A5024874229- Nanopore and Nanochannel Transport Studies
- Fuel Cells and Related Materials
- Microfluidic and Capillary Electrophoresis Applications
- Advanced biosensing and bioanalysis techniques
- Membrane-based Ion Separation Techniques
- Conducting polymers and applications
- Nanoplatforms for cancer theranostics
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Nanoparticle-Based Drug Delivery
- Ion-surface interactions and analysis
- Neuroscience and Neural Engineering
- Advanced Memory and Neural Computing
- Photodynamic Therapy Research Studies
- Porphyrin and Phthalocyanine Chemistry
Consejo Nacional de Investigaciones Científicas y Técnicas
2020-2024
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
2020-2024
Universidad Nacional de La Plata
2020-2024
Comisión Nacional de Energía Atómica
2017-2022
Centro Científico Tecnológico - Tucumán
2017-2020
Centro Atómico Constituyentes
2017
Nanofluidic field-effect transistors for tailored transport and bio-inspired functionalities: solid-state nanochannels can be smartly tuned by external potentials to induce open/closed states or promote ion selectivity in the same way as biological channels.
Electrochemical polymerization of ortho-aminophenol in asymmetric gold-coated polyethylene terephthalate (PET) single nanochannels yields voltage-gated nanofluidic diodes (nFET).
In this work, we present the construction and functional evaluation of a highly sensitive dopamine-responsive iontronic device by functionalization bullet-shaped track-etched single nanochannels in PET membranes with poly(3-aminobenzylamine).
Acetylcholinesterase-modified nanochannels are proposed as reliable and reproducible nanofluidic sensors for highly sensitive detection of acetylcholine. The operation mechanism relies on the use weak polyelectrolytes "chemical amplifiers" that adjust/reconfigure nanochannel surface charge in presence local pH changes induced by enzymatic reaction. Experimental results show acetylcholine can be transduced into measurable ionic signals with a low limit detection.
We present a reverse microemulsion synthesis procedure for incorporating methylene blue (MB), known FDA-approved type-II red-absorbing photosensitizer and 1O2 generator, into the matrix of hydrophobic-core/hydrophilic-shell SiO2 nanoparticles. Different conditions were explored with aim controlling entrapped-dye aggregation at high dye loadings in hydrophobic protective core; minimizing ensured highly efficient photoactive nanoentities production. Monitoring real time using UV-vis absorption...
Bioinspired borate-driven nanofluidic devices were constructed through the combination of atomic layer deposition (ALD) and silane chemistry into track-etched nanochannels.
We report the synthesis of a near-infrared (NIR) fluorescent pH probe with remarkable Stokes shift (∼135 nm) based on tricarbocyanine (Cy-PIP). The molecule was anchored to SiO2 nanoparticles (Cy-PIP@SiO2) and is capable monitoring changes within physiological range (pH 6-8). Cy-PIP@SiO2 were successfully internalized by HeLa cells as shown fluorescence confocal microscopy, while flow cytometry revealed fluctuations during endocytic pathway.
Nanofluidic channels in which the ionic transport can be modulated by application of an external voltage to nanochannel walls have been described as nanofluidic field effect transistors (nFETs) because their analogy with electrolyte-gated transistors. The creation nFETs is attracting increasing attention due possibility controlling ion using a non-invasive stimulus. In this work, we show that it possible extend actuation range supporting electrolyte "chemical effector". For aim, gold-coated...
Neurotransmitters are endogenous chemical messengers that play crucial roles in the transmission, enhancement and conversion of specific signals between neurons other cells considered biomarkers neurodegenerative diseases.[1] Neurodegenerative diseases cause progressive loss cognitive and/or motor function and, as life expectancy rises, they imply major challenges for societies with rapidly aging populations.[2] As a result, monitoring neurotransmitters is becoming increasingly relevant...