A5076291929- Advanced Radiotherapy Techniques
- Cardiac Imaging and Diagnostics
- Chemotherapy-induced cardiotoxicity and mitigation
- Head and Neck Cancer Studies
- Radiation Therapy and Dosimetry
- Prostate Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Oral health in cancer treatment
- Glioma Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Prostate Cancer Treatment and Research
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- RNA Research and Splicing
- Cancer Cells and Metastasis
- Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Atrial Fibrillation Management and Outcomes
- Sarcoma Diagnosis and Treatment
- Ultrasound and Hyperthermia Applications
- Organophosphorus compounds synthesis
- Synthesis of Tetrazole Derivatives
- Breast Implant and Reconstruction
- History of Medicine Studies
- Pediatric Pain Management Techniques
Clinique Pasteur
2017-2024
Inserm
2024
Centre de recherche en Epidémiologie et Santé des Populations
2024
Université de Poitiers
2017-2020
Centre Hospitalier Universitaire de Poitiers
2010-2017
Centre de Radiothérapie Bayard
2010-2011
Institut Català de la Salut
2001
Intra-individual heterogeneity of cardiac exposure is an issue in breast cancer (BC) radiotherapy that was poorly considered previous cardiotoxicity studies mainly based on mean heart dose (MHD). This dosimetric study analyzes the distribution individually-determined radiation doses to and its substructures including coronary arteries evaluate whether MHD a relevant surrogate parameter for these substructures.Data were collected from BACCARAT prospective included left or right unilateral BC...
Radioresistant glioblastoma stem cells (GSCs) contribute to tumor recurrence and identification of the molecular targets involved in radioresistance mechanisms is likely enhance therapeutic efficacy. This study analyzed DNA damage response following ionizing radiation (IR) 10 GSC lines derived from patients. was quantified by Comet assay repair effectors were assessed Low Density Array. The effect RAD51 inhibitor, RI-1, evaluated comet annexin V assays. While all displayed efficient...
Abstract Background Breast cancer (BC) radiotherapy (RT) can induce cardiotoxicity, with adverse events often observed many years after BC RT. Subclinical left ventricular (LV) dysfunction be detected early RT global longitudinal strain (GLS) measurement based on 2D speckle-tracking echocardiography. This 6-month follow-up analysis from the BACCARAT prospective study aimed to investigate association between cardiac radiation doses and subclinical LV GLS reduction. Methods The patient group...
Background Atrial fibrillation (AF) after radiotherapy (RT) in patients with breast cancer (BC) is a relatively new and understudied topic. AF can increase the risk of stroke other serious cardiovascular complications, compromising patients’ quality life survival. Screening AF, both asymptomatic symptomatic forms, therefore essential for optimal management. Objective The aim Watch Your Heart After Radiotherapy Breast Cancer (WATCH) study to assess incidence (symptomatic or asymptomatic)...
Glioblastoma (GBM) represents the most common and lethal primary malignant brain tumor. The standard treatment for glioblastoma patients involves surgical resection with concomitant radio chemotherapy. Despite today's clinical protocol, prognosis remains very poor a median survival of 15 months. Tumor resistance recurrence is strongly correlated subpopulation highly radioresistant invasive cells termed Stem Cells (GSCs). transcription factor STAT3 has been found to be constitutively...
Objective: The severity of breakthrough cancer pain (BTcP) impacts patients' quality life, increases the risk anxiety and depression, lowers functional capacities, may lead to poor compliance with treatments. aim current study was assess, in a real-life setting, patient satisfaction fentanyl-pectin-nasal-spray (FPNS) for BTcP management head neck (H&N) patients treated by radiotherapy. Materials Methods: This non-interventional, prospective conducted 92 adult H&N-cancer undergoing...
<title>Abstract</title> <bold>Background: </bold>Radiation therapy (RT) for breast cancer (BC) can result in subtle cardiac dysfunction that occur early after treatment. In 2022, the European Society of Cardiology (ESC) published first guidelines cardio-oncology with a harmonized definition therapy-related (CTRCD). The aim this study was to evaluate CTRCD occurrence over 24 months follow-up RT BC patients and analyze association radiation exposure. <bold>Methods: </bold>The prospective...
Radiation therapy (RT) for breast cancer (BC) can result in subtle cardiac dysfunction that occur early after treatment. In 2022, the European Society of Cardiology (ESC) published first guidelines cardio-oncology with a harmonized definition therapy-related (CTRCD). The aim this study was to evaluate CTRCD occurrence over 24 months follow-up RT BC patients and analyze association radiation exposure. prospective monocentric BACCARAT included treated without chemotherapy, aged 40–75 years,...
<title>Abstract</title> <bold>Background</bold> Post-radiotherapy atrial fibrillation (AF) in breast cancer (BC) patients is a relatively new and understudied topic. AF can increase the risk of stroke other serious cardiovascular complications, compromising patients' quality life survival. Detection AF, both asymptomatic symptomatic forms, therefore essential for optimal management. The objective WATCH study to assess incidence (symptomatic or asymptomatic) occurring throughout 5-years...
<sec> <title>BACKGROUND</title> Post-radiotherapy atrial fibrillation (AF) in breast cancer (BC) patients is a relatively new and understudied topic. AF can increase the risk of stroke other serious cardiovascular complications, compromising patients' quality life survival. Detection AF, both asymptomatic symptomatic forms, therefore essential for optimal management. </sec> <title>OBJECTIVE</title> The aim WATCH study to assess incidence (symptomatic or asymptomatic) occurring throughout...