A5100385477- Nutrition, Genetics, and Disease
- Advanced Control Systems Optimization
- Plant tissue culture and regeneration
- Cancer-related molecular mechanisms research
- Sarcoidosis and Beryllium Toxicity Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer-related Molecular Pathways
- Cancer-related gene regulation
- Cancer Diagnosis and Treatment
- Transgenic Plants and Applications
- Hepatitis B Virus Studies
- Cancer, Hypoxia, and Metabolism
- interferon and immune responses
- Immunotherapy and Immune Responses
- Fault Detection and Control Systems
- Breast Lesions and Carcinomas
- Viral Infections and Vectors
- Wnt/β-catenin signaling in development and cancer
- Chronic Lymphocytic Leukemia Research
- Frailty in Older Adults
- Connective Tissue Growth Factor Research
- Hedgehog Signaling Pathway Studies
- Circular RNAs in diseases
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Research and Treatments
Shanghai Jiao Tong University
2023-2024
Shanghai First People's Hospital
2023-2024
Maimonides Medical Center
2023-2024
Chinese Center For Disease Control and Prevention
2023-2024
China Medical University
2023-2024
Zhejiang Chinese Medical University
2017
Epithelial‐mesenchymal transition (EMT) refers to the of epithelial cells into mesenchymal cells. Emerging evidence suggests that EMT is a key point in renal interstitial fibrosis (RIF). Traditional Chinese Medicine Shenqiwan (SQW) widely used clinical treatment chronic kidney disease, but underlying mechanism remains unclear. The purpose this study investigate effect SQW on and its association with TGF‐ β 1/Smads signaling pathway. A rat model adenine (150 mg/kg) was established...
Abstract Although many important advances have been made in the treatment of nasopharyngeal carcinoma (NPC) recent years, local recurrence and distant metastasis remain main factors affecting NPC prognosis. Biomarkers for predicting prognosis need to be urgently identified. Here, we used whole-exon sequencing (WES) determine whether PICK1 mutations are associated with NPC. Functionally, inhibits proliferation cells both vivo vitro. Mechanistically, inhibited expression proteins related...
Objective: To investigate the association of levels high sensitivity C-reactive protein (hs-CRP) with frailty and its components among elderly over 65 years old in 9 longevity areas China. Methods: Cross-sectional data from Health Ageing Biomarkers Cohort Study (HABCS, 2017-2018) were used included this study. Through questionnaire interview physical examination, information including demographic characteristics, behavior, diet, daily activity, cognitive function, health status was...
To explore the impact of whole blood organophosphate esters (OPEs) flame retardant exposure on thyroid function-related hormones in healthy older adults.
Rapid intrahepatic and distant metastasis of hepatocellular carcinoma (HCC) after locoregional treatment for early stage tumor is very rare. Descriptions spontaneous regression HCC exist in case reports, but its true mechanism unclear. Here, we describe a rapid dissemination with lung shortly localized RFA liver lesions, followed by spontaneous, sustained those lesions. We also show the detection cytotoxic T lymphocytes (CTLs) specific to hepatitis B antigens immune assay this patient....
<p>Supplementary Figure S1; Supplementary Tables S1-S4.</p>
<p>Supplementary Figure S1; Supplementary Tables S1-S4.</p>
<div>Abstract<p><b>Purpose:</b> This study evaluated the effects of black raspberries (BRBs) on biomarkers tumor development in human colon and rectum including methylation relevant suppressor genes, cell proliferation, apoptosis, angiogenesis, expression <i>Wnt</i> pathway genes.</p><p><b>Experimental Design:</b> Biopsies adjacent normal tissues colorectal adenocarcinomas were taken from 20 patients before after oral consumption...
<div>Abstract<p><b>Purpose:</b> This study evaluated the effects of black raspberries (BRBs) on biomarkers tumor development in human colon and rectum including methylation relevant suppressor genes, cell proliferation, apoptosis, angiogenesis, expression <i>Wnt</i> pathway genes.</p><p><b>Experimental Design:</b> Biopsies adjacent normal tissues colorectal adenocarcinomas were taken from 20 patients before after oral consumption...
Abstract Regulatory T (Treg) cells are a distinctive lineage of CD4+ as characterized by expression FoxP3 and CD25 markers. Treg involved in tumor development progression inhibiting antitumor immunity. Accumulation the microenvironment (TME) is often associated with an adverse prognosis multiple cancers also has implication for predicting response to immunotherapy. cell depletion strategy been explored preclinical clinical settings induce effective immune responses TME. CD25, high-affinity...