A5062707294- Malaria Research and Control
- Intergenerational Family Dynamics and Caregiving
- Health disparities and outcomes
- Drug Transport and Resistance Mechanisms
- Family Dynamics and Relationships
- Demographic Trends and Gender Preferences
- Pharmacogenetics and Drug Metabolism
- Neuroinflammation and Neurodegeneration Mechanisms
- Single-cell and spatial transcriptomics
- Global Health Care Issues
- Conducting polymers and applications
- Electrochemical sensors and biosensors
- Hepatitis B Virus Studies
- HIV/AIDS drug development and treatment
- MXene and MAX Phase Materials
- Social Policy and Reform Studies
- Migration and Labor Dynamics
- Employment and Welfare Studies
- 2D Materials and Applications
- Pharmacological Effects of Natural Compounds
- Suicide and Self-Harm Studies
- Work-Family Balance Challenges
- Cell Image Analysis Techniques
- Electrochemical Analysis and Applications
- Advanced Battery Materials and Technologies
Huazhong University of Science and Technology
2021-2025
Cotton Research Institute
2024-2025
Shanxi Agricultural University
2024-2025
Center for Excellence in Brain Science and Intelligence Technology
2022-2025
Chinese Academy of Sciences
2022-2025
University of Copenhagen
2021-2024
Westlake University
2024
Tongji Hospital
2024
Yunnan Institute of Parasitic Diseases
2016-2023
University of Chinese Academy of Sciences
2023
Elucidating the cellular organization of cerebral cortex is critical for understanding brain structure and function. Using large-scale single-nucleus RNA sequencing spatial transcriptomic analysis 143 macaque cortical regions, we obtained a comprehensive atlas 264 transcriptome-defined cell types mapped their distribution across entire cortex. We characterized layer region preferences glutamatergic, GABAergic, non-neuronal types, as well regional differences in cell-type composition...
The severe dependence of traditional phase change materials (PCMs) on the temperature-response and lattice deficiencies in versatility cannot satisfy demand for using such complex application scenarios. Here, we introduced metal ions to induce self-assembly MXene nanosheets achieve their ordered arrangement by combining suction filtration rapid freezing. Subsequently, a series MXene/ K
As the power core of an electric vehicle, performance lithium-ion batteries (LIBs) is directly related to vehicle quality and driving range. However, charge–discharge cycling are affected by temperature. Excessive temperature can cause internal short circuits even lead safety issues, such as thermal runaway. The separator plays a crucial role in protecting battery from regular operation, preventing direct touch between cathode anode while allowing transport lithium ions. In this study, we...
Claustrum orchestrates brain functions via its connections with numerous regions, but molecular and cellular organization remains unresolved. Single-nucleus RNA sequencing of 227,750 macaque claustral cells identified 48 transcriptome-defined cell types, most glutamatergic neurons similar to deep-layer insular neurons. Comparison macaque, marmoset, mouse transcriptomes revealed macaque-specific types. Retrograde tracer injections at 67 cortical 7 subcortical regions defined four distinct...
Climate change is likely to worsen the food security situation through its impact on production, which may indirectly affect fertility behaviour. This study examines direct and indirect effects of climate (e.g., temperature precipitation) via production major crops, as well their short- long-term total rate (TFR) in Bangladesh. We used structural equation modelling (SEM) perform path analysis distinguish influence security. also applied error correction model (ECM) analyze time-series data...
The current study aims to illustrate male female suicide rate ratios in the world and explore correlations between labour force participation rates (FLPR) of both genders. Further, whether relationship FLPR vary according human capabilities a given country are examined. Using data obtained from World Health Organization Statistical Information System, gender 70 countries illustrated. Based on level Human Development Index (HDI) FLPR, Bayesian Criteria (BIC) was used determine optimal number...
Despite much attention paid to the surging divorce rate in China, knowledge on patterns and trends at subnational level is still very limited. This study aims systematically explore social economic factors affecting between 1990 2015 provincial from a tempo–spatial perspective. Traditional fixed effects panel regression spatial autoregression are adopted. Divorce maps demonstrated great variations levels of across provinces, highlighting diversities obscured national trend. It further...
Abstract Global profile of gene expression at single-cell resolution remains to be determined for primates. Using a recently developed technology (“Stereo-seq”), we have obtained comprehensive spatial transcriptome map the whole-brain level cynomolgus monkeys, with ∼600 genes per cell 10 μm-thick coronal sections (up 15 cm 2 in size). Large-scale single-nucleus RNA-seq analysis ∼1 million cells helped identify types corresponding Stereo-seq profiles, providing 3-D type atlas monkey brain....
Background/Objectives: GDSL lipase is crucial for plant growth and the response to environmental stress. While gene families have been identified in some plants, a comprehensive genome-wide identification analysis M. domestica lacking. Methods: In this study, we 131 MdGDSLs belonging four subfamilies, distributed across 17 chromosomes genome. Results: The molecular weights (MWs) of these range from 14.44 83.26 kDa, with isoelectric points (PI) spanning 4.32 10.09. Members within same...
The problem of anti-malarial drug resistance is a long-term challenge faced by malaria control in Yunnan Province. Recently, the detection rates chloroquine-resistant molecular markers (Plasmodium falciparum chloroquine resistant transporter, Pfcrt) and artemisinin-resistant (P. kelch13 gene, ork13) were 85% 35%, respectively. To understand association k13 gene mutation with artemisinin cases, difference differentiation between two populations phenotype on cases Myanmar analysed this study....
Over the past few decades, level of divorce, measured by crude divorce rate (CDR), has increased dramatically in both East and West, but recently appeared to fall or off some countries. To investigate whether recent decline stabilisation CDRs reflects real trends risk, a decomposition analysis was conducted on changes over 20 years two western three Asian countries, namely, UK, Australia, Taiwan, South Korea, Singapore. The following is observed: UK Australia 1990s, Taiwan Korea 2000s,...
This paper presents a novel WLAN-based indoor localization algorithm (i.e., HED) to combat the environmental dynamics by tolerating sequence disorders caused AP (access point) changes, while harvesting from bursting number of available wireless resources. Via extensive real-world experiments lasting for over 6 months, we show superiority our HED in terms accuracy and complexity two state-of-the-art solutions that are also designed resist dynamics, i.e., FreeLoc LCS (Longest Common...
Abstract In urban China, the social welfare system and family structure have changed dramatically, while gender norms are still deep-rooted, particularly among older adults. Under this social, demographic cultural context, study aims to take a gender-specific perspective investigate whether how moderates roles of pensions, support self-care ability on adults’ life satisfaction. Based survey data collected from 2,047 adults aged 65 years over in China 2018, multiple linear regressions were...
Abstract The PANI/Au 0 nanocomposite films were successfully prepared on glassy carbon electrode (GCE) using a simple alternate adsorption of water soluble polyaniline (PANI) and ${{\rm AuCl}{{- \hfill \atop 4\hfill}}}$ . growth the was monitored by UVVis spectroscopy cyclic voltammetry. in‐situ reduced in film due to redox interaction between PANI , without extra reductant. ultrafine Au nanoparticles with size 2–4 nm observed transmission electron spectroscopy. existence zero‐valence...
Abstract Background According to China’s Malaria Eradication Action Plan, malaria cases diagnosed and reported by health authorities at the county level must be further re-confirmed provincial laboratories. The Yunnan Province Diagnostic Reference Laboratory (YPMDRL) began synchronous implementation of microscopic examinations nested polymerase chain reaction (nested-PCR) testing re-test initially county-level laboratories evaluate consistency Plasmodium species identified between YPMDRL...
Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep vein thrombosis (DVT) occurs more frequently in cancer patients than the general population. A retrospective cross-sectional study was carried out with solid tumor complicated VTE admitted to Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science Technology between January 1st, 2008 December 31th, 2017. The incidence hospitalized 1.8%, twice non-cancer patients. annual cancer-associated...
Abstract Immunotherapy has been recommended as a second-line treatment only for high microsatellite instability or DNA mismatch repair deficiency advanced pancreatic cancer in National Comprehensive Cancer Network guidelines. Here, we report case with good response to immunotherapy proficiency. A 55-year-old woman diagnosed cT4N1M1 (liver, lung) who harbored ERBB2 mutations tumor mutation burden (TMB) underwent multiple therapies and survived 19 months. partial was observed when the patient...