A5101910553- Metal complexes synthesis and properties
- Synthesis and Characterization of Heterocyclic Compounds
- Magnetism in coordination complexes
- Medicinal Plants and Neuroprotection
- Lanthanide and Transition Metal Complexes
- Diet, Metabolism, and Disease
- Phytochemicals and Medicinal Plants
- Biochemical Analysis and Sensing Techniques
- Organometallic Compounds Synthesis and Characterization
- Synthesis and biological activity
- Inorganic and Organometallic Chemistry
- Chemotherapy-induced cardiotoxicity and mitigation
- Metal-Catalyzed Oxygenation Mechanisms
- Pharmacological Effects of Natural Compounds
- Liver Disease Diagnosis and Treatment
- Probiotics and Fermented Foods
- Cancer Treatment and Pharmacology
- Microbial Metabolites in Food Biotechnology
- Antioxidant Activity and Oxidative Stress
- Pomegranate: compositions and health benefits
- Phytochemistry and Biological Activities
- Diet and metabolism studies
- Traditional Chinese Medicine Analysis
- Pain Mechanisms and Treatments
- Ethnobotanical and Medicinal Plants Studies
Swami Vivekanand College of Pharmacy
2022-2024
National Medical Products Administration
2019
University of Delhi
2013
Siddhartha Medical College
2011
Torrent Pharma (India)
2008
Maharaja Sayajirao University of Baroda
2006
University of Padua
1988
Abstract Acute subcutaneous administration of Angiotensin II (Ang II) causes a rise in blood pressure diabetic Wistar rats. Diabetes was induced using streptozotocin (70 mg/kg, i.v.). Chronic pomegranate juice (PJ) extract (100 mg/kg and 300 mg/kg; p.o. for 4 weeks) obtained from Punica granatum (punicaceae) fruits reduced the mean arterial vascular reactivity changes to various catecholamines also reversed biochemical by diabetes Ang II. PJ treatment caused significant decrease levels...
Abstract The study aimed to evaluate the protective role of myricetin obtained from Vitis vinifera (Vitaceae) on heart rate, electrocardiographic (ECG) patterns, vascular reactivity catecholamines, cardiac marker enzymes, antioxidant enzymes together with morphological and histopathological changes in isoproterenol (ISO) induced myocardial infarction (MI) male Wistar rats. Rats treated (85 mg/kg, administered subcutaneously twice at an interval 24 h) showed a significant increase rate ST...
Fructose feeding induces a rise in blood pressure normal rats and is associated with insulin resistance, hyperinsulinemia, hypertriglyceridemia. We have examined the effect of myricetin (100 300 mg/kg, p.o. for 6 weeks) isolated from Vitis vinifera Linn. (Vitaceae) on systolic (SBP), vascular reactivity, serum glucose, triglycerides, cholesterol, fructose-induced hypertension. Myricetin reduced reactivity changes to catecholamines reversed metabolic alterations induced by fructose. The...
To determine the protective role of Punica granatum L. (Punicaceae) seed juice extract and its butanolic fraction on heart rate, electrocardiographic patterns, vascular reactivity to catecholamines, cardiac marker enzymes, antioxidant enzymes together with morphologic histopathological changes in isoproterenol-induced myocardial infarction male Wistar rats.The effects (100 mg/kg, p.o. 300 p.o.) mg/kg., parameters were studied. Isoproterenol hydrochloride was used induce rats. At end...
Chronic administration of myricetin (100 and 300 mg kg−1, p.o., for 4 weeks) isolated from Vitis vinifera (Vitaceae) ameliorated hypertension oxidative stress induced by deoxycorticosterone acetate (DOCA)-salt in rats. Myricetin treatment reduced systolic blood pressure, vascular reactivity changes reversed the DOCA-induced increase heart rate. Urinary sodium excretion was significantly decreased animals treated with compared to DOCA group when measured flame photometer. The cumulative...
Probiotics are living microorganisms when administered in adequate amounts confer health benefits to the host. In present study, a soil isolate was identified as Bacillus subtilis based on 16S rRNA sequencing. probiotic functional characterization (in vitro), B. SKB/2074 produced 10 different enzymes, stable under simulated gastric conditions (pH 2.5/1-3 hr), bile salt (0.05-0.3% w/v), and temperature (40-90 °C) conditions. cells were non-hemolytic, found susceptible 30 antibiotics, showed...
A high throughput liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS-MS) method is developed for the simultaneous estimation of clopidogrel (SR25990C) and its carboxylic acid metabolite (SR26334) in human plasma using glimepiride as internal standard. The extraction SR25990C, metabolite, IS from (0.3 mL) involves treatment with phosphoric followed by solid-phase (SPE). Sample preparation this yields clean extracts quantitative consistent mean recoveries 98.05%,...
We investigated the antihypertensive effect of a methanol extract (ME) fenugreek seeds and its fraction (MF) in deoxycorticosterone acetate (DOCA)-salt-induced fructose-induced hypertensive rats. In DOCA model, (15 mg/kg, twice week; s.c.) was administered uni-nephrectomized animals for 4 weeks. Methanol (30 mg kg−1 day−1; p.o.) were evaluated their effect. fructose drinking water replaced with 10% solution 6 weeks to induce hypertension. ME (100 assessed model. After completion treatment...
A previous study from our laboratory has shown the facilitatory effect of Ceratonia siliqua L. (Fabaceae) on dopaminergic function. This investigates involvement monoamines in antidepressant activity total polyphenol content extract (CS) mice using a tail suspension test (TST) and forced swim (FST). The immobility time TST FST were significantly reduced by CS (25 50 mg kg−1, i.p.). considerably attenuated duration induced prazosin (62.5 µg i.p., an α-adrenoceptor antagonist) eticlopride (0.1...