A5004716597- Acute Myeloid Leukemia Research
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Cutaneous lymphoproliferative disorders research
- Chronic Myeloid Leukemia Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Viral-associated cancers and disorders
- Hemoglobinopathies and Related Disorders
- Histone Deacetylase Inhibitors Research
- RNA modifications and cancer
- Eosinophilic Disorders and Syndromes
- Protein Degradation and Inhibitors
- COVID-19 Clinical Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Cancer-related molecular mechanisms research
- Fungal Infections and Studies
- CAR-T cell therapy research
- Long-Term Effects of COVID-19
- Acute Lymphoblastic Leukemia research
- CNS Lymphoma Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- Sarcoma Diagnosis and Treatment
- T-cell and Retrovirus Studies
- SARS-CoV-2 and COVID-19 Research
National and Kapodistrian University of Athens
2015-2025
University General Hospital Attikon
2015-2024
National Technical University of Athens
2023
Children's Hospital of Philadelphia
2017-2022
University of Cambridge
2020-2022
National Institute for Health Research
2022
Hellenic Open University
2022
Drexel University
2022
Hellenic Oncology Research Group
2018-2020
Albert Einstein College of Medicine
2015
Unraveling the pathophysiology of COVID-19 disease is crucial importance for designing treatment. The purpose this study to investigate effects on erythrocytes (RBCs) and correlate findings with severity.
MicroRNA-155-5p (miR-155-5p) is a proinflammatory, oncogenic miRNA, involved in various physiological processes, including hematopoiesis, immunity, inflammation, and cell lineage differentiation. It regulates important transcription factors, such as E2F2, hypoxia-inducible factor 1 (HIF1), FOXO3. Recently, the dysregulation of miR-155-5p expression has been linked to chronic lymphocytic leukemia (CLL) pathogenesis. In this research study, we investigated potential diagnostic prognostic value...
Background Lenalidomide improves erythropoiesis in patients with low/intermediate-1 risk myelodysplastic syndrome and interstitial deletion of the long arm chromosome 5 [del(5q)]. The aim this study was to explore effect lenalidomide treatment on reserves functional characteristics bone marrow hematopoietic progenitor/precursor cells, stromal cells peripheral blood lymphocytes del(5q).Design Methods We evaluated number clonogenic potential erythroid/myeloid/megakaryocytic progenitor using...
Brentuximab vedotin (BV) was approved as a therapy for mycosis fungoides (MF) based on the ALCANZA trial. Little real-world data, however, are available.To evaluate efficacy and safety of BV in patients with MF/Sézary Syndrome (SS) variable CD30 positivity cohort to explore potential predictors response.Data from 72 MF/SS across nine EORTC (European Organization Research Treatment Cancer) centres were included. The primary endpoint proportion with: overall response (ORR), ORR lasting over 4...
Although most patients with classical Hodgkin's lymphoma (CHL) are cured, a significant minority refractory to treatment. The investigation of biological markers could improve the predictive capacity clinical staging systems. aim our study was detect B-cell differentiation and transcription factors in CHL order define subgroups different histogeneses prognoses.We evaluated 107 cases for BCL6, CD79a, MUM1/IRF4 BOB.1, OCT.2 expression by immunohistochemistry. Statistical analysis performed...
We determined the Human Blood Index (HBI) of malaria mosquito vectors in Equatorial Guinea. used a polymerase chain reaction (PCR)-based methodology to identify blood meal sources engorged mosquitoes. observed high HBI values, indicating that these are highly anthropophilic despite intensive intradomicillary application residual insecticides. Our results suggest estimating can be relatively simple and easy way evaluate efficacy antimalaria interventions where an diversion non-human hosts may...
Cerebral malaria (CM) remains a significant cause of morbidity and mortality in children sub-Saharan Africa. CM has been associated with increased brain volume, seen on neuroimaging studies. To examine the potential role blood metabolites inflammatory mediators volume Malawian CM, an association study was performed between plasma metabolites, cytokine levels phospholipase A2 (PLA2) activity volume. The metabolomics analysis demonstrated arachidonic acid other lysophospholipids to be...
Mycosis fungoides (MF) is an indolent cutaneous lymphoma with excellent prognosis at early stages and much poorer outcome during disease progression. Old age, male sex folliculotropism have been proposed as relevant prognostic factors; however, their exact effect remains debatable.To evaluate MF indicators survival rates in a Greek population.Prognostic variables affecting were studied 473 patients diagnosed treated by two academic referral centres Greece. Kaplan-Meier estimates used to...