A5085804113- Cardiac, Anesthesia and Surgical Outcomes
- Enhanced Recovery After Surgery
- Anesthesia and Pain Management
- Colorectal Cancer Surgical Treatments
- Surgical site infection prevention
- Nausea and vomiting management
- Clinical practice guidelines implementation
- Hospital Admissions and Outcomes
- Homelessness and Social Issues
- Hip and Femur Fractures
- Diversity and Career in Medicine
- Inflammatory Bowel Disease
- Geriatric Care and Nursing Homes
- Colorectal and Anal Carcinomas
- Pain Management and Opioid Use
- Patient Safety and Medication Errors
- Medical Malpractice and Liability Issues
- Nutrition and Health in Aging
- Microscopic Colitis
- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- Innovations in Medical Education
- Diverticular Disease and Complications
- Emergency and Acute Care Studies
- Healthcare Policy and Management
University of California, San Francisco
2016-2025
Johns Hopkins University
2014-2023
Color (United States)
2023
Highland Hospital
2023
University of California, Los Angeles
2019-2023
The Ohio State University Wexner Medical Center
2023
Agency for Healthcare Research and Quality
2018-2023
American College of Surgeons
2012-2023
National Patient Safety Foundation
2015-2023
Johns Hopkins Medicine
2013-2022
Significance We demonstrate, to our knowledge for the first time, that bacterial biofilms are associated with colorectal cancers, one of leading malignancies in United States and abroad. Colon biofilms, dense communities bacteria encased a likely complex matrix contact colon epithelial cells, nearly universal on right tumors. Most remarkably, biofilm presence correlates tissue invasion changes biology enhanced cellular proliferation, basic feature oncogenic transformation occurring even...
Hospital readmission is emerging as a quality indicator by the state, federal, and private payors with goal of denying payment for select readmissions.We designed study to measure rate, cost, risk factors hospital after colorectal surgery.We reviewed commercial health insurance records 10,882 patients who underwent surgery over 7-year period (2002-2008).All undergoing colon and/or rectal resection ages 18 64 were included.The 30-day 90-day rates, number readmissions per patient, median...
Colorectal cancer (CRC) remains the third most common worldwide, with a growing incidence among young adults. Multiple studies have presented associations between gut microbiome and CRC, suggesting link risk. Although CRC continue to profile larger patient cohorts increasingly economical rapid DNA sequencing platforms, few been identified, in part due limitations taxonomic resolution differences analysis methodologies. Complementing these is newly recognized phenomenon that bacterial...
Overtreatment is a cause of preventable harm and waste in health care. Little known about clinician perspectives on the problem. In this study, physicians were surveyed prevalence, causes, implications overtreatment.2,106 from an online community composed doctors American Medical Association (AMA) masterfile participated survey. The survey inquired extent overutilization, as well solutions, for Main outcome measures included: percentage unnecessary medical care, most commonly cited reasons...
In 2010, national payers announced they would begin using patient satisfaction scores to adjust reimbursements for surgical care.To determine whether is independent from process measures and hospital safety.We compared the performance of hospitals that participated in Patient Satisfaction Survey, Centers Medicare & Medicaid Services Surgical Care Improvement Program, employee Safety Attitudes Questionnaire.Thirty-one US hospitals. PARTICIPANTS Patients employees.There were no interventions...
Abstract Background Enhanced Recovery After Surgery (ERAS) protocols reduce length of stay, complications and costs for a large number elective surgical procedures. A similar, structured approach appears to improve outcomes, including mortality, patients undergoing high‐risk emergency general surgery, specifically laparotomy. These are the first consensus guidelines optimal care these using an ERAS approach. Methods Experts in aspects management patient were invited contribute by...
Importance Informed consent is a critical component of patient care before invasive procedures, yet it frequently inadequate. Electronic forms have the potential to facilitate comprehension if they provide information that readable, accurate, and complete; not known large language model (LLM)-based chatbots may improve informed documentation by generating accurate complete easily understood patients. Objective To compare readability, accuracy, completeness LLM-based chatbot- vs...
Objectives: To measure the effect of obesity on surgical site infection (SSI) rates and to define cost SSIs in patients undergoing colorectal surgery.Design, Setting, Patients: This is a retrospective cohort study 7020 colectomy using administrative claims data from 8 Blue Cross Shield insurance plans.Patients who had total or segmental for colon cancer, diverticulitis, inflammatory bowel disease between January 1, 2002, December 31, 2008, were included. Main Outcome Measures:We compared...
IL17-producing Th17 cells, generated through a STAT3-dependent mechanism, have been shown to promote carcinogenesis in many systems, including microbe-driven colon cancer. Additional sources of IL17, such as γδ T become available under inflammatory conditions, but their contributions cancer development are unclear. In this study, we modeled Th17-driven tumorigenesis by colonizing Min(Ap) (c+/-) mice with the human gut bacterium, enterotoxigenic Bacteroides fragilis (ETBF), investigate link...
Enterotoxigenic Bacteroides fragilis (ETBF), a molecular subclass of the common human commensal, B. fragilis, has been associated with inflammatory bowel disease. ETBF colitis is characterized by activation Stat3 and Th17 immune response in colonic mucosa. This study was designed to investigate time course cellular distribution ETBF-colonized mice.
Each year, the National Cancer Database (NCDB) collects and analyzes data used in reports to support research, quality measures, Commission on program accreditation. Because models generate these have been historically stable, year-to-year variances attributed changes within cancer rather than modeling. submissions 2020 were anticipated be significantly different from prior years because of COVID-19 pandemic. This study involved a validation analysis observed expected NCDB comparison with...