Miro Jakovljević
A5030621556- Tryptophan and brain disorders
- Resilience and Mental Health
- Stress Responses and Cortisol
- Schizophrenia research and treatment
- Child and Adolescent Health
- Child and Adolescent Psychosocial and Emotional Development
- Diet and metabolism studies
- Cardiac Health and Mental Health
- Pharmacological Effects and Toxicity Studies
- Healthcare professionals’ stress and burnout
- Suicide and Self-Harm Studies
- Birth, Development, and Health
- Bipolar Disorder and Treatment
- Health and Conflict Studies
- Neurotransmitter Receptor Influence on Behavior
- Technology and Human Factors in Education and Health
- Religion, Spirituality, and Psychology
- Education, Law, and Society
- Mental Health and Psychiatry
- Migration, Health and Trauma
- Parkinson's Disease and Spinal Disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Epilepsy research and treatment
- Posttraumatic Stress Disorder Research
- Electroconvulsive Therapy Studies
University Hospital Centre Zagreb
1997-2024
University of Zagreb
1997-2024
Institute for Medical Research and Occupational Health
2024
Croatian Academy of Sciences and Arts
2018
Klinika za psihijatriju Vrapče
2013
Abstract Study Objectives Sleep problems are common, serving as both a predictor and symptom of posttraumatic stress disorder (PTSD), with these bidirectional relationships well established in the literature. While sleep phenotypes PTSD moderately heritable, there has been paucity investigation into potential genetic overlap between PTSD. Here, we estimate correlations multiple (including insomnia symptoms, duration, daytime sleepiness, chronotype) PTSD, using results from largest...
The aim of the present study was to explore differences in serum CRP, IL-6, TNF-α, ACTH and cortisol among patients with major depressive disorder or without metabolic syndrome (MS) compared a healthy control group.The MDD group consisted 80 (mean age 50.03±9.55 years). recruited from hospital personnel it 40 examinees 47.20±7.99 All who participated were diagnosed using MINI questionnaire, Hamilton rating scale for depression. Diagnosis set by NCEP ATP III criteria.Examinees depression but...
The gamma-aminobutyric acid (GABA) neurotransmitter system has been implicated in the pathogenesis of mood disorders. To test this hypothesis we carried out an association study between a dinucleotide repeat polymorphism GABAA receptor α5 subunit gene and bipolar unipolar Our results suggest possible involvement but not disorder.
Abstract Posttraumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited. We performed a multi-ancestry meta-analysis of genome-wide association across 1,222,882 individuals European ancestry (137,136 cases) and 58,051 admixed with African Native American (13,624 cases). identified 95 significant loci (80 novel). Convergent...
The aim of this study is to investigate the association gene variations monoamine oxidase A (MAOA) and serotonin transporter solute carrier family 6 member 4 (SLC6A4) with posttraumatic stress disorder (PTSD) severity coping strategies in patients war related PTSD.The included 747 individuals who had experienced trauma South Eastern Europe conflicts between 1991 1999. Genotyping MAOA VNTR SLC6A4 tandem repeat polymorphism combination rs25531 was done 719 participants: 232 females 487 males....
Post-traumatic stress disorder (PTSD) is a related which can occur in an individual after exposure to traumatic event. It most commonly co-occurs with depression. The two disorders share not only overlapping symptoms, but also genetic diathesis. aim of this study was investigate the potential role single nucleotide polymorphisms (SNPs) serotonergic candidate genes 5-hydroxytryptamine receptor 1A (HTR1A) and tryptophan hydroxylase 2 (TPH2) pathogenesis PTSD comorbid psychopathology.719 (487...
Posttraumatic stress disorder (PTSD) is a highly frequent and disabling psychiatric condition among war-affected populations. The FK506-binding protein 5 (FKBP5) gene the corticotropin-releasing hormone receptor 1 (CRHR1) have previously been implicated in an elevated risk of peritraumatic dissociation PTSD development. Our aim was to investigate association between FKBP5 CRHR1 genotypes diagnosis severity individuals who were affected by Balkan wars during 1990s.This study included...
Stress is implicated as a risk factor for numerous illnesses in humans, putatively part mediated by biological responses to stress, such elevated cortisol concentrations. The theory of genetic homoeostasis suggests that individual heterozygosity facilitates compensation environmental stresses. We hypothesized ameliorates the response given level perceived reflected lower plasma concentrations.We examined role association between psychological stress and morning concentrations 854 individuals...
Previous research showed inconsistent results concerning a possible association between solute carrier family 6 member 3 (SLC6A3) gene polymorphisms and dopamine symptoms of posttraumatic stress disorder (PTSD). Several studies also indicate that the myelin basic protein (MBP) is importance in etiology several psychiatric disorders. The aim this study was to investigate relation distinct SLC6A3 MBP with PTSD whether genotypes contribute symptom severity.The included 719 individuals who had...