A5015705305- Migraine and Headache Studies
- Gastroesophageal reflux and treatments
- Gastrointestinal motility and disorders
- Neurological and metabolic disorders
- Cardiovascular Syncope and Autonomic Disorders
- Infant Health and Development
- Restless Legs Syndrome Research
- Mobile Health and mHealth Applications
- Cannabis and Cannabinoid Research
- Respiratory and Cough-Related Research
- Metabolism and Genetic Disorders
- Telemedicine and Telehealth Implementation
- Pediatric Pain Management Techniques
- Diet and metabolism studies
- Trigeminal Neuralgia and Treatments
- Medical Education and Admissions
- Congenital gastrointestinal and neural anomalies
- Child Nutrition and Feeding Issues
- Racial and Ethnic Identity Research
- Neuroscience of respiration and sleep
- Maternal Mental Health During Pregnancy and Postpartum
- Health Systems, Economic Evaluations, Quality of Life
- Sympathectomy and Hyperhidrosis Treatments
- Vagus Nerve Stimulation Research
- Pathogenesis and Treatment of Hiccups
Medical College of Wisconsin
2013-2025
Hebei North University
2024
Takeda (United Kingdom)
2023
The Ohio State University
1999-2023
Children's Hospital of Wisconsin
2011-2021
Lurie Children's Hospital
2003
Nationwide Children's Hospital
1993-1999
ABSTRACT Objectives: Eosinophilic esophagitis (EoE) is an immune‐mediated chronic inflammatory disorder triggered by food antigen(s). A 6‐food elimination diet (SFED) excluding cow's milk, soy, wheat, egg, peanuts/tree nuts, and seafood has been shown to induce remission in a majority of children with EoE. The goal the present study was identify specific antigens responsible for eosinophilic esophageal inflammation EoE who had achieved histological SFED. Patients Methods: In this analysis,...
Cyclic vomiting syndrome (CVS) is a disorder noted for its unique intensity of vomiting, repeated emergency department visits and hospitalizations, reduced quality life. It often misdiagnosed due to the unappreciated pattern recurrence lack confirmatory testing. Because no accepted approach management has been established, task force was charged develop report on diagnosis treatment CVS based upon review medical literature expert opinion. The key issues addressed were diagnostic criteria,...
The aim of the study was to determine prevalence nausea in pediatric patients with pain-associated functional gastrointestinal disorders (FGIDs), examine effect on social and school functioning, applicability Rome III criteria.A total 221 (6-18 years age) chronic abdominal pain prospectively completed a demographic, history, symptom questionnaire adapted from Questionnaire Pediatric Gastrointestinal Symptoms (QPGS). 6-item, revised Migraine Disability Assessment Score tool used assess...
INTRODUCTION: The pathophysiology underlying cyclic vomiting syndrome (CVS) remains undefined. Scant data and distinct clinical features point to altered autonomic nervous system function. Autonomic signaling can be noninvasively assessed through cardiac indices of parasympathetic vagal regulation, which is reduced in children with disorders gut-brain interaction. We aimed examine dynamic regulation CVS compared that healthy controls (HC). METHODS: A total 31 evaluated a tertiary care center...
Background: Cyclic vomiting syndrome (CVS) is a disabling condition frequently refractory to pharmacologic therapy. The aim of this study was evaluate the effects noninvasive, auricular percutaneous electrical nerve field stimulation (PENFS) as prophylactic therapy for pediatric CVS. Methods: Children 8–18 years with drug-refractory CVS were prospectively enrolled from tertiary care clinic. Subjects received 6 consecutive weeks PENFS. severity quantified by episode frequency and duration...
To conduct a pilot study to evaluate the prevalence of psychiatric symptoms in children and adolescents with cyclic vomiting syndrome assess family history disorder.Little is known about comorbidity youth syndrome, periodic syndrome.Eighty-five parents, aged 3-18 years confirmed multidisciplinary clinic, completed age-appropriate Children's Symptom Inventory, questionnaire that screens for pediatric patients. Twenty-one 13-18 Youth's Report, self-report form this questionnaire. Sixty-two...
Children with cyclic vomiting syndrome (CVS) frequently suffer from disabling abdominal pain and comorbidities that impair quality of life. A noninvasive, auricular percutaneous electrical nerve field stimulation (PENFS) device is shown to be effective for in children disorders gut-brain interaction. We aimed determine the effects PENFS on pain, common comorbidities, life pediatric CVS.Children aged 8-18 years drug-refractory CVS were enrolled a prospective, open-label study receiving 6...
The clinical features of pediatric cyclic vomiting syndrome (CVS) often evolve over time. Many patients develop a constellation chronic symptoms that suggest autonomic nervous system (ANS) dysfunction during adolescence. We aimed to determine the proportion children with CVS who rather than episodic consistent ANS dysfunction.Retrospective chart review ages 0-18 years followed in an outpatient tertiary care center. Patients completed standardized questionnaires at intake and follow-up...
Cyclic vomiting syndrome (CVS) is a common, frequently disabling, 'functional' condition characterized by recurring, stereotypical attacks of intense nausea, vomiting, and lethargy, with the essential absence these symptoms between episodes. Although pathogenesis CVS yet unexplained, evidence has accumulated which suggest pathogenic roles for stress-related, autonomic, neuroendocrine, mitochondrial factors. The objective this pilot study was to elucidate mechanism(s) identifying genes...
Nausea frequently co-exists with functional abdominal pain disorders (FAPDs) and may be linked to a higher disease burden. This study aimed prospectively compare multisystem symptoms, quality of life, functioning in FAPDs without nausea.Adolescents ages 11-18 years fulfilling Rome III criteria for FAPD were grouped by the presence or absence chronic nausea. Subjects completed validated instruments assessing nausea (Nausea Profile Questionnaire = NPQ), life (Patient-Reported Outcome...
Purpose This mixed-methods study quantified and characterized incidents of microaggressions experienced by Asian American medical students. The authors report on their impact suggest improvements to create a more equitable supportive learning environment.