A5101639627- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Sulfur Compounds in Biology
- Digital Transformation in Industry
- Photodynamic Therapy Research Studies
- Robotic Mechanisms and Dynamics
- Mechanical Engineering and Vibrations Research
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Advanced Image Fusion Techniques
- Tunneling and Rock Mechanics
- Molecular Sensors and Ion Detection
- Nanocluster Synthesis and Applications
- Drilling and Well Engineering
- Remote-Sensing Image Classification
- Advanced Image and Video Retrieval Techniques
- Soil Mechanics and Vehicle Dynamics
- RNA Interference and Gene Delivery
- Cancer, Hypoxia, and Metabolism
- Nanoparticle-Based Drug Delivery
Tianjin University
2023-2024
King's College London
2024
China University of Petroleum, Beijing
2024
Xidian University
2022
Shenyang Agricultural University
2021
Graph convolution networks (GCNs) have been applied in a variety of fields due to their powerful ability processing graph-like data. However, the massive number hyperspectral pixels makes it challenging define general graph structures on images (HSIs). On other hand, convolutional neural (CNNs) take regular image regions with fixed square size, and demonstrated impressive accuracy while being efficient computation. Inspired by classification framework CNNs, we develop GCN-based model that...
Hypoxia, which can promote tumor invasiveness and metastasis, is a major obstacle to various cancer therapies. At the same time, hypoxic microenvironment provides great target for achieving precise treatment. Here, we report nanoprodrug consisting of hypoxia-responsive doxorubicin prodrug pH-responsive photosensitizer-containing amphiphilic polymer. When accumulates in cells, acidic environment promotes disintegration nanoprodrug, beneficial improving generation efficiency singlet oxygen...
Photodynamic therapy (PDT) has attracted much attention in recent years due to its high selectivity; however, limited by the heterogeneity of a tumor oxygen environment, hypoxic region will be significantly resistant PDT. Herein, we report an level-responsive transformable therapeutic nanomedicine consisting hypoxia-responsive molecule (Cy-NO2), radical generator (ADVN), and pH-responsive polymer. In normoxic region, Cy-NO2 plays role photosensitizer under 808 nm laser irradiation realize...
Reactive oxygen species (ROS)-activated prodrugs offer high tumor selectivity due to an abnormal ROS level in cells. However, effective prodrug activation is still limited by inadequate endogenous ROS. Here, we report a ROS-activated nanoparticle consisting of iron-chelating polyprodrug. Due its nanostructure, the can achieve accumulation via passive targeting effect. Activated cancer cells, thioacetal linkers nanoparticles will be broken release cinnamaldehyde and chlorambucil. The former...
As one of the most promising technologies in industry, Digital Twin (DT) facilitates real-time monitoring and predictive analysis for real-world systems by precisely reconstructing virtual replicas physical entities. However, this reconstruction faces unprecedented challenges due to everincreasing communication overhead, especially digital robot arm reconstruction. To end, we propose a novel goal-oriented semantic (GSC) framework extract GSC information task DT, with aim minimising load...
Abstract Planar four-bar linkage is widely used in mechanical engineering. The degree of freedom the one, and different organizations lengths four bars could distinguish it several types. one crank-rocker mechanism. parameters decided by are wiping angle, transmission quick-return ratio, which were analyzed this report. Then three-dimensional model physical built. In addition, kinematic characteristics prototype deduced simulation, some experimental works researched dynamic characteristics....