A5105670288- Carbon and Quantum Dots Applications
- Electromagnetic wave absorption materials
- Advanced Nanomaterials in Catalysis
- Advanced Antenna and Metasurface Technologies
- Crystallization and Solubility Studies
- Nanocluster Synthesis and Applications
- Metamaterials and Metasurfaces Applications
- X-ray Diffraction in Crystallography
- Advanced Photocatalysis Techniques
- Luminescence and Fluorescent Materials
- Asymmetric Synthesis and Catalysis
- Multiple Myeloma Research and Treatments
- Nuclear Materials and Properties
- Molecular Sensors and Ion Detection
- Cyclopropane Reaction Mechanisms
- Selenium in Biological Systems
- Oxidative Organic Chemistry Reactions
- Organic Chemistry Cycloaddition Reactions
- Ubiquitin and proteasome pathways
- Quantum Dots Synthesis And Properties
- Synthesis and biological activity
- Nanoplatforms for cancer theranostics
- Synthesis and Catalytic Reactions
- Nanoparticle-Based Drug Delivery
- Graphite, nuclear technology, radiation studies
Beijing Institute of Technology
2023-2025
Tianjin Medical University
2021-2025
Henan Normal University
2022-2025
Second Military Medical University
2025
Inner Mongolia Medical University
2022-2024
Shaanxi University of Science and Technology
2019-2024
Jiaxing University
2024
Weifang University
2024
Wuhan University of Technology
2023
Sichuan University
2023
With the advent of intelligent society and popularity electronic equipment, protection treatment electromagnetic (EM) radiation have become hot research topics all over world. Herein, novel 2D carbon-based nanoplates with uniformly embedded Co nanoparticles are prepared, unique hierarchical structure integrated magnetic-dielectric components. The obtained exhibit a wide range tunable EM properties (ε' for 3.38 to 34.67 ε″ 0.13 31.45) by manipulating dispersed states inside wax system, which...
Abstract Electromagnetic materials with adjustable dielectric and magnetic properties are constantly sought after in electronic industrial fields. In this study, an innovative strategy that customizes anchored Co‐based nanoparticles to optimize the behaviors is proposed for first time, enabling a controllable high‐efficiency evolution of macroscopic electromagnetic response (C/Co x T y ) nanoplates across X‐ray, light solar band gigahertz band. Specifically, band, C/Co 3 Se 4 high‐power loss...
Two coumarin-based boron complexes (HBN and MBN) with aggregation-induced emission were designed synthesized. The photophysical properties of the investigated in different solvents solid state. Results showed that inhibited C═N isomerization by N,O-chelated BF2 caused significant enhancement fluorescence THF. In particular, displayed red-shifted emissions (>60 nm) mixed CH3CN water because charge-transfer enhancement. state, bright red appeared at 650 nm (620 nm), a Stokes shift 170 nm....
Introduction: The anti-cancer potency of copper-doped carbon quantum dots (Cu-CDs) against breast cancer progression needs more detailed investigations. Methods: With urea and ethylene glycol applied as sources copper sulfate used a reactive dopant, Cu-CDs were synthesized in the current study by one-step hydrothermal synthesis method, followed characterization biocompatibility evaluations Cu-CDs. Subsequently, was confirmed these biochemical, molecular, transcriptomic assessments, including...
Curcumin (Cur) as a natural pigment and biological component, can be widely used in food beverages. However, the water insolubility of Cur significantly limits its applications. In this study, we prepared series nanocrystals via ultrasound-assisted method to improve solubility availability Cur. The results showed artemisia sphaerocephala krasch polysaccharide (ASKP), gum arabic (GA) wheat protein (WP) were outstanding stabilizers for nanocryatals except traditional agent, poloxamer 188...
Abstract Acquired chemoresistance to proteasome inhibitors is a major obstacle in managing multiple myeloma but key regulators and underlying mechanisms still remain be explored. We find that high level of HP1γ associated with low acetylation modification the bortezomib-resistant cells using SILAC-based acetyl-proteomics assay, higher positively correlated poorer outcomes clinic. Mechanistically, elevated HDAC1 deacetylates at lysine 5 consequently alleviates ubiquitin-mediated protein...
Self‐assembly “activated” carbon dot photosensitizer: a robust, NIR‐light responsive, and vein injectable nanosphere (CDNS) photosensitizer with 1 O 2 quantum yield of 0.45 under 671 nm laser irradiation has been developed through self‐assembly using individual CD as building units. This study develops the biomedical applications CD, highlights for designing well‐defined CD‐based photosensitizers, promotes future explorations this CDNS in nanomedical clinical applications.
This study aimed to develop novel rapid-acting antidepressants with sustained efficacy and favorable safety profiles. We designed synthesized a series of fluorine-containing scopolamine analogues evaluated their antidepressant potential. In vitro cytotoxicity assays showed that most these compounds exhibited minimal toxicity against neuronal non-neuronal mammalian cell lines (IC50 > 100 μM). The activities the were using tail suspension test, S-3a was identified as lead compound potent...
Basil seed-derived multi-heteroatom–doped porous carbons (BHPCs) are successfully synthesized by a facile gelation, followed moderate gel water/KOH coactivation process. The BHPC-700 prepared at relatively low KOH loading and activation temperature possesses large specific surface area (1178.3 m2 g−1), well-defined hierarchical micro/meso porosity, rich self-doping heteroatom functionalities (13.08 at% of oxygen, nitrogen, phosphorous, sulfur). Electrochemical tests demonstrate that the...
A new class of chiral bifunctional imidazole catalysts has been designed and synthesized, utilizing economical amino alcohols as precursors, significantly expanding the diversity N-1 position catalysts. These exhibit excellent substrate activation stereoselectivity control have successfully employed in asymmetric acylation 5-hydroxy-furanones/3-hydroxy-phthalides through dynamic kinetic resolution, producing a series furanone phthalide analogues featuring quaternary stereocenter. This...
Extracellular signal-regulated kinases (ERKs) are pivotal signaling molecules in the RAS-RAF-MEK-ERK pathway and have emerged as potential antitumor targets, providing a promising strategy for tumor therapy. Therefore, development of drugs targeting ERK protein has received extensive attention. Here, we developed compound library based on series novel aromatic urea-imidazole salt derivatives conducted phenotypic screening against various cancer cell lines. Notably, 21y exhibited high...
Abstract Selinexor is a First-in-Class XPO1 Inhibitor approved for relapsed or refractory multiple myeloma (RRMM), but the overall response rate remains unsatisfactory. The main mechanism by which kill MM cells to suppress export of tumor suppressor proteins and oncoprotein mRNAs, however other key underlying mechanisms need be investigated. Here, using proteomics nucleocytoplasmic separation assay, we discover that ring finger containing E3 ligase, RNF5, cargo substrate its...