A5019945109- Advanced Mathematical Identities
- Analytic Number Theory Research
- Antibiotics Pharmacokinetics and Efficacy
- Advanced Combinatorial Mathematics
- Pneumonia and Respiratory Infections
- Medical Imaging and Pathology Studies
- Prostate Cancer Diagnosis and Treatment
- Advanced Algebra and Geometry
- Cancer Diagnosis and Treatment
- Analytical Chemistry and Chromatography
- Prostate Cancer Treatment and Research
- Cancer Treatment and Pharmacology
- Breast Cancer Treatment Studies
- Intensive Care Unit Cognitive Disorders
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Advanced MRI Techniques and Applications
- Anesthesia and Sedative Agents
- Epilepsy research and treatment
- AI in cancer detection
- Biopolymer Synthesis and Applications
- Gastric Cancer Management and Outcomes
- Inhalation and Respiratory Drug Delivery
- MRI in cancer diagnosis
- Helicobacter pylori-related gastroenterology studies
National Taiwan University
2018-2025
Tokyo Women's Medical University
2015-2025
St. Marianna University School of Medicine
2025
Funabashi Municipal Medical Center
1993-2023
Kyushu University
2018-2020
Meiji (Japan)
2019-2020
Japan Medical Association
2019
National Center for Theoretical Sciences
2018
National Center for Theoretical Sciences, Mathematics Division
2018
Kyoto University
2013-2017
beta1,3-N-acetylglucosaminyltransferase 2 (beta3GnT2) is a polylactosamine synthase that synthesizes backbone structure of carbohydrate structures onto glycoproteins. Here we generated beta3GnT2-deficient (beta3GnT2(-/-)) mice and showed on N-glycans was markedly reduced in their immunological tissues. In WT mice, present CD28 CD19, both known immune costimulatory molecules. However, levels these molecules were beta3GnT2(-/-) mice. T cells lacking more sensitive to the induction...
Abstract Aim Post‐intensive care unit (ICU) patients often experience physical or mental dysfunction. This study aims to investigate the relationship between sleep disturbances and problems in discharged from ICU hospital wards, using both subjective objective measures. Methods Patients admitted for at least 72 h November 2021 June 2022 were included study. On seventh day after discharge, we conducted an assessment electroencephalogram‐based mobile sleep‐monitoring device. self‐administered...
Abstract Jacobson developed a counterpart of Galois theory for purely inseparable field extensions in positive characteristic. In his theory, certain type derivations replace the role generators groups. This article provides convenient criterion determining such dimension two. We also present examples demonstrating efficiency our criterion.
We have demonstrated that an Arabidopsis serine/arginine rich-like protein, atSR45a, interacts with other splicing factors and its expression is markedly induced by high-light stress, suggesting the involvement of atSR45a in regulation stress-responsive alternative splicing. A whole-genome tiling array identified genes regulated comparing gene profiles wild-type knockout (KO-sr45a) plants under stress. The levels genomic regions within 217 were significantly altered KO-sr45a compared plants....
The Glasgow prognostic score, a marker of systemic inflammation, is associated with clinical outcomes in different cancers including prostate cancer. However, there no evidence for the relationship between high-sensitivity modified score (Hs-mGPS) cancer and its prognosis. This study aimed to investigate significance Hs-mGPS castration-resistant (CRPC) treated docetaxel. We retrospectively analyzed datasets from 131 CRPC patients who received docetaxel treatment at Chiba University Hospital...
ABSTRACT. Patients who have renal failure and are on dialysis therapy experience serious complications caused by low-molecular-weight uremic toxin proteins normally filtered glomeruli metabolized proximal tubule cells (PTC). Dialysis-related amyloidosis is one such complication induced systemic deposition of amyloid derived from 12-kD β<sub>2</sub>-microglobulin (β<sub>2</sub>-m). Despite the use high-flux membrane hemodialysis devices direct absorbent columns, removal β<sub>2</sub>-m...
Podocytes have been shown to express classical cadherins in the early stage of glomerulogenesis, but it remains unclear whether podocytes normal and pathological conditions adult stage. To address this question, rat neonate, puromycin aminonucleoside (PAN) nephrosis were examined by immunofluorescence microscopy using antibodies against α‐ β‐catenins anti‐pan‐cadherin antibody, immunoelectron anti‐α‐catenin antibody. In all reacted with junctional complex S‐shaped body The staining...
Leaves develop as flat lateral organs from the indeterminate shoot apical meristem. The establishment of polarity along three-dimensional axes, proximal–distal, medial–lateral, and adaxial–abaxial is crucial for growth normal leaves. mutations ASYMMETRIC LEAVES1 (AS1) AS2 Arabidopsis thaliana cause defects in repression state axis formation Although many have been identified that enhance as1 as2 mutants, roles causative genes leaf development are still unknown. In this study, we found...
Abstract Background The role of testosterone as a prognostic factor for castration‐resistant prostate cancer treated with docetaxel in Japan was investigated. Methods A total 164 patients who received treatment at Chiba University Hospital and an affiliated hospital were retrospectively analyzed. Testosterone other clinical factors the start evaluated respect to overall survival progression‐free survival. Results Of patients, 69 had high‐volume tumors. median prostatic‐specific antigen 27.0...
Abstract We present a case of chemotherapy‐induced leukopenic septic shock treated with veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO). Although the indication for VA‐ECMO in immunosuppressed states remains controversial, her relatively young age and slightly increasing leukocyte count led to induction resulted recovery.
The mucosal blood volume in 20 to 24 different regions of stomach was estimated by reflectance spectrophotometry during endoscopy, and an image showing distribution made two-dimensional computer color graphics with the aid a personal computer. In 55 normal controls, (EMBV) greater corpus mucosa than antral mucosa, less lesser curvature curvature. anterior posterior walls almost same. 15 patients active gastric ulcers angular region, EMBV decreased all stomach. 37 healing ulcers, increased,...
Let $K$ be a number field. Fix finite set of analytic functions $\mathbf{f}_{\infty}:=\{f_{1,\infty}(x),\ldots,f_{s,\infty}(x) \}$ defined on $\{x\in \mathbb{C} \mid |x|>1\}$ (resp. $\mathbb{C}_p$-valued $\mathbf{f}_{p}:=\{f_{1,p}(x),\ldots,f_{s,p}(x) \mathbb{C}_p |x|_p>1\}$). For $\beta\in K$, we denote the $K$-vector space spanned by $f_{1,\infty}(\beta),\ldots,f_{s,\infty}(\beta)$ $V_K(\mathbf{f}_{\infty},\beta)$ $f_{1,p}(\beta),\ldots,f_{s,p}(\beta)$ $V_K(\mathbf{f}_{p},\beta)$). In this...
Posterior reversible encephalopathy syndrome is characterized by neurological symptoms with leukoencephalopathy detectable computed tomography (CT) and magnetic resonance (MR) imaging. We here present a patient no history of hypertension who, after being transferred back to the ward undergoing total hysterectomy under general anesthesia, had several seizures lost consciousness. was suspected on basis brain CT images clinical findings. She treated respiratory support, sedative drugs,...
Background Although the various advantages of clinical information systems in intensive care units (ICUs), such as (ICISs), have been reported, their role preventing medical errors remains unclear. Objective This study aimed to investigate changes incidence and type ICU before after ICIS implementation a setting where hospital electronic record system is already use. Methods An was introduced general university hospital. After step-by-step lasting 3 months, used for all patients starting...
The relationship between polysomnography-based objective sleep and delirium in the intensive care unit (ICU) is inconsistent across studies, suggesting limitations manually determining stage of critically ill patients. We objectively measured 24-h using a single-channel electroencephalogram (SleepScope [SS]) an under-mattress monitor (Nemuri SCAN [NSCAN]), both which have independent algorithms that automatically determine wakefulness. Eighteen patients (median age, 68 years) admitted to ICU...
Abstract Objectives The purpose of this study was to investigate intraductal carcinoma the prostate (intraductal carcinoma) and significant cancer (SC) in patients with small tumor volume (<0.5 cm 3 ) prostatectomy specimens. Methods Data from 639 undergoing radical between April 2006 December 2017 at Chiba University Hospital 2 affiliated institutions were retrospectively reviewed. Tumor specimens measured, a less than 0.5 , presence SC examined. defined as one that did not meet...