- Retinal Diseases and Treatments
- Mosquito-borne diseases and control
- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Ubiquitin and proteasome pathways
- Retinal Development and Disorders
- Viral Infections and Vectors
- Vector-borne infectious diseases
- Reproductive Physiology in Livestock
- Fungal Biology and Applications
- Cerebrovascular and genetic disorders
- Wnt/β-catenin signaling in development and cancer
- Glaucoma and retinal disorders
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Fungal Plant Pathogen Control
- Birth, Development, and Health
- Cancer-related molecular mechanisms research
- Analytical Methods in Pharmaceuticals
- Synthesis of Organic Compounds
- Reconstructive Surgery and Microvascular Techniques
- Cholinesterase and Neurodegenerative Diseases
- Hip and Femur Fractures
- Analytical Chemistry and Chromatography
- Innovations in Medical Education
Beijing University of Chinese Medicine
2019-2025
Huazhong Agricultural University
2024-2025
Hunan University
2025
Guiyang Medical University
2022-2024
University of Electronic Science and Technology of China
2024
XinHua Hospital
2024
Shanghai Jiao Tong University
2024
Zhejiang University of Technology
2024
Chengdu Institute of Biology
2024
Chinese Academy of Sciences
2024
Potassium permanganate (KMnO4) is a commercially available antiseptic used in bovine intrauterine lavage to manage postpartum infections. Lipopolysaccharides (LPS) are well-studied for their ability induce inflammation and oxidative stress. While KMnO4 known cause significant irritation, stress, toxicity uterine tissues, its transcriptional impact potential inducing similar molecular damage as LPS have not been fully explored. In this study, we induced stress the tissues of Sprague-Dawley...
Although Japanese encephalitis virus genotype Ib (JEV GIb) has replaced JEV GIII as the dominant in endemic areas of Asia, no GIb been isolated from JE cases and natural mosquitoes at same time an outbreak JE. In this study, we conducted virological molecular biological laboratory tests on case samples (serum/cerebrospinal fluid) locally collected mosquito 2018 Ningxia, China. The result IgM antibody detection showed that 96% (67/70) suspected were laboratory-confirmed cases. Of local...
During the process of human civilization, owning household pets has become increasingly popular. However, dogs and cats may be reservoirs or vectors transmissible diseases to humans. Confronted with overpopulation pets, traditional contraception methods, surgical methods sterilization, for animals are used, namely, ovariohysterectomy orchidectomy. Therefore, a simple, nonsurgical, controllable, more effective less expensive method is highly desirable. In this study, we show that in situ...
Abstract Background The incidence of osteoporosis increases with age. Frailty is a distinct characteristic seen in older patients. Poor sleep quality common elderly individuals. However, there are few studies on the correlation between frailty and patients China. Methods This cross-sectional study was conducted from December 8, 2020, to April 30, 2021. A total 247 who met inclusion exclusion criteria were recruited outpatient departments at West China Hospital. self-designed demographic data...
Oxidative stress is a significant factor affecting reproductive efficiency in dairy cows, contributing to conditions such as endometritis that impair fertility and milk production. This study investigates the molecular mechanisms by which bta-let-7d modulates oxidative responses induced potassium permanganate (KMnO₄) bovine endometrial epithelial cells (BEECs). Using KMnO₄ induce stress, we observed increases reactive oxygen species (ROS) malondialdehyde (MDA) levels, accompanied decreased...
A mild and versatile potassium trimethylsilanolate/butyronitrile (KOTMS/PrCN) reaction system for the deprotection further functionalization of N‐heterocycles in a single step has been developed. range N‐heterocycles, attached by various protecting groups, can be well transformed with good yields functionality tolerance. The protocol features high efficiency, simple operation, synthetic application.
Oxidative stress is a significant factor affecting reproductive efficiency in dairy cows, contributing to conditions such as endometritis that impair fertility and milk production. This study investigates the molecular mechanisms by which bta-let-7d modulates oxidative responses induced potassium permanganate (KMnO4) bovine endometrial epithelial cells (BEECs). Using KMnO4 induce stress, we observed increases reactive oxygen species (ROS) malondialdehyde (MDA) levels, accompanied decreased...
Streptococcal histidine triad protein was identified recently as a cell surface-associated family. Five members of this family (PhtA, PhtB, PhtD, PhtE and HtpA), derived from Streptococcus pneumoniae pyogenes, have been shown antigens that confer protection to the host on infection. In report, gene sequence highly homologous htpA phtD (designated htpS, suis) S. suis 2 Chinese strain 05ZYH33. Our data revealed htpS is extremely conserved in widely distributed 83% (29/35) 35 serotypes. It also...
Background This study aimed to quantify and compare serum aldosterone (sALD) levels through three different chemiluminescence immunoassays (CLIAs) liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis. Methods Serum samples from 221 patients with suspected primary aldosteronism (PA) were retrospectively included in this conducted at the Peking Union Medical College Hospital June August 2017. sALD determined using LC-MS/MS method CLIA systems, viz., DiaSorin® XL, iSYS Auto Lumo...
Japanese encephalitis (JE) is a vector-borne vaccine preventable infectious disease for which provides direct protection. China introduced nationwide JE vaccination of young children in 2007, rapidly achieving high coverage. In 2018, 1,800 cases were reported China, with morbidity and mortality rates 0.13/100,000 0.0097/100,000. Nationally, 64% among adults aged 40 years or older, northern 82% adults, mainly outbreaks. Severity varied little by age grouping. Compared the previous 10 years,...
Incidence of osteoarthritis and genu valgus is higher after partial meniscectomy the discoid lateral meniscus. We aimed to provide a biomechanical reference for slowing development complete meniscus (CDLM) surgery.Computed tomography magnetic resonance images knee were used establish finite element model knee. The was cut at 2-mm intervals obtain 10 models different widths (2-20 mm). instantaneous stress peak angle obtained by analysis under same coaxial load.When residual width greater than...