 2002 (n = 210 627) at least 8 years follow-up. The prevalence was between ART- children, estimated Poisson regression robust SEs. We also stratified by plurality gestation...
Childhood brain tumors (CBT) are the second most common childhood cancers, yet their etiology is largely unknown. We investigated whether maternal gestational intake of folate and vitamins B6 B12 was associated with CBT risk in a nationwide case-control study conducted 2005–2010. Case children 0–14 years were recruited from all 10 Australian pediatric oncology centers. Control by national random digit dialing, frequency matched to cases on age, sex, state residence. Dietary ascertained using...
Acute lymphoblastic leukemia (ALL) and childhood brain tumors (CBT) are 2 of the most common forms cancer, but little is known their etiology. In nationwide case-control studies we investigated whether breastfeeding, age food introduction, or early diet associated with risk these cancers. Cases aged 0-14 years were identified from Australian pediatric oncology units between 2003 2007 2005 2010 population-based controls through random-digit dialing. Mothers completed questionnaires giving...
Background Childhood brain tumors (CBT) are the leading cause of cancer death in children, yet their causes largely known. This study investigated association between maternal and birth characteristics risk CBT. Procedures Cases families were recruited from all 10 Australian pediatric oncology centers 2005 2010. Control via random-digit dialing, frequency matched to cases on basis child's age, sex, State residence. Maternal children ascertained by questionnaires. Odds ratios (ORs) 95%...
Impaired awareness of cognitive deficits is a common symptom dementia, but its prognostic importance in people with impairment-no dementia (CIND) uncertain. In this study, we examined whether community volunteers CIND and reduced had worse performance decline over 18 months than participants intact or healthy controls. We recruited 92 91 controls their respective informants. used discrepancy scores (informant minus participant) on the Anosognosia Questionnaire for Dementia Dysexecutive to...
Several studies suggest that maternal folic acid supplementation before or during pregnancy protects against childhood acute lymphoblastic leukemia (ALL). We investigated associations between ALL risk and folate pathway gene polymorphisms, their modification by supplements, in a population-based case-control study (2003-2007).
Reduced awareness of cognitive deficits in mild impairment (MCI) is associated with poorer outcomes although little known about the anatomical correlates this. We examined association insight and grey matter volume using a voxe