A5046429385- Radiation Dose and Imaging
- Radioactivity and Radon Measurements
- Radioactive contamination and transfer
- Effects of Radiation Exposure
- Risk Perception and Management
- Air Quality and Health Impacts
- Radiation Therapy and Dosimetry
- Nuclear and radioactivity studies
- Occupational and environmental lung diseases
- Chemotherapy-induced cardiotoxicity and mitigation
- Health Systems, Economic Evaluations, Quality of Life
- Graphite, nuclear technology, radiation studies
- Carcinogens and Genotoxicity Assessment
- Cardiac Imaging and Diagnostics
- Global Cancer Incidence and Screening
- Acute Lymphoblastic Leukemia research
- Advances in Oncology and Radiotherapy
- Health, Environment, Cognitive Aging
- Cardiovascular Function and Risk Factors
- Advanced Radiotherapy Techniques
- Healthcare Systems and Practices
- Risk and Safety Analysis
- Breast Cancer Treatment Studies
- Health, Medicine and Society
- Childhood Cancer Survivors' Quality of Life
Institut de Radioprotection et de Sûreté Nucléaire
2015-2024
National Institute for Radiological Protection
2005-2023
Institut National de Santé Publique du Québec
2023
Laboratoire de Chimie Physique - Matière et Rayonnement
2003-2017
CEA Paris-Saclay - Etablissement de Fontenay-aux-roses
2000-2016
Helmholtz Zentrum München
2016
Federal Office for Radiation Protection
2016
Tampere University
2016
University of Manchester
2016
Radiation Effects Research Foundation
2016
BackgroundThere is much uncertainty about the risks of leukaemia and lymphoma after repeated or protracted low-dose radiation exposure typical occupational, environmental, diagnostic medical settings. We quantified associations between exposures leukaemia, lymphoma, multiple myeloma mortality among radiation-monitored adults employed in France, UK, USA.MethodsWe assembled a cohort 308 297 workers for at least 1 year by Atomic Energy Commission, AREVA Nuclear Cycle, National Electricity...
<b>Study question</b> Is protracted exposure to low doses of ionising radiation associated with an increased risk solid cancer? <b>Methods</b> In this cohort study, 308 297 workers in the nuclear industry from France, United Kingdom, and States detailed monitoring data for external were linked death registries. Excess relative rate per Gy dose mortality cancer was estimated. Follow-up encompassed 8.2 million person years. Of 66 632 known deaths by end follow-up, 17 957 due cancers. answer...
Abstract Objective To evaluate the effect of protracted low dose, dose rate exposure to ionising radiation on risk cancer. Design Multinational cohort study. Setting Cohorts workers in nuclear industry France, UK, and US included a major update International Nuclear Workers Study (INWORKS). Participants 309 932 with individual monitoring data for external total follow-up 10.7 million person years. Main outcome measures Estimates excess relative per gray (Gy) mortality from Results The study...
Recent epidemiological results suggested an increase of cancer risk after receiving computed tomography (CT) scans in childhood or adolescence. Their interpretation is questioned due to the lack information about reasons for examination. Our objective was estimate related CT scans, and examine how cancer-predisposing factors (PFs) affect assessment radiation-related risk. The cohort included 67 274 children who had a first scan before age 10 years from 2000 2010 23 French departments....
Intra-individual heterogeneity of cardiac exposure is an issue in breast cancer (BC) radiotherapy that was poorly considered previous cardiotoxicity studies mainly based on mean heart dose (MHD). This dosimetric study analyzes the distribution individually-determined radiation doses to and its substructures including coronary arteries evaluate whether MHD a relevant surrogate parameter for these substructures.Data were collected from BACCARAT prospective included left or right unilateral BC...
Positive associations between external radiation dose and non-cancer mortality have been found in a number of published studies, primarily populations exposed to high-dose, high-dose-rate ionizing radiation. The goal this study was determine whether associated with large pooled cohort nuclear workers low-dose accumulated at low rates. comprised 308,297 from France, United Kingdom States. average cumulative equivalent tissue depth 10 mm [Hp(10)] 25.2 mSv. In total, 22% the were deceased by...
There is considerable scientific interest in associations between protracted low-dose exposure to ionizing radiation and the occurrence of specific types cancer.
The International Commission on Radiological Protection (ICRP) has embarked a review and revision of the system that will update 2007 general recommendations in ICRPPublication 103. This is beginning process take several years, involving open transparent engagement with organisations individuals around world. While robust performed well, it must adapt to address changes science society remain fit for purpose. aim this paper encourage discussions which areas might gain greatest benefit from...
The linear no-threshold (LNT) model was introduced into the radiological protection system about 60 years ago, but this and its use in radiation are still debated today. This article presents an overview of results on effects exposure to low linear-energy-transfer radiobiology epidemiology accumulated over last decade discusses their impact LNT assessment radiation-related cancer risks at doses. knowledge acquired past 10 years, both epidemiology, has reinforced scientific In radiobiology,...
The inhalation of radon, a well-established human carcinogen, is the principal-and omnipresent-source radioactivity exposure for general population most countries. Scientists have thus sought to assess lung cancer risk associated with indoor radon. Our aim here this in France, using all available epidemiologic results and performing an uncertainty analysis.We examined exposure-response relations derived from cohorts miners joint analyses residential case-control studies considered...
Radon is recognized as a public health concern for indoor exposure. Precise quantification derived from occupational exposure in miners still needed estimating the risk and factors that modify dependence on cumulated The present paper reports relationship between radon lung cancer French Czech cohorts of uranium (n = 10,100). Miners these two are characterized by low levels (average less than 60 WLM) protracted over long period (mean duration 10 years) good quality individual estimates (95%...
A combined analysis of three case-control studies nested in European uranium miner cohorts was performed to study the joint effects radon exposure and smoking on lung cancer death risk. Occupational history data were available from cohorts. Smoking information reconstructed using self-administered questionnaires occupational medical archives. Linear excess relative risk models adjusted for used estimate associated with exposure. The includes 1046 cases 2492 controls detailed status. ERR/WLM...
The aim of this work is to study the risk childhood acute leukemia (AL) around French nuclear power plants (NPPs). nationwide Geocap case-control included 2,753 cases diagnosed in mainland France over 2002-2007 and 30,000 contemporaneous population controls. last addresses were geocoded located 19 NPPs. used distance NPPs a dose-based geographic zoning (DBGZ), based on estimated dose bone marrow related NPP gaseous discharges. An odds ratio (OR) 1.9 [1.0-3.3], 14 cases, was evidenced for...
The increasing use of CT scans in the paediatric population raises question a possible health impact ionising radiation exposure associated with scans. aim this study was to describe pattern early childhood.In 14 major French radiology departments, children undergoing at least 1 scan before age 5, between 2000 and 2006, were included. For each examination, absorbed organ doses calculated.43% 27 362 cohort aged less than year during their first exposure, 9% being month. mean number...
Radiation dose to the eye lens is a crucial issue for interventional cardiologists (ICs) who are exposed during procedures they perform. This paper presents retrospective assessment of cumulative doses ICs enrolled in O'CLOC study Occupational Cataracts and Lens Opacities Cardiology. Information on workload catheterisation laboratory, radiation protection equipment, per procedure reduction factors associated with eye-protective equipment were considered. For 129 at an average age 51 had...