A5102903187- Neuroscience and Neuropharmacology Research
- Visual perception and processing mechanisms
- Neural dynamics and brain function
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Retinal Development and Disorders
- Photoreceptor and optogenetics research
- Advanced materials and composites
- Vestibular and auditory disorders
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- High Entropy Alloys Studies
- Neurobiology and Insect Physiology Research
- Ophthalmology and Eye Disorders
- Organic Electronics and Photovoltaics
- Cancer-related molecular mechanisms research
- Metal and Thin Film Mechanics
- Intermetallics and Advanced Alloy Properties
- Aluminum Alloys Composites Properties
- Retinopathy of Prematurity Studies
- Crystal structures of chemical compounds
- High-Temperature Coating Behaviors
- Organic Light-Emitting Diodes Research
- Metal complexes synthesis and properties
- Magnesium Alloys: Properties and Applications
Tianjin Medical University
2016-2025
Tianjin Medical University Eye Hospital
2015-2025
Nankai University
2021-2025
Shandong University of Traditional Chinese Medicine
2024
Qinghai Provincial Peoples Hospital
2023-2024
Ningbo No. 2 Hospital
2023
Institute of Process Engineering
2023
Sun Yat-sen Memorial Hospital
2021
Sun Yat-sen University
2021
Northwestern University
2017-2018
Chronic kidney disease (CKD) in patients is strongly associated with cardiovascular morbidity and mortality, prevalent abnormal lipid metabolism. The AIM-HIGH trial examined the benefits of adding extended-release niacin (ERN) to simvastatin established coronary heart disease. Here we conducted a post hoc analysis examining whether participants derived or renal when stratified by function. Of 3414 participants, 505 had stage 3 CKD at baseline. Among subset, demographics (CVD) risk factors...
Detecting visual features in the environment is crucial for animals' survival. The superior colliculus (SC) implicated motion detection and processing, whereas how SC integrates inputs from two eyes remains unclear. Using vivo electrophysiology, we show that mouse contains many binocular neurons display robust ocular dominance (OD) plasticity a critical period during early development, which similar to, but not dependent on, primary cortex. NR2A- NR2B-containing N-methyl-D-aspartate (NMDA)...
Detection of salient objects in the visual scene is a vital aspect an animal’s interactions with its environment. Here, we show that neurons mouse superior colliculus (SC) encode saliency by detecting motion contrast between stimulus center and surround. Excitatory most superficial lamina SC are contextually modulated, monotonically increasing their response from suppression same-direction surround to maximal potentiation oppositely-moving The degree this declines depth SC. Inhibitory...
Amblyopia develops during a critical period in early visual development and is characterized by reduced sensory functions structural reorganization of the brain. However, little known about oculomotor amblyopes despite special role eye movements perception, task execution fixation. Therefore, we studied relationship deficits anisometropic amblyopia fixational saccadic movements.We recruited twenty-eight age-matched control subjects. Using high-speed eye-tracker, eye-movements both eyes were...
Background Idiopathic pulmonary fibrosis (IPF) has attracted considerable attention worldwide and is challenging to diagnose. Cuproptosis a new form of cell death that seems be associated with various diseases. However, whether cuproptosis-related genes (CRGs) play role in regulating IPF disease unknown. This study aims analyze the effect CRGs on progression identify possible biomarkers. Methods Based GSE38958 dataset, we systematically evaluated differentially expressed immune...
Amblyopia is a common eye disease that seriously affects children's health. The Chinese Association for Pediatric Ophthalmology and Strabismus has carried out lot of work the prevention treatment amblyopia, but there are still many problems need to be paid attention solved in amblyopia screening clinical diagnosis treatment. In this article, we discuss three aspects treatment, including timing according visual developmental patterns, standardized overdiagnosis commercialization,...
The visual thalamus serves as a critical hub for feature preprocessing in processing pathways. Emerging evidence demonstrates that experience-dependent plasticity can be revealed by monocular deprivation (MD) the dorsolateral geniculate nucleus (dLGN) of thalamus. However, whether and how this thalamic induces changes multiple receptive field properties potential mechanisms remain unclear. Using vivo electrophysiology, here we show binocular neurons dLGN 4-day MD mice starting at P28 undergo...
In primary visual cortex (V1), critical period for ocular dominance (OD) plasticity is a well-defined developmental stage to shape neuronal circuits based on experience. Recent studies showed that V1-like OD existed in mouse dorsal lateral geniculate nucleus (dLGN). It still unclear what the exact time window and how neural contribute dLGN. Using vivo electrophysiology, we defined dLGN from eye opening puberty. There also an innate process of formation contralateral equal bias binocular...
The cost of managing a chronic disease like glaucoma is quite large. A convenient and economical monitoring tool self-reported measures Quality Life (QoL) could have the potential to significantly reduce health economic burden this disease. However, evidence about whether QoL can effectively reflect both subjective objective clinical outcomes visual functions in patients lacking. In paper, we examined relationships between patients. This cross-sectional study enrolled 107 with broad range...
Abstract MoSi 2 functionally graded coating on Mo substrate is prepared by liquid-phase siliconizing technology. The SEM, GDS and XRD analysis shows that the silicon content in gradient layer appears three changing regularities. Along to surface of coating, phase composition changes as follows: → transition (main phase) + 3 Si 5 intermediate Si. According Si-Mo diffusion couple Arrhenius equation, activation energy ( Q ) was obtained 430 kJ·mol −1 , dependence D temperature can be described...
Oxidative stress exists in uremic milieu, particularly maintenance hemodialysis (MHD) patients, and accounts for certain long-term complications. Yet little is known about whether supplementation of ascorbic acid (vitamin C, or vitC) via extracorporeal circuit has substantial effects on minifying oxidative impairment.The entire experiment consisted three sections: 1) Practicing ascorbate dialysate among 8 MHD patients a single dialysis session, compared with conventional session another one...
To investigate the association between SERPING1 rs2511989 (G>A) polymorphism and age-related macular degeneration (AMD).A number of electronic databases (up to July 15, 2014) were searched independently by two investigators. A Meta-analysis was performed on AMD. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) estimated.Eight studies 16 cohorts consisting 9163 cases 6813 controls included in this Meta-analysis. There no significant AMD under all genetic models overall estimates...
Neurons in the visual system display varying degrees of selectivity for stimulus features such as orientation and direction. Such feature is generated processed by intricate circuit synaptic mechanisms. A key factor this process input-output transformation from membrane potential (Vm) to spikes individual neurons. Here, we use vivo whole-cell recording study Vm-to-spike superficial, visual, neurons mouse superior colliculus (SC). As expected spike threshold effect, direction increase Vm...