A5022102897- Environmental Toxicology and Ecotoxicology
- Toxic Organic Pollutants Impact
- Pharmaceutical and Antibiotic Environmental Impacts
- Aquaculture Nutrition and Growth
- Fish Ecology and Management Studies
- Gut microbiota and health
- Parasite Biology and Host Interactions
- Heavy Metal Exposure and Toxicity
- Drug Transport and Resistance Mechanisms
- Fish Biology and Ecology Studies
- Organ Transplantation Techniques and Outcomes
- Pharmacogenetics and Drug Metabolism
- Nutritional Studies and Diet
- Culinary Culture and Tourism
- Nutrition, Health and Food Behavior
- Liver Disease Diagnosis and Treatment
- Oil Spill Detection and Mitigation
- Glutathione Transferases and Polymorphisms
- Liver physiology and pathology
- Reproductive biology and impacts on aquatic species
- Carcinogens and Genotoxicity Assessment
- Alcohol Consumption and Health Effects
- Effects and risks of endocrine disrupting chemicals
- Microscopic Colitis
- Aquaculture disease management and microbiota
Finnish Institute for Health and Welfare
2023-2025
University of Helsinki
2025
University of Eastern Finland
1995-2004
NOAA National Marine Fisheries Service
2000
NOAA National Marine Fisheries Service Northwest Fisheries Science Center
2000
National Oceanic and Atmospheric Administration
2000
Estonian University of Life Sciences
1999
University of Tartu
1999
Abstract Background and aims Alcohol remains a global risk factor for non-communicable diseases with the gut microbiome emerging as novel elucidator. We investigated how associates alcohol on population level, if there is mediation reflected in health outcomes, functional potential related. Methods Our sample consisted of 4575 shallow-shotgun sequenced fecal samples from FINRISK 2002 cohort (25-74yrs., 52.5% women). (g 100% alcohol/week) use was self-reported. Diversity differential species...
Population-based studies on the associations of plant-based foods, red meat or dairy with gut microbiome are scarce. We examined whether consumption foods (vegetables, potatoes, fruits, cereals), and processed (RPM) (fermented milk, cheese, other products) related to in Finnish adults.
Dyslipidemia is treated effectively with statins, but treatment has the potential to induce new-onset type-2 diabetes. Gut microbiota may contribute this outcome variability. We assessed associations of gut diversity and composition statins. Bacterial statin-associated diabetes (T2D) risk were also prospectively evaluated.
The biologic effects of the oil shale industry on caged rainbow trout (Oncorhynchus mykiss) as well feral perch (Perca fluviatilis) and roach (Rutilus rutilus) were studied in River Narva northeast Estonia. passes mining processing area thus receives elevated amounts polycyclic aromatic hydrocarbons (PAHs), heavy metals, sulfates. chemical load monitored by measuring cytochrome P4501A (CYP1A)-dependent monooxygenase (MO) activities [7-ethoxyresorufin O-deethylase aryl hydrocarbon hydroxylase...
Significant seasonal differences in intra‐ and interorgan prevalence, abundance distribution of rodlet cells (RC) were observed freshwater bream caught May August 1997 from a PCB‐polluted lake, Lake Kernaala, Finland. In May, the majority RCs liver seen blood vessel endothelium, while most located epithelium intrahepatic biliary ducts. kidney, significant increase columnar collecting ducts was to August. spleen extremely rare but frequently endothelium splenic vessels gill intestine, found...
We assessed the intrastrain and interstrain variability of cytochrome P450 enzyme activities conjugation reactions different rainbow trout (Oncorhynchus mykiss) strains. The study protocol was divided into two parts: in separate experiments, monooxygenase (7-ethoxyresorufin O-deethylase, EROD) (glutathione S-transferase, GST; UDP-glucuronosyl transferase, UDPGT) were measured from liver kidney samples commonly used breeds. In preliminary study, differences basal biotransformation detected...
The biologic effects of the oil shale industry on caged rainbow trout (Oncorhynchus mykiss) as well feral perch (Perca fluviatilis) and roach (Rutilus rutilus) were studied in River Narva northeast Estonia. passes mining processing area thus receives elevated amounts polycyclic aromatic hydrocarbons (PAHs), heavy metals, sulfates. chemical load monitored by measuring cytochrome P4501A (CYP1A)-dependent monooxygenase (MO) activities [7-ethoxyresorufin O-deethylase aryl hydrocarbon hydroxylase...
Background and objectives: The consumption of fermented milk products has been considered beneficial for health. moderate use can also be part environmentally sustainable diets. Findings on gut microbiome associations, however, have inconsistent, studies conducted population-based samples are scarce. We examined whether the (e.g., yoghurt, buttermilk, curdled milk) is related to individual microbiota diversity (alpha diversity), compositional differences in (beta or bacterial species...
Significant seasonal differences in intra- and interorgan prevalence, abundance distribution of rodlet cells (RC) were observed freshwater bream caught May August 1997 from a PCB-polluted lake, Lake Kernaala, Finland. In May, the majority RCs liver seen blood vessel endothelium, while most located epithelium intrahepatic biliary ducts. kidney, significant increase columnar collecting ducts was to August. spleen extremely rare but frequently endothelium splenic vessels gill intestine, found...