A5058170092- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Infectious Diseases and Mycology
- Antibiotic Use and Resistance
- Actinomycetales infections and treatment
- Antimicrobial Resistance in Staphylococcus
- Zoonotic diseases and public health
- Identification and Quantification in Food
- Viral gastroenteritis research and epidemiology
- Essential Oils and Antimicrobial Activity
- Diagnosis and treatment of tuberculosis
- Milk Quality and Mastitis in Dairy Cows
- Phytochemicals and Medicinal Plants
- Vibrio bacteria research studies
- Urinary Tract Infections Management
- Bacterial biofilms and quorum sensing
- Respiratory viral infections research
- Pneumocystis jirovecii pneumonia detection and treatment
- Seed and Plant Biochemistry
- Global Health and Surgery
- Ethnobotanical and Medicinal Plants Studies
- Animal Disease Management and Epidemiology
Sokoine University of Agriculture
2015-2025
Leipzig University
2015-2017
Instituut voor Tropische Geneeskunde
2011
Non-tuberculous mycobacteria (NTM) are increasingly reported worldwide associated with human disease. Defining the significance of NTM in settings endemic tuberculosis (TB) requires discrimination from TB suspect patients. Correct and timely identification will impact both therapy epidemiology TB-like diseases. The present study aimed at determining frequency diversity among suspects northeastern Tanzania. A cross-sectional was conducted between November 2012 through January 2013. Seven...
Abstract Background Multidrug resistance (MDR) is a major clinical problem in tertiary hospitals Tanzania and jeopardizes the life of neonates critical care units (CCUs). To better understand methods for prevention MDR infections, this study aimed to determine, among other factors, role MDR-Gram-negative bacteria (GNB) contaminating neonatal cots hands mothers as possible transmission bacteremia at Bugando Medical Centre (BMC), Mwanza, Tanzania. Methods This cross-sectional, hospital-based...
The proportions and similarities of extended-spectrum β-lactamase (ESBL) producing K. pneumoniae (ESBL-KP) E. coli (ESBL-EC) carrying multiple ESBL genes is poorly known at our setting. This study investigated the existence (blaCTX-M, blaTEM, blaSHV) among ESBL-KP ESBL-EC concurrently isolated from clinical, colonization, contamination samples neonatology units in Mwanza-Tanzania. Twenty 55 presumptive ESBL-KP, respectively, a previous archived -80 °C were successfully recovered for this...
This cross-sectional study was conducted between January and June 2020, in five large poultry slaughter slabs Dar es Salaam, Tanzania. Purposive sampling used to select broilers spent layers, from which meat cloaca swabs were collected determine the occurrence of multidrug resistant (MDR) Escherichia coli. Identification isolates done using API 20E, antimicrobial susceptibility testing performed as per CLSI (2018) guidelines. EBSL (CTX-M, TEM, SHV) plasmid mediated quinolone (qnrA, qnrB,...
Introduction Salmonella, one of the most frequent foodborne bacteria, is linked to 155,000 annual mortality and 93.8 million illnesses. Rampant use antibiotic agents combat Salmonellosis in poultry has contributed emergence resistance against commonly used antibiotics. Methodology A cross-section study was conducted between January June 2023. Purposive sampling select farms, faecal droppings were collected determine occurrence multidrug-resistant (MDR) Salmonella spp. Samples examined for...
Introduction Salmonella, one of the most frequent foodborne bacteria, is linked to 155,000 annual mortality and 93.8 million illnesses. Rampant use antibiotic agents combat Salmonellosis in poultry has contributed emergence resistance against commonly used antibiotics. Methodology A cross-section study was conducted between January June 2023. Purposive sampling select farms, faecal droppings were collected determine occurrence multidrug-resistant (MDR) Salmonella spp. Samples examined for...
Introduction Salmonella, one of the most frequent foodborne bacteria, is linked to 155,000 annual mortality and 93.8 million illnesses. Rampant use antibiotic agents combat Salmonellosis in poultry has contributed emergence resistance against commonly used antibiotics. Methodology A cross-section study was conducted between January June 2023. Purposive sampling select farms, faecal droppings were collected determine occurrence multidrug-resistant (MDR) Salmonella spp. Samples examined for...
Introduction. Salmonella is one of the most prevalent foodborne bacteria, posing a significant global health concern and responsible for ~155,000 deaths 93.8 million human illnesses annually. The rampant use antibiotic agents to combat salmonellosis in poultry has contributed emergence resistance against commonly used antibiotics. Methodology. cross-sectional study was conducted between January June 2023 across three districts Dar es Salaam region, Tanzania. isolates were detected confirmed...
A national tuberculosis (TB) drug resistance survey in Tanzania.To compare the performance of Genotype® MTBDRplus line-probe assay (LPA) on smear-positive sputum specimens with conventional culture and isoniazid (INH) plus rifampicin (RMP) susceptibility testing (DST).Mycobacterium isolates tested at Tanzanian Central TB Reference Laboratory (CTRL) were submitted for quality assurance phenotypic DST to its supranational reference laboratory (SRL), together ethanol-preserved LPA DST.Only 321...
Pulmonary nocardiosis mimic pulmonary tuberculosis in most clinical and radiological manifestations. In Tanzania, where is one of the major public health threat impact as cause human disease remains unknown. The objective present study was to isolate identify Nocardia isolates recovered from TB suspects Northeastern, Tanzania by using biochemical molecular methods. involved 744 sputum samples collected 372 four periphery diagnostic centers in Tanzania. Twenty patients were diagnosed having...
Background and Aim: One Health (OH) approach is crucial for the effective management of emerging re-emerging infectious diseases other public health threats. A meta-analysis was conducted to explore benefits challenges encountered in practical implementation multisectoral coordination fight against threats identify similarities between countries cooperation across sectors OH. Materials Methods: To relevant studies published globally 2010 2023, a literature search online using Google Scholar...
To determine the prevalence and risk factors associated with drug resistance tuberculosis (TB) at facility-base level in Tanga, Tanzania. A total of 79 Mycobacterium (MTB) isolates included study were collected from among 372 (312 new 60 previously treated) TB suspects self-referred to four clinics during a prospective conducted November 2012 January 2013. Culture susceptibility test was performed institute medical microbiology epidemiology infectious diseases, University hospital, Leipzig,...
Background: The role of nontuberculous mycobacteria (NTM) in tuberculosis (TB) diagnosis is well documented many developing settings. However, this has not been the case resource poor settings like Tanzania. This study aimed at understanding NTM and management TB Tanzania.Methods: A cross‑sectional was conducted Tanga, Patients with symptoms suggestive self-referred to health care facilities were recruited. Two sputum samples collected for standard direct smear microscopy. Culture performed...
In Zambia, poultry is a rapidly increasing sector contributing 4.8% of the Agricultural Gross Domestic Product (GDP), thus providing significant income-generating activity. Worldwide, major reservoir Salmonella with an incidence extended-spectrum beta-lactamase (ESBL) producing strains. ESBLs are enzymes produced by bacteria and capable inactivating wide range beta-lactam antibiotics. enterica serovars Enteritidis Typhimurium most important foodborne serotypes in many countries, infecting...
The plants
The antimicrobial resistance catastrophe is a growing global health threat and predicted to be worse in developing countries. Phages for Global Health (PGH) training scientists these regions isolate relevant therapeutic phages pathogenic bacteria within their locality, thus contributing making phage technology universally available.During the inaugural PGH workshop East Africa, samples from Ugandan municipal sewage facilities were collected two novel Escherichia coli lytic isolated...
The aim of this study was to evaluate the antimicrobial potential and perform phytochemical screening ethanolic (70%) leaf extracts Bauhinia rufescens Ocimum basilicum root Salvadora persica, three plants used for treatment numerous diseases in Chad.The extraction made a ratio 70% volume ethanol against 30% distilled water.The yields obtained leaves rufescens, basilicum, persica roots were respectively 20, 17, 8.8%.With disc diffusion method, results assessment revealed that active...
Introduction Salmonella, one of the most frequent foodborne bacteria, is linked to 155,000 annual mortality and 93.8 million illnesses. Rampant use antibiotic agents combat Salmonellosis in poultry has contributed emergence resistance against commonly used antibiotics. Methodology A cross-section study was conducted between January June 2023. Purposive sampling select farms, faecal droppings were collected determine occurrence multidrug-resistant (MDR) Salmonella spp. Samples examined for...
Abstract Knowledge about One Health approach and its importance among the practitioners community in addressing health threats is of paramount important. This study aimed to assess knowledge actors on multi-sectoral coordination risks selected regions Tanzania. A descriptive was conducted from June August 2023 Arusha, Iringa Dodoma where quantitative qualitative data were collected 101 participants representing line ministries sub-national regional district levels. Descriptive analysis done...
The emergence of methicillin-resistant Staphylococcus aureus (MRSA) creates a serious public health concern due to its ability colonize and infect humans animals. This cross-sectional study investigated the prevalence, antibiotic susceptibility pattern S. MRSA isolated from bovine raw milk in Njombe region, Tanzania. A total 470 samples, including 389 samples collected at farm level, 57 bulk milk-can collection centers, 24 swab cans. were cultured on mannitol salt agar, presumptive colonies...