- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Identification and Quantification in Food
- Wildlife Ecology and Conservation
- Genetic and phenotypic traits in livestock
- Malaria Research and Control
- Environmental DNA in Biodiversity Studies
- Drug Transport and Resistance Mechanisms
- Gut microbiota and health
- Amphibian and Reptile Biology
- Antimicrobial Peptides and Activities
- Metabolomics and Mass Spectrometry Studies
- Hair Growth and Disorders
- Species Distribution and Climate Change
- Forensic and Genetic Research
- Animal Ecology and Behavior Studies
- Physiological and biochemical adaptations
- HIV/AIDS drug development and treatment
- Bat Biology and Ecology Studies
- Genetic Mapping and Diversity in Plants and Animals
- Aquaculture disease management and microbiota
- Bioenergy crop production and management
- Plant Gene Expression Analysis
- Chromosomal and Genetic Variations
- T-cell and B-cell Immunology
Northeast Forestry University
2016-2025
State Forestry and Grassland Administration
2013-2025
Ministry of Agriculture and Rural Affairs
2024-2025
Agro-Environmental Protection Institute
2024-2025
Northwest A&F University
2025
BGI Research
2024
Yunnan Institute of Parasitic Diseases
2016-2023
Obuda University
2023
China University of Geosciences
2023
Guizhou Academy of Agricultural Sciences
2016-2021
The development and regulation of hair are widely influenced by biological rhythm signals. Melatonin plays a crucial role as messenger in transmitting signals, its impact on has been well documented. During the process follicle reconstruction, stem cells (HFSCs) most important cell type, but regulatory effect melatonin state HFSCs is still not fully understood. Therefore, it necessary to conduct more comprehensive characterization effects cells. research results indicate that express...
The availability of viral entry factors is a prerequisite for the cross-species transmission severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Large-scale single-cell screening animal cells could reveal expression patterns genes in different hosts. However, such exploration SARS-CoV-2 remains limited. Here, we perform single-nucleus RNA sequencing 11 non-model species, including pets (cat, dog, hamster, and lizard), livestock (goat rabbit), poultry (duck pigeon), wildlife...
Abstract The South China tiger ( Panthera tigris amoyensis , SCT) is the most critically endangered subspecies of due to functional extinction in wild. Inbreeding depression observed among captive population descended from six wild ancestors, resulting high juvenile mortality and low reproduction. We assembled characterized first SCT genome an improved Amur P. t. altaica AT) named AmyTig1.0 PanTig2.0. two genomes are continuous comprehensive any yet reported at chromosomal level. By using...
Abstract Utilization of faeces has long been a popular approach for genetic and ecological studies wildlife. However, the success molecular marker genotyping genome resequencing is often unpredictable due to insufficient enrichment endogenous DNA in total faecal that dominated by bacterial DNA. Here, we report simple cheap method named PEERS predominantly lyse animal cells over bacteria using sodium dodecyl sulphate so as discharge into liquid phase before By brief centrifugation, with...
The gastrointestinal tracts of animals are home to large, complex communities microbes. compositions these ultimately reflect the coevolution microorganisms with their animal host and influenced by living environment, diet immune status host. Gut microbes have been shown be important for human disease health, but little research exists in gut microbiome Amur tiger, which is one most endangered species world.In this study, we present use whole-metagenome shotgun sequencing analyze composition...
The formation of animal breeds usually begins with a small subsample from their ancestral population. Deleterious mutations accumulate in the population under genetic drift, inbreeding, and artificial selection during development maintenance traits desired by humans. White raccoon dogs are among most popular farmed dogs, but white more susceptible to disease have lower reproductive ability. However, accumulation deleterious this breed is largely unknown. By analyzing comparing whole-genome...
The illegal ivory trade has led to a sharp decline in wild elephant populations recent decades, while mammoth (Mammuthus primigenius) products have increasingly flooded the marketplace, complicating identification efforts by frontline law enforcement. Existing methods face several challenges, including inconsistent accuracy due sample quality, high costs, slow turnaround times, and destructive requirements. Currently, there is lack of fast, convenient, highly effective solution address these...
The hair coat is an adaptive evolutionary trait unique to mammals, aiding them in adapting complex environmental challenges. Although some of the factors involved regulating follicle development have been characterized, further in-depth research still needed. Retinoic acid receptor-related orphan receptor alpha (RORA), as a member nuclear family, highly regulation cellular states. Previous studies shown that autophagy plays significant role development. This study uses rat stem cells (HFSCs)...
Hair is a prominent physiological feature of many animals that can be easily and non-invasively sampled. However, most previous studies have focused on human hair, animal hair has not been widely used as DNA source in genetic evolutionary studies. Analysing the quality more challenging than because it varies across different species influenced by storage conditions. To address this gap our knowledge, study systematically evaluated various samples. Our findings show lightly medullated hairs,...
High-alkalinity water bodies can disrupt normal ammonia metabolism in fish, leading to poisoning. In China, there exists a highly tolerant group of Amur ide (Leuciscus waleckii) that survive extreme alkaline lakes with alkalinity up 53.57 mM (pH 9.6), making it an excellent model for elucidating the high-alkalinity tolerance mechanism fish. We have discovered this species has evolved special excretion maintain efflux environments. Compared freshwater forms ide, protein RHBG plays prominent...
The problem of anti-malarial drug resistance is a long-term challenge faced by malaria control in Yunnan Province. Recently, the detection rates chloroquine-resistant molecular markers (Plasmodium falciparum chloroquine resistant transporter, Pfcrt) and artemisinin-resistant (P. kelch13 gene, ork13) were 85% 35%, respectively. To understand association k13 gene mutation with artemisinin cases, difference differentiation between two populations phenotype on cases Myanmar analysed this study....
The raccoon dog (Nyctereutes procyonoides) is an invasive canid species native to East Asia with several distinct characteristics. Here, we report a chromosome-scale genome of the high contiguity, completeness, and accuracy. intact taste receptor genes, expanded gene families, positively selected genes related digestion, absorption, foraging, detoxification likely support omnivory dogs. Several dog-specific mutations in TDRD6 ZP3 may explain their reproductivity. Enriched GO terms energy...
Abstract Trade in ivory from extant elephant species namely Asian ( Elephas maximus ), African savanna Loxodonta africana ) and forest cyclotis is regulated internationally, while the trade extinct of Elephantidae, including woolly mammoth, unregulated. This distinction creates opportunity for laundering trading as mammoth ivory. The existing morphological molecular genetics methods do not reliably distinguish source items that lack clear identification characteristics or which quality...
The hair, an exclusive keratinized dermal appendage in mammals, stands as a quintessential outcome of adaptive evolution, conferring resilience against adverse environmental conditions. ontogenesis the coat displays pronounced rhythmic pattern, with hair follicle stem cells (HFSCs) emerging pivotal facilitators reconstitution. retinoic acid-related orphan receptor alpha, nuclear extensive involvement regulation cellular physiological states, exerts its functions predominantly through...