A5100338008- Oceanographic and Atmospheric Processes
- Marine and coastal ecosystems
- Climate variability and models
- Geology and Paleoclimatology Research
- Crystallization and Solubility Studies
- Soil and Water Nutrient Dynamics
- X-ray Diffraction in Crystallography
- Microbial Natural Products and Biosynthesis
- Geological and Geophysical Studies
- Tropical and Extratropical Cyclones Research
- Fish Ecology and Management Studies
- Ocean Waves and Remote Sensing
- Methane Hydrates and Related Phenomena
- Metal and Thin Film Mechanics
- Geological formations and processes
- Alkaloids: synthesis and pharmacology
- Advanced Battery Materials and Technologies
- Arctic and Antarctic ice dynamics
- Fungal Biology and Applications
- Atmospheric and Environmental Gas Dynamics
- Coastal and Marine Dynamics
- Astronomy and Astrophysical Research
- Selenium in Biological Systems
- High-pressure geophysics and materials
- Water Quality and Pollution Assessment
Henan University of Science and Technology
2023-2025
Institute of Oceanology
2015-2024
Qingdao National Laboratory for Marine Science and Technology
2016-2024
University of Chinese Academy of Sciences
2014-2024
Laoshan Laboratory
2024
Chinese Academy of Sciences
2015-2024
Lanzhou University
2024
Tianjin University of Science and Technology
2024
China International Science and Technology Cooperation
2024
Beijing Technology and Business University
2024
The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST, also called the Guo Shou Jing Telescope) is a special reflecting Schmidt telescope. LAMOST's design allows both large aperture (effective of 3.6 m–4.9 m) and wide field view (FOV) (5°). It has an innovative active configuration which continuously changes mirror's surface that adjusts during observation process combines thin deformable mirror optics with segmented optics. Its primary (6.67 m × 6.05 (5.74m 4.40m) are...
Importance The etiology of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease, is unknown. However, neuroinflammation and complement activation may play role in disease progression. Objective To determine the effects zilucoplan, an inhibitor C5, individuals with ALS. Design, Setting, Participants Zilucoplan was tested as regimen A HEALEY ALS Platform Trial, phase 2 to 3 multicenter, randomized, double-blind, placebo-controlled perpetual platform clinical trial sharing...
A new 3H-oxepine-containing alkaloid, varioxepine (1), characterized by a structurally unprecedented condensed 3,6,8-trioxabicyclo[3.2.1]octane motif, was isolated from the marine algal-derived endophytic fungus Paecilomyces variotii. Due to low proton/carbon ratio, unambiguous assignment of planar structure and relative configuration precluded NMR experiments solved single crystal X-ray analysis. The absolute established DFT conformational analysis TDDFT-ECD calculations. Compound 1...
This study investigated the variations of dissolved N 2 O and emissions over diurnal seasonal temporal scales in 2009, as well time series riverine export to estuary emission atmosphere response increasing anthropogenic nitrogen loads Changjiang River. For study, concentrations ranged from 0.26 0.34 0.44 0.52 μ g N–N L −1 August October respectively. The was supersaturated with a mean value 197%. Studies on emissions, also taken October, 2.67 11.6 6.72 15.2 m −2 h , (June through December...
Chermesins A–D (1–4), four new spiromeroterpenoids containing a drimane-type sesquiterpene skeleton, were isolated and identified from the culture extract of Penicillium chermesinum EN-480, an endophytic fungus obtained inner tissue marine red alga Pterocladiella tenuis. The structures these elucidated based on detailed spectroscopic analyses, their absolute configurations confirmed by single-crystal X-ray diffraction experiments ECD data. This is first report crystal that contain skeleton...
Hypoxia in tumor microenvironment (TME) represents an obstacle to the efficacy of immunotherapy for pancreatic ductal adenocarcinoma (PDAC) through several aspects such as increasing expression immune checkpoints or promoting fibrosis. Reversing hypoxic TME is a potential strategy improve validity checkpoint blockade (ICB).Here, we synthesized polydopamine-nanoparticle-stabilized oxygen microcapsules with excellent stabilization, bioavailability, and biocompatibility direct delivery into...
The aim of this study was to investigate the role selenomethionine (SeMet) in alleviating AFB1 induced intestinal injury by inhibiting oxidative stress. Forty 35-day-old rabbits were divided randomly into 4 groups (control group, 0.2 mg/kg Se + 0.4 group). From first day experiment, two treatment fed SeMet or daily for 21 days. On 17th day, all model group and given intragastric 5 ADG, ADFI FCR examined. Rabbit jejunum tissue collected hematoxylin- eosin staining (HE), PCNA detection,...
Abstract The surface circulation of the tropical Pacific Ocean is characterized by alternating zonal currents, such as North Equatorial Current (NEC), Countercurrent (NECC), South (SEC), and (SECC). In situ measurements subsurface moorings satellite observations reveal pronounced intraseasonal variability (ISV; 20–90 days) these currents in western (WTPO). amplitude ISV largest within equatorial band exceeding 20 cm s −1 decreases to ~10 NECC further 4–8 NEC SECC. power generally increases...
Abstract Despite its potential importance in the global climate system, mixing properties of North Pacific low‐latitude western boundary current system (LLWBC) remained unsampled until very recently. We report here on first measurements turbulence microstructure associated with these currents, made region tropical east Philippines. The results suggest that thermocline LLWBC is generally weak diapycnal diffusivity κ ρ ∼ O (10 −6 ) m 2 s −1 . This consistent predictions from internal wave‐wave...
The aim of this study was to investigate whether selenomethionine (SeMet) could attenuate intestinal injury in rabbits induced by ochratoxin A (OTA). Sixty 35-day-old IRA with similar weights were randomly assigned the control group, OTA group (0.2 mg OTA/kg b.w), OTA+ 0.2 mg/kg Se b.w + SeMet/kg feed), 0.4 feed) and 0.6 feed). examined after oral administration different doses SeMet for 21 days intragastrically administered 7 consecutive days. results showed that pretreatment protected...
Great progress has been made in the field of vascular tissue engineering, with some artificial grafts already exhibiting promising outcomes animal models. However, these studies were mostly conducted using healthy animals, which are not representative actual clinical demands. Indeed, patients who require graft implantation often accompanied by other comorbidities, such as hyperlipidaemia, hypertension and diabetes should also be taken into consideration when assessing potential that intended...
Abstract Time‐depth variations of the equatorial currents over upper 1000 m depth in western Pacific Ocean were directly measured by acoustic Doppler current profiler moorings at 2°N, 140°E and 4.7°N, during January–August 2014. Intraseasonal currents, with periods 37–73 days, observed encompassing North Equatorial Countercurrent (NECC), northern branch South Current (SEC), Undercurrent (EUC), Intermediate (EIC), (NICC), Subsurface (NESC). Compared previous studies based mainly on shipboard...
Major depressive disorder (MDD) is a leading cause of disability worldwide. A comprehensive understanding the molecular mechanisms this critical for therapy MDD. In study, it observed that deubiquitinase Mysm1 induced in brain tissues from patients with major depression and mice behaviors. The genetic silencing astrocytic an antidepressant-like effect alleviated osteoporosis mice. Furthermore, found knockdown led to increased ATP production activation p53 AMP-activated protein kinase (AMPK)....
Background As an opportunistic bacterial pathogen, Klebsiella pneumoniae (KP) is prone to causing a spectrum of diseases in rabbits when their immune system compromised, which poses threat rabbit breeding industry. Bacillus coagulans (BC), recognized as effective probiotic, confers variety benefits including anti-inflammatory and antioxidant properties. Aim The purpose this study was investigate whether dietary BC can effectively alleviate hepatic injury caused by KP. Methods In study, the...